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Volumn 19, Issue 7, 2011, Pages 475-486

Fluorescence nanoparticles "quantum dots" as drug delivery system and their toxicity: A review

Author keywords

Cancer; Drug delivery; Imaging; Quantum dots; Toxicity

Indexed keywords

CADMIUM; CADMIUM SELENIDE; CADMIUM TELLURIDE; INDIUM ARSENIDE; NANOCRYSTAL; NANOPARTICLE; QUANTUM DOT; THIOGLYCOLIC ACID; TRIOCTYLPHOSPHINE OXIDE; UNCLASSIFIED DRUG; ZINC SULFIDE;

EID: 79960527809     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2010.526227     Document Type: Review
Times cited : (149)

References (53)
  • 1
    • 0346725932 scopus 로고    scopus 로고
    • The use of nanocrystals in biological detection
    • DOI 10.1038/nbt927
    • Alivisatos P. (2004). The use of nanocrystals in biological detection. Nat Biotechnol, 22, 47-52. (Pubitemid 38057955)
    • (2004) Nature Biotechnology , vol.22 , Issue.1 , pp. 47-52
    • Alivisatos, P.1
  • 2
    • 24744446848 scopus 로고    scopus 로고
    • Role of free cadmium and selenium ions in the potential mechanism for the enhancement of photoluminescence of CdSe quantum dots under ultraviolet irradiation
    • DOI 10.1166/jnn.2005.117
    • Bakalova R, Zhelev Z, Jose R, Nagase T, Ohba H, Ishikawa M, Baba Y. (2005). Role of free cadmium and selenium ions in the potential mechanism for the enhancement of photoluminescence of CdSe quantum dots under ultraviolet irradiation. J Nanosci Nanotechnol, 5, 887-894. (Pubitemid 41647849)
    • (2005) Journal of Nanoscience and Nanotechnology , vol.5 , Issue.6 , pp. 887-894
    • Bakalova, R.1    Zhelev, Z.2    Jose, R.3    Nagase, T.4    Ohba, H.5    Ishikawa, M.6    Baba, Y.7
  • 3
    • 58149493266 scopus 로고    scopus 로고
    • Electrohydrodynamic jetting behaviour of polyhedral oligomeric silsesquioxane nanocomposite
    • Bakhshi R, Edirisinghe MJ, Darbyshire A, Ahmad Z, Seifalian AM. (2009). Electrohydrodynamic jetting behaviour of polyhedral oligomeric silsesquioxane nanocomposite. J Biomater Appl, 23, 293-309.
    • (2009) J Biomater Appl , vol.23 , pp. 293-309
    • Bakhshi, R.1    Edirisinghe, M.J.2    Darbyshire, A.3    Ahmad, Z.4    Seifalian, A.M.5
  • 5
    • 77957766556 scopus 로고    scopus 로고
    • Nanosilver as a new generation of nanoproduct in biomedical applications
    • In Press
    • Chaloupka K, Malam Y, Seifalian AM. (2010). Nanosilver as a new generation of nanoproduct in biomedical applications. Trends Biotechnol (In Press
    • (2010) Trends Biotechnol
    • Chaloupka, K.1    Malam, Y.2    Seifalian, A.M.3
  • 6
    • 33751184633 scopus 로고    scopus 로고
    • CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals
    • Chan WH, Shiao NH, Lu PZ. (2006). CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals. Toxicol Lett, 167, 191-200.
    • (2006) Toxicol Lett , vol.167 , pp. 191-200
    • Chan, W.H.1    Shiao, N.H.2    Lu, P.Z.3
  • 7
    • 7544246309 scopus 로고    scopus 로고
    • Fluorescent CdSe/ZnS nanocrystal-peptide conjugates for long-term, nontoxic imaging and unclear targeting in living cells
    • Chen FQ, Gerion, D. (2004). Fluorescent CdSe/ZnS nanocrystal-peptide conjugates for long-term, nontoxic imaging and unclear targeting in living cells. Nano Lett, 4, 1827-1832.
    • (2004) Nano Lett , vol.4 , pp. 1827-1832
    • Chen, F.Q.1    Gerion, D.2
  • 9
    • 33847607194 scopus 로고    scopus 로고
    • Long-term exposure to CdTe quantum dots causes functional impairments in live cells
    • DOI 10.1021/la060093j
    • Cho SJ, Maysinger D, Jain M, Röder B, Hackbarth S, Winnik FM. (2007). Long-term exposure to CdTe quantum dots causes functional impairments in live cells. Langmuir, 23, 1974-1980. (Pubitemid 46406150)
    • (2007) Langmuir , vol.23 , Issue.4 , pp. 1974-1980
    • Cho, S.J.1    Maysinger, D.2    Jain, M.3    Roder, B.4    Hackbarth, S.5    Winnik, F.M.6
  • 12
  • 13
    • 0842287342 scopus 로고    scopus 로고
    • Probing the cytotoxicity of semiconductor quantum dots
    • Derfus AM, Chan WCW, Bhatia SN. (2003). Probing the cytotoxicity of semiconductor quantum dots. Nano Letters, 4, 11-18.
    • (2003) Nano Letters , vol.4 , pp. 11-18
    • Derfus, A.M.1    Wcw, C.2    Bhatia, S.N.3
  • 14
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • DOI 10.1038/nbt994
    • Gao X, Cui Y, Levenson RM, Chung LW, Nie S. (2004). In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol, 22, 969-976. (Pubitemid 39014473)
    • (2004) Nature Biotechnology , vol.22 , Issue.8 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.K.4    Nie, S.5
  • 16
    • 12744273180 scopus 로고    scopus 로고
    • Semiconductor quantum dots and free radical induced DNA nicking
    • Green M, Howman E. (2005). Semiconductor quantum dots and free radical induced DNA nicking. Chem Commun (Camb), 1, 121-123.
    • (2005) Chem Commun (Camb) , vol.1 , pp. 121-123
    • Green, M.1    Howman, E.2
  • 17
    • 33745913004 scopus 로고    scopus 로고
    • Pharmacokinetics of nanoscale quantum dots: In vivo distribution, sequestration, and clearance in the rat
    • DOI 10.1002/adfm.200500529
    • Fischer HC, Liu LC, Pang KS, Chan WC. (2006). Pharmacokinetics of nanoscale quantum dots: In vivo distribution, sequestration, and clearance in the rat. Adv Funct Mater, 16, 1299-1305. (Pubitemid 44049451)
    • (2006) Advanced Functional Materials , vol.16 , Issue.10 , pp. 1299-1305
    • Fischer, H.C.1    Liu, L.2    Pang, K.S.3    Chan, W.C.W.4
  • 18
    • 32044451341 scopus 로고    scopus 로고
    • A toxicologic review of quantum dots: Toxicity depends on physicochemical and environmental factors
    • DOI 10.1289/ehp.8284
    • Hardman R. (2006). A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect, 114, 165-172. (Pubitemid 43193634)
    • (2006) Environmental Health Perspectives , vol.114 , Issue.2 , pp. 165-172
    • Hardman, R.1
  • 19
    • 0346725825 scopus 로고    scopus 로고
    • Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body
    • DOI 10.1016/j.bbrc.2003.11.185
    • Hoshino A, Hanaki K, Suzuki K, Yamamoto K. (2004a). Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body. Biochem Biophys Res Commun, 314, 46-53. (Pubitemid 38058367)
    • (2004) Biochemical and Biophysical Research Communications , vol.314 , Issue.1 , pp. 46-53
    • Hoshino, A.1    Hanaki, K.-I.2    Suzuki, K.3    Yamamoto, K.4
  • 22
    • 27744548967 scopus 로고    scopus 로고
    • On the generation of free radical species from quantum dots
    • DOI 10.1002/smll.200500105
    • Ipe BI, Lehnig M, Niemeyer CM. (2005). On the generation of free radical species from quantum dots. Small, 1, 706-709. (Pubitemid 43951727)
    • (2005) Small , vol.1 , Issue.7 , pp. 706-709
    • Ipe, B.I.1    Lehnig, M.2    Niemeyer, C.M.3
  • 23
    • 0348087040 scopus 로고    scopus 로고
    • Long-term multiple color imaging of live cells using quantum dot bioconjugates
    • DOI 10.1038/nbt767
    • Jaiswal JK, Mattoussi H, Mauro JM, Simon SM. (2003). Longterm multiple color imaging of live cells using quantum dot bioconjugates. Nat Biotechnol, 21, 47-51. (Pubitemid 36055826)
    • (2003) Nature Biotechnology , vol.21 , Issue.1 , pp. 47-51
    • Jaiswal, J.K.1    Mattoussi, H.2    Mauro, J.M.3    Simon, S.M.4
  • 24
    • 34547887691 scopus 로고    scopus 로고
    • Biological applications of quantum dots
    • DOI 10.1016/j.biomaterials.2007.07.014, PII S014296120700539X
    • Jamieson T, Bakhshi R, Petrova D, Pocock R, Imani M, Seifalian AM. (2007). Biological applications of quantum dots. Biomaterials, 28, 4717-4732. (Pubitemid 47259173)
    • (2007) Biomaterials , vol.28 , Issue.31 , pp. 4717-4732
    • Jamieson, T.1    Bakhshi, R.2    Petrova, D.3    Pocock, R.4    Imani, M.5    Seifalian, A.M.6
  • 28
    • 0038780625 scopus 로고    scopus 로고
    • Water-soluble quantum dots for multiphoton fluorescence imaging in vivo
    • DOI 10.1126/science.1083780
    • Larson DR, Zipfel WR, Williams RM, Clark SW, Bruchez MP, Wise FW, Webb WW. (2003). Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science, 300, 1434-1436. (Pubitemid 36638163)
    • (2003) Science , vol.300 , Issue.5624 , pp. 1434-1436
    • Larson, D.R.1    Zipfel, W.R.2    Williams, R.M.3    Clark, S.W.4    Bruchez, M.P.5    Wise, F.W.6    Webb, W.W.7
  • 31
    • 55949126429 scopus 로고    scopus 로고
    • Clearance properties of nano-sized particles and molecules as imaging agents: Considerations and caveats
    • Longmire M, Choyke PL, Kobayashi H. (2008). Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine (Lond), 3, 703-717.
    • (2008) Nanomedicine (Lond) , vol.3 , pp. 703-717
    • Longmire, M.1    Choyke, P.L.2    Kobayashi, H.3
  • 32
    • 23044459574 scopus 로고    scopus 로고
    • Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots
    • DOI 10.1007/s00109-004-0629-x
    • Lovric J, Bazzi HS, Cuie Y, Fortin GR, Winnik FM, Maysinger D. (2005). Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots. J Mol Med, 83, 377-385. (Pubitemid 41201802)
    • (2005) Journal of Molecular Medicine , vol.83 , Issue.5 , pp. 377-385
    • Lovric, J.1    Bazzi, H.S.2    Cuie, Y.3    Fortin, G.R.A.4    Winnik, F.M.5    Maysinger, D.6
  • 33
    • 27744516368 scopus 로고    scopus 로고
    • Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death
    • DOI 10.1016/j.chembiol.2005.09.008, PII S107455210500298X
    • Lovric J, Cho SJ, Winnik FM, Maysinger D. (2005). Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death. Chem Biol, 12, 1227-1234. (Pubitemid 41628258)
    • (2005) Chemistry and Biology , vol.12 , Issue.11 , pp. 1227-1234
    • Lovric, J.1    Cho, S.J.2    Winnik, F.M.3    Maysinger, D.4
  • 34
    • 70350292588 scopus 로고    scopus 로고
    • Liposomes and nanoparticles: Nanosized vehicles for drug delivery in cancer
    • Malam Y, Loizidou M, Seifalian AM. (2009). Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer. Trends Pharmacol Sci, 30, 592-599.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 592-599
    • Malam, Y.1    Loizidou, M.2    Seifalian, A.M.3
  • 36
    • 74949083796 scopus 로고    scopus 로고
    • State of academic knowledge on toxicity and biological fate of quantum dots
    • Pelley JL, Daar AS, Saner MA. (2009). State of academic knowledge on toxicity and biological fate of quantum dots. Toxicol Sci, 112, 276-296.
    • (2009) Toxicol Sci , vol.112 , pp. 276-296
    • Pelley, J.L.1    Daar, A.S.2    Saner, M.A.3
  • 38
    • 33845750500 scopus 로고    scopus 로고
    • Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes
    • DOI 10.1038/sj.jid.5700508, PII 5700508
    • Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA. (2007). Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes. J Invest Dermatol, 127, 143-153. (Pubitemid 46005672)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.1 , pp. 143-153
    • Ryman-Rasmussen, J.P.1    Riviere, J.E.2    Monteiro-Riviere, N.A.3
  • 41
    • 46749091612 scopus 로고    scopus 로고
    • Bioconjugated quantum dots for in vivo molecular and cellular imaging
    • Smith AM, Duan H, Mohs AM, Nie S. (2008). Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv Drug Deliv Rev, 60, 1226-1240.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1226-1240
    • Smith, A.M.1    Duan, H.2    Mohs, A.M.3    Nie, S.4
  • 42
    • 54949159386 scopus 로고    scopus 로고
    • The cytotoxicity of cadmium based, aqueous phase-synthesized, quantum dots and its modulation by surface coating
    • Su Y, He Y, Lu H, Sai L, Li Q, Li W, Wang L, Shen P, Huang Q, Fan C. (2009). The cytotoxicity of cadmium based, aqueous phase-synthesized, quantum dots and its modulation by surface coating. Biomaterials, 30, 19-25.
    • (2009) Biomaterials , vol.30 , pp. 19-25
    • Su, Y.1    He, Y.2    Lu, H.3    Sai, L.4    Li, Q.5    Li, W.6    Wang, L.7    Shen, P.8    Huang, Q.9    Fan, C.10
  • 43
    • 46749130939 scopus 로고    scopus 로고
    • Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons
    • DOI 10.1289/ehp.11225
    • Tang M, Xing T, Zeng J, Wang H, Li C, Yin S, Yan D, Deng H, Liu J, Wang M, Chen J, Ruan DY. (2008). Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ Health Perspect, 116, 915-922. (Pubitemid 351943899)
    • (2008) Environmental Health Perspectives , vol.116 , Issue.7 , pp. 915-922
    • Tang, M.1    Xing, T.2    Zeng, J.3    Wang, H.4    Li, C.5    Yin, S.6    Yan, D.7    Deng, H.8    Liu, J.9    Wang, M.10    Chen, J.11    Ruan, D.-Y.12
  • 44
    • 20444400257 scopus 로고    scopus 로고
    • Redox redux: Revisiting PTPs and the control of cell signaling
    • DOI 10.1016/j.cell.2005.05.016, PII S0092867405004952
    • Tonks NK. (2005). Redox redux: revisiting PTPs and the control of cell signaling. Cell, 121, 667-670. (Pubitemid 40797589)
    • (2005) Cell , vol.121 , Issue.5 , pp. 667-670
    • Tonks, N.K.1
  • 45
    • 4644237609 scopus 로고    scopus 로고
    • Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy
    • DOI 10.1038/nm1096
    • Voura EB, Jaiswal JK, Mattoussi H, Simon SM. (2004). Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat Med, 10, 993-998. (Pubitemid 39273742)
    • (2004) Nature Medicine , vol.10 , Issue.9 , pp. 993-998
    • Voura, E.B.1    Jaiswal, J.K.2    Mattoussi, H.3    Simon, S.M.4
  • 48
    • 66149115270 scopus 로고    scopus 로고
    • Quantum dots and their potential biomedical applications in photosensitization for photodynamic therapy
    • Yaghini E, Seifalian AM, MacRobert AJ. (2009). Quantum dots and their potential biomedical applications in photosensitization for photodynamic therapy. Nanomedicine (Lond), 4, 353-363.
    • (2009) Nanomedicine (Lond) , vol.4 , pp. 353-363
    • Yaghini, E.1    Seifalian, A.M.2    MacRobert, A.J.3
  • 50
    • 42949166258 scopus 로고    scopus 로고
    • Quantum dots for cancer diagnosis and therapy: Biological and clinical perspectives
    • DOI 10.2217/17435889.3.1.83
    • Zhang H, Yee D, Wang C. (2008). Quantum dots for cancer diagnosis and therapy: biological and clinical perspectives. Nanomedicine (Lond), 3, 83-91. (Pubitemid 351611867)
    • (2008) Nanomedicine , vol.3 , Issue.1 , pp. 83-91
    • Zhang, H.1    Yee, D.2    Wang, C.3
  • 51
    • 41549109750 scopus 로고    scopus 로고
    • Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes
    • Zhang LW, Yu WW, Colvin VL, Monteiro-Riviere NA. (2008). Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes. Toxicol Appl Pharmacol, 228, 200-211.
    • (2008) Toxicol Appl Pharmacol , vol.228 , pp. 200-211
    • Zhang, L.W.1    Yu, W.W.2    Colvin, V.L.3    Monteiro-Riviere, N.A.4
  • 52
    • 33646398886 scopus 로고    scopus 로고
    • Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements
    • Zhang T, Stilwell JL, Gerion D, Ding L, Elboudwarej O, Cooke PA, Gray JW, Alivisatos AP, Chen FF. (2006). Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements. Nano Lett, 6, 800-808.
    • (2006) Nano Lett , vol.6 , pp. 800-808
    • Zhang, T.1    Stilwell, J.L.2    Gerion, D.3    Ding, L.4    Elboudwarej, O.5    Cooke, P.A.6    Gray, J.W.7    Alivisatos, A.P.8    Chen, F.F.9
  • 53


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