Ophthalmological complications in hepatitis C virus infection: Side effect of interferon therapy or a direct role of HCV?

Biomedicine and Pharmacotherapy

Volumn 65, Issue 4, 2011, Pages 317-318

  Pazienza, Valerio ^a  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

Author keywords

HCV; Ocular syndromes; Tumour

Indexed keywords

ANKYRIN; AUTOANTIGEN; CORE PROTEIN; DNA DIRECTED DNA POLYMERASE DELTA; INTERFERON; MITOCHONDRIAL DNA; NUCLEAR PROTEIN; RAB27A PROTEIN; RAL PROTEIN; RBAK PROTEIN; RETINOBLASTOMA 1 PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL THERAPY; AUTOIMMUNITY; CHOROIDEREMIA; EXTERNAL OPHTHALMOPLEGIA; EYE DISEASE; GENETIC REGULATION; HEPATITIS C; IN VITRO STUDY; INFECTION RISK; LACRIMAL FLUID; LETTER; LOSS OF FUNCTION MUTATION; MITOCHONDRIAL DNA REPLICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; UVEA; UVEITIS; VIRUS TRANSMISSION;

ANTIVIRAL AGENTS; EYE DISEASES; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERFERONS;

EID: 79960428174     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2011.04.004     Document Type: Letter

References (10)

1. Cuthbertson F.M., Davies M., McKibbin M. Is screening for interferon retinopathy in hepatitis C justified?. Ophthalmol 2004, 88(12):1518-1520.
2. Rossi C., Scotton P.G., Farina F., Vaglia A. Retinopathy in chronic hepatitis C patients during interferon treatment: a case report. Infez Med 2010, 18(4):267-269.
3. Sene D., Touitou V., Bodaghi B., Saadoun D., Perlemuter G., Cassoux N., et al. Intraocular complications of IFN-alpha and ribavirin therapy in patients with chronic viral hepatitis C. World J Gastroenterol 2007, 13(22):3137-3140.
4. Pazienza V., Clement S., Pugnale P., Conzelmann S., Pascarella S., Mangia A., et al. Gene expression profile of Huh-7 cells expressing hepatitis C virus genotype 1b or 3a core proteins. Liver Int 2009, 29(5):661-669.
5. Dou J., Liu P., Wang J., Zhang X. Preliminary analysis of gene expression profiles in HepG2 cell line induced by different genotype core proteins of HCV. Cell Mol Immunol 2006, 3(3):227-233.
6. Domínguez-Villar M., Muñoz-Suano A., Anaya-Baz B., Aguilar S., Novalbos J.P., Giron J.A., et al. Hepatitis C virus core protein up-regulates anergy-related genes and a new set of genes, which affects T cell homeostasis. J Leukocyte Biol 2007, 82:1301-1310.
7. Mendel I., Muraine M., Riachi G., el Forzli F., Bertin C., Colin R., et al. Detection and genotyping of the hepatitis C RNA in tear fluid from patients with chronic hepatitis C. J Med Virol 1997, 51(3):231-233.
8. Yamada K., Senju S., Nakatsura T. Identification of a Novel Autoantigen UACA in Patients with Panuveitis. BBRC 2001. Biochem Biophys Res Commun 2001, 280(4):1169-1176.
9. Tolmachova T., Ramalho J.S., Anant J.S., Schultz R.A., Huxley C.M., Seabra M.C. Cloning, mapping and characterization of the human RAB27A gene. Gene 1999, 239(1):109-116.
10. Lohmann D. Retinoblastoma. Adv Exp Med Biol 2010, 685:220-227.