Primary CNS plasmablastic lymphoma: Report of a case with CSF cytology, flow cytometry, radiology, histological correlation, and review of the literature

Diagnostic Cytopathology

Volumn 39, Issue 8, 2011, Pages 616-620

  Urrego, Paula A Rodriguez ^a   Smethurst, Mark ^a   Fowkes, Mary ^a   Peterson, Bruce ^a   Strauchen, James ^a   Wu, Maoxin ^a   Szporn, Arnold H ^a   Chen, Hua ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

CNS; CSF cytology; plasmablastic lymphoma; primary

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BORTEZOMIB; CARBOPLATIN; CD19 ANTIGEN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; IMMUNOGLOBULIN KAPPA CHAIN; METHOTREXATE; PREDNISONE; STEROID; SYNDECAN 1; VINCRISTINE;

ADULT; BLURRED VISION; CASE REPORT; CD4 LYMPHOCYTE COUNT; CELL POPULATION; CEREBROSPINAL FLUID CYTOLOGY; CONCURRENT INFECTION; CONFUSION; CYTOLOGY; DIAGNOSTIC TEST ACCURACY STUDY; EPSTEIN BARR VIRUS INFECTION; FLOW CYTOMETRY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LETHALITY; MALE; MEDICAL LITERATURE; MENTAL HEALTH; MITOSIS; PLASMA CELL; POLYOMAVIRUS INFECTION; PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA; PRIMARY CENTRAL NERVOUS SYSTEM PLASMABLASTIC LYMPHOMA; PRIORITY JOURNAL; PROGNOSIS; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; RADIOLOGY; REVIEW; SLURRED SPEECH; TUMOR CELL;

BRAIN NEOPLASMS; CELL NUCLEUS SIZE; FLOW CYTOMETRY; HUMANS; LYMPHOMA, LARGE B-CELL, DIFFUSE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED;

EID: 79960428548     PISSN: 87551039     EISSN: 10970339     Source Type: Journal    
DOI: 10.1002/dc.21520     Document Type: Review

References (19)

1. Delecluse HJ, Anagnostopoulos I, Dallenbach F, et al. Plasmablastic lymphomas of the oral cavity: A new entity associated with the human immunodeficiency virus infection. Blood 1997; 89: 1413-1420. (Pubitemid 27080006)
2. Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World Health Organization (WHO) classification of tumors. Pathology and genetics of tumours of haematopoietic and lymphoid tissue. Lyon, France: IARC press; 2009. p 256-257.
3. Rafaniello Raviele P, Pruneri G, Maiorano E,. Plasmablastic lymphoma: A review. Oral Dis 2009; 15: 38-45.
4. Shuangshoti S, Assanasen T, Lerdlum S, Srikijvilaikul T, Intragumtornchai T, Thorner PS,. Primary central nervous system plasmablastic lymphoma in AIDS. Neuropathol Appl Neurobiol 2008; 34: 245-247. (Pubitemid 351327965)
5. Lin O, Gerhard R, Zerbini MC, Teruya-Feldstein J,. Cytologic features of plasmablastic lymphoma. Cancer 2005; 105: 139-144.
6. Reid-Nicholson M, Kavuri S, Ustun C, Crawford J, Nayak-Kapoor A, Ramalingam P,. Plasmablastic lymphoma: Cytologic findings in 5 cases with unusual presentation. Cancer 2008; 114: 333-341.
7. Colomo L, Loong F, Rives S, et al. Diffuse large B-cell lymphomas with plasmablastic differentiation represent a heterogeneous group of disease entities. Am J Surg Pathol 2004; 28: 736-747. (Pubitemid 38685887)
8. Dong HY, Scadden DT, de Leval L, Tang Z, Isaacson PG, Harris NL,. Plasmablastic lymphoma in HIV-positive patients: An aggressive Epstein-Barr virus-associated extramedullary plasmacytic neoplasm. Am J Surg Pathol 2005; 29: 1633-1641.
9. Ustun C, Reid-Nicholson M, Nayak-Kapoor A, et al. Plasmablastic lymphoma: CNS involvement, coexistence of other malignancies, possible viral etiology, and dismal outcome. Ann Hematol 2009; 88: 351-358.
10. Lin F, Zhang K, Quiery AT, Jr, Prichard J, Schuerch C,. Plasmablastic lymphoma of the cervical lymph nodes in a human immunodeficiency virus-negative patient: A case report and review of the literature. Arch Pathol Lab Med 2004; 128: 581-584. (Pubitemid 38579601)
11. Stewart JM, Krishnamurthy S,. Fine-needle aspiration cytology of a case of HIV-associated anaplastic myeloma. Diagn Cytopathol 2002; 27: 218-222.
12. Gupta RK, Naran S, Lallu S, Fauck R,. Cytodiagnosis of neoplasms of the central nervous system in cerebrospinal fluid samples with an application of selective immunostains in differentiation. Cytopathology 2004; 15: 38-43. (Pubitemid 38230799)
13. Bigner SH, Johnston WW,. The diagnostic challenge of tumors manifested initially by the shedding of cells into cerebrospinal fluid. Acta Cytol 1984; 28: 29-36. (Pubitemid 14178045)
14. Bigner SH, Jonston WW,. The cytopathology of cerebrospinal fluid. I. Nonneoplastic conditions, lymphoma and leukemia. Acta Cytol 1981; 25: 345-353.
15. Vega F, Chang CC, Medeiros LJ, et al. Plasmablastic lymphomas and plasmablastic plasma cell myelomas have nearly identical immunophenotypic profiles. Mod Pathol 2005; 18: 806-815. (Pubitemid 40780514)
16. Jaffe ES,. Anaplastic large cell lymphoma: The shifting sands of diagnostic hematopathology. Mod Pathol 2001; 14: 219-228. (Pubitemid 32246828)
17. Kambham N, Kong C, Longacre TA, Natkunam Y,. Utility of syndecan-1 (CD138) expression in the diagnosis of undifferentiated malignant neoplasms: A tissue microarray study of 1,754 cases. Appl Immunohistochem Mol Morphol 2005; 13: 304-310. (Pubitemid 41697391)
18. Lu L, Wilkinson EJ, Yachnis AT,. CSF cytology of atypical teratoid/rhabdoid tumor of the brain in a two-year-old girl: A case report. Diagn Cytopathol 2000; 23: 329-332.
19. Qian X, Goumnerova LC, De Girolami U, Cibas ES,. Cerebrospinal fluid cytology in patients with ependymoma: A bi-institutional retrospective study. Cancer 2008; 114: 307-314.