Classical complement activation as a footprint for murine and human antiphospholipid antibody-induced fetal loss

Journal of Pathology

Volumn 225, Issue 4, 2011, Pages 502-511

  Cohen, Danielle ^a   Buurma, Aletta ^a   Goemaere, Natascha N ^b   Girardi, Guillermina ^c   Le Cessie, Saskia ^a   Scherjon, Sicco ^a   Bloemenkamp, Kitty W M ^a   De Heer, Emile ^a   Bruijn, Jan A ^a   Bajema, Ingeborg M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Stichting Pathan   (Netherlands)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

alternative pathway activation; antibody mediated rejection; antiphospholipid syndrome; classical complement activation; fetal loss; mannose binding lectin; placenta; recurrent miscarriage; systemic lupus erythaematosus

Indexed keywords

COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C4D; COMPLEMENT FACTOR D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; MANNOSE BINDING LECTIN; PHOSPHOLIPID ANTIBODY; PROPERDIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT DEPOSITION; COMPLEMENT LECTIN PATHWAY; CONTROLLED STUDY; FEMALE; FETOPLACENTAL UNIT; FETUS; FETUS DEATH; FETUS OUTCOME; FETUS WASTAGE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PLACENTA; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN BINDING; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; ANIMALS; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; BIOLOGICAL MARKERS; COMPLEMENT ACTIVATION; COMPLEMENT C1Q; COMPLEMENT C4; DISEASE MODELS, ANIMAL; FEMALE; FETAL DEATH; GESTATIONAL AGE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLACENTA; PREGNANCY; PREGNANCY OUTCOME;

EID: 79960450137     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2893     Document Type: Article

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