Paw inflammation model in dogs for preclinical pharmacokinetic/ pharmacodynamic investigations of nonsteroidal anti-inflammatory drugs

Journal of Pharmacology and Experimental Therapeutics

Volumn 338, Issue 2, 2011, Pages 548-558

  Jeunesse, E C ^a,b   Bargues, I A ^a,b   Toutain, C E ^c   Lacroix, M Z ^a,b   Letellier, I M ^d   Giraudel, J M ^c   Toutain, Pierre Louis ^a,b  

^a TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c Novartis Centre de Recherche Santé Animale   (Switzerland)

^d Novartis Santé Animale   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; KAOLIN; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL LAMENESS; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DISEASE MODEL; DOG; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG RESPONSE; ENZYME INHIBITION; FEMALE; IC 50; IN VIVO STUDY; INFLAMMATION; MALE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; SCORING SYSTEM; SINGLE DRUG DOSE; THERMAL STIMULATION; VALIDATION STUDY; WALKING; WITHDRAWAL REFLEX;

EID: 79960497156     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.178350     Document Type: Article

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