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(Cyclization of a p -chloro- N -(2-cyanophenyl)-phosphinimine hydrochloride salt to a 2-phosphaquinazoline system). At this point, we have no evidence to exclude the possibility of a 6π-electrocyclic ring closure. An earlier attempt to achieve this valuable transformation via intramolecular transfer of HCl from an aromatic amidinium hydrochloride salt to a neighboring nitrile group and subsequent cyclization to the 4-chloroquinazoline met with only limited success (25% yield after chromatogr. purification of the product mixture): Nagarathnam, D.; Asgari, D.; Shao, J.; Liu, X.-G.; Khire, U.; Wang, C.; Hart, B.; Boyer, S.; Weber, O.; Lynch, M.; Bankston, D. Int. Pat. Appl. WO 02076976A2, 2002.
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