Measuring differences in compositional properties of bone tissue by confocal raman spectroscopy

Calcified Tissue International

Volumn 89, Issue 2, 2011, Pages 111-122

  Nyman, Jeffry S ^a,b,c,e   Makowski, Alexander J ^a,c   Patil, Chetan A ^c   Masui, T Philip ^c   O'Quinn, Elizabeth C ^b   Bi, Xiaohong ^c   Guelcher, Scott A ^c   Nicollela, Daniel P ^d   Mahadevan Jansen, Anita ^c  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d SOUTHWEST RESEARCH INSTITUTE   (United States)

^e Medical Center East   (United States)

Author keywords

Collagen; Cortical bone; Embedding; Mineral; Raman

Indexed keywords

ADULT; AGED; ANALYTIC METHOD; ARTICLE; BIOCHEMICAL COMPOSITION; BONE EXAMINATION; BONE MINERAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; RAMAN SPECTROMETRY;

AGED, 80 AND OVER; ANIMALS; BONE AND BONES; BONE DENSITY; FEMALE; HUMANS; INDIVIDUALITY; MALE; MICE; MICRODISSECTION; MIDDLE AGED; ORGAN SPECIFICITY; RATS; SPECTRUM ANALYSIS, RAMAN; TISSUE EMBEDDING; TISSUE PRESERVATION; WEIGHTS AND MEASURES;

EID: 79960425063     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-011-9497-x     Document Type: Article

References (45)

1. JA Kanis O Johnell A Oden A Dawson C De Laet B Jonsson 2001 Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds Osteoporos Int 12 989 995 11846333 10.1007/s001980170006 1:STN:280:DC%2BD387hsValtQ%3D%3D (Pubitemid 34105967)
2. CM Schnitzler 1993 Bone quality: a determinant for certain risk factors for bone fragility Calcif Tissue Int 53 suppl 1 S27 S31 8275376 10.1007/BF01673398
3. CH Turner 2002 Biomechanics of bone: determinants of skeletal fragility and bone quality Osteoporos Int 13 97 104 11905527 10.1007/s001980200000 1:STN:280:DC%2BD387ntlaguw%3D%3D (Pubitemid 34241029)
4. JY Rho L Kuhn-Spearing P Zioupos 1998 Mechanical properties and the hierarchical structure of bone Med Eng Phys 20 92 102 9679227 10.1016/S1350-4533(98)00007-1 1:STN:280:DyaK1czksVWksg%3D%3D (Pubitemid 28318322)
5. W Opsahl H Zeronian M Ellison D Lewis RB Rucker RS Riggins 1982 Role of copper in collagen cross-linking and its influence on selected mechanical properties of chick bone and tendon J Nutr 112 708 716 6121843 1:CAS:528:DyaL38XitFKnsLw%3D (Pubitemid 12091450)
6. J Jonas J Burns EW Abel MJ Cresswell JJ Strain CR Paterson 1993 Impaired mechanical strength of bone in experimental copper deficiency Ann Nutr Metab 37 245 252 8311418 10.1159/000177774 1:CAS:528:DyaK2cXltlGisg%3D%3D (Pubitemid 23341394)
7. H Oxlund M Barckman G Ortoft TT Andreassen 1995 Reduced concentrations of collagen cross-links are associated with reduced strength of bone Bone 17 365S 371S 8579939 1:CAS:528:DyaK2MXptlKjtrY%3D
8. O Akkus A Polyakova-Akkus F Adar MB Schaffler 2003 Aging of microstructural compartments in human compact bone J Bone Miner Res 18 1012 1019 12817753 10.1359/jbmr.2003.18.6.1012 1:CAS:528:DC%2BD3sXkslOhsb4%3D (Pubitemid 37294937)
9. NE Lane W Yao M Balooch RK Nalla G Balooch S Habelitz JH Kinney LF Bonewald 2006 Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice J Bone Miner Res 21 466 476 16491295 10.1359/JBMR.051103 1:CAS:528:DC%2BD28XisFGqurY%3D
10. A Carden MD Morris 2000 Application of vibrational spectroscopy to the study of mineralized tissues (review) J Biomed Opt 5 259 268 10958610 10.1117/1.429994 1:CAS:528:DC%2BD3cXmtFOhu7Y%3D
11. X Bi CA Patil CC Lynch GM Pharr A Mahadevan-Jansen JS Nyman 2011 Raman and mechanical properties correlate at whole bone- and tissue-levels in a genetic mouse model J Biomech 44 297 303 21035119 10.1016/j.jbiomech.2010.10.009
12. JA Timlin A Carden MD Morris RM Rajachar DH Kohn 2000 Raman spectroscopic imaging markers for fatigue-related microdamage in bovine bone Anal Chem 72 2229 2236 10845368 10.1021/ac9913560 1:CAS:528:DC%2BD3cXitlehu7w%3D (Pubitemid 30322285)
13. MV Schulmerich KA Dooley MD Morris TM Vanasse SA Goldstein 2006 Transcutaneous fiber optic Raman spectroscopy of bone using annular illumination and a circular array of collection fibers J Biomed Opt 11 060502 17212521 10.1117/1.2400233 (Pubitemid 46323001)
14. YN Yeni J Yerramshetty O Akkus C Pechey CM Les 2006 Effect of fixation and embedding on Raman spectroscopic analysis of bone tissue Calcif Tissue Int 78 363 371 16830201 10.1007/s00223-005-0301-7 1:CAS:528:DC%2BD28XntVSmsr0%3D (Pubitemid 44078535)
15. M Kazanci P Roschger EP Paschalis K Klaushofer P Fratzl 2006 Bone osteonal tissues by Raman spectral mapping: orientation-composition J Struct Biol 156 489 496 16931054 10.1016/j.jsb.2006.06.011 1:CAS:528:DC%2BD28Xht1CgsbzF (Pubitemid 44781298)
16. M Kazanci HD Wagner NI Manjubala HS Gupta E Paschalis P Roschger P Fratzl 2007 Raman imaging of two orthogonal planes within cortical bone Bone 41 456 461 17602910 10.1016/j.bone.2007.04.200 1:STN:280:DC%2BD2srjsleisQ%3D%3D (Pubitemid 47208629)
17. TG Bromage HM Goldman SC McFarlin J Warshaw A Boyde CM Riggs 2003 Circularly polarized light standards for investigations of collagen fiber orientation in bone Anat Rec B New Anat 274 157 168 12964206 10.1002/ar.b.10031 (Pubitemid 37248089)
18. Morris MD (2010) Raman spectroscopy of bone and cartilage. In: Matousek P, Morris MD (eds) Emerging Raman applications and techniques in biomedical and pharmaceutical fields. Springer, New York, pp 347-364
19. G Boivin Y Bala A Doublier D Farlay LG Ste-Marie PJ Meunier PD Delmas 2008 The role of mineralization and organic matrix in the microhardness of bone tissue from controls and osteoporotic patients Bone 43 532 538 18599391 10.1016/j.bone.2008.05.024 1:STN:280:DC%2BD1critFyrsg%3D%3D
20. C Bergot Y Wu E Jolivet LQ Zhou JD Laredo V Bousson 2009 The degree and distribution of cortical bone mineralization in the human femoral shaft change with age and sex in a microradiographic study Bone 45 435 442 19501681 10.1016/j.bone.2009.05.025 1:STN:280:DC%2BD1Mrkt12nug%3D%3D
21. JY Rho ME Roy II TY Tsui GM Pharr 1999 Elastic properties of microstructural components of human bone tissue as measured by nanoindentation J Biomed Mater Res 45 48 54 10397957 10.1002/(SICI)1097-4636(199904)45:1<48:: AID-JBM7>3.0.CO;2-5 1:CAS:528:DyaK1MXhtVWrs7c%3D (Pubitemid 29068438)
22. CA Lieber A Mahadevan-Jansen 2003 Automated method for subtraction of fluorescence from biological Raman spectra Appl Spectrosc 57 1363 1367 14658149 10.1366/000370203322554518 1:CAS:528:DC%2BD3sXovVyisbk%3D
23. T Hofmann F Heyroth H Meinhard W Franzel K Raum 2006 Assessment of composition and anisotropic elastic properties of secondary osteon lamellae J Biomech 39 2282 2294 16144702 10.1016/j.jbiomech.2005.07.009 (Pubitemid 44223535)
24. S Nie KL Bergbauer JT Ho JF Kuck Jr NT Yu 1990 Applications of near-infrared Fourier transform Raman spectroscopy in biology and medicine Spectroscopy 5 24 32
25. MM Giraud-Guille 1988 Twisted plywood architecture of collagen fibrils in human compact bone osteons Calcif Tissue Int 42 167 180 3130165 10.1007/BF02556330 1:CAS:528:DyaL1cXhs1Gisbk%3D (Pubitemid 18068482)
26. J Bandekar 1992 Amide modes and protein conformation Biochim Biophys Acta 1120 123 143 1373323 10.1016/0167-4838(92)90261-B 1:CAS:528:DyaK38XitlSqtLw%3D
27. S Gourion-Arsiquaud J Burket L Havill E Dicarlo S Doty R Mendelsohn M van der Meulen A Boskey 2009 Spatial variation in osteonal bone properties relative to tissue and animal age J Bone Miner Res 24 1271 1281 19210217 10.1359/jbmr.090201
28. O Akkus F Adar MB Schaffler 2004 Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone Bone 34 443 453 15003792 10.1016/j.bone.2003.11.003 1:CAS:528:DC%2BD2cXhvFalu7Y%3D (Pubitemid 38314909)
29. E Donnelly AL Boskey SP Baker MC van der Meulen 2010 Effects of tissue age on bone tissue material composition and nanomechanical properties in the rat cortex J Biomed Mater Res A 92 1048 1056 19301272
30. JS Yerramshetty C Lind O Akkus 2006 The compositional and physicochemical homogeneity of male femoral cortex increases after the sixth decade Bone 39 1236 1243 16860007 10.1016/j.bone.2006.06.002 1:CAS:528:DC%2BD28Xht1Krsb3O (Pubitemid 44834503)
31. JS Yerramshetty O Akkus 2008 The associations between mineral crystallinity and the mechanical properties of human cortical bone Bone 42 476 482 18187375 10.1016/j.bone.2007.12.001 1:CAS:528:DC%2BD1cXitVOmtbY%3D
32. O de Carmejane MD Morris MK Davis L Stixrude M Tecklenburg RM Rajachar DH Kohan 2005 Bone chemical structure response to mechanical stress studied by high pressure Raman spectroscopy Calcif Tissue Int 76 207 213 15742234 10.1007/s00223-004-0168-z (Pubitemid 41557149)
33. JG Ramasamy O Akkus 2007 Local variations in the micromechanical properties of mouse femur: the involvement of collagen fiber orientation and mineralization J Biomech 40 910 918 16678186 10.1016/j.jbiomech.2006.03.002 1:STN:280:DC%2BD2s7htlWmsw%3D%3D (Pubitemid 46273453)
34. MJ Silva MD Brodt B Wopenka S Thomopoulos D Williams MH Wassen M Ko N Kusano RA Bank 2006 Decreased collagen organization and content are associated with reduced strength of demineralized and intact bone in the SAMP6 mouse J Bone Miner Res 21 78 88 16355276 10.1359/JBMR.050909 (Pubitemid 43023229)
35. JJ Freeman B Wopenka MJ Silva JD Pasteris 2001 Raman spectroscopic detection of changes in bioapatite in mouse femora as a function of age and in vitro fluoride treatment Calcif Tissue Int 68 156 162 11351499 10.1007/s002230001206 1:CAS:528:DC%2BD3MXjvFagsbc%3D (Pubitemid 32374476)
36. NB Kavukcuoglu E Arteaga-Solis S Lee-Arteaga F Ramirez AB Mann 2007 Nanomechanics and Raman spectroscopy of fibrillin 2 knock-out mouse bones J Mater Sci 42 8788 8794 10.1007/s10853-007-1918-x 1:CAS:528:DC%2BD2sXpvVWqurs%3D (Pubitemid 47353301)
37. NB Kavukcuoglu DT Denhardt N Guzelsu AB Mann 2007 Osteopontin deficiency and aging on nanomechanics of mouse bone J Biomed Mater Res A 83 136 144 17390367 (Pubitemid 47435658)
38. NB Kavukcuoglu P Patterson-Buckendahl AB Mann 2009 Effect of osteocalcin deficiency on the nanomechanics and chemistry of mouse bones J Mech Behav Biomed 2 254 348 10.1016/j.jmbbm.2008.10.010
39. JM Wallace K Golcuk MD Morris DH Kohn 2009 Inbred strain-specific response to biglycan deficiency in the cortical bone of C57BL6/129 and C3H/He mice J Bone Miner Res 24 1002 1012 19113913 10.1359/jbmr.081259
40. DH Kohn ND Sahar JM Wallace K Golcuk MD Morris 2009 Exercise alters mineral and matrix composition in the absence of adding new bone Cells Tissues Organs 189 33 37 18703871 10.1159/000151452
41. G Balooch M Balooch RK Nalla S Schilling EH Filvaroff GW Marshall SJ Marshall RO Ritchie R Derynck T Alliston 2005 TGF-beta regulates the mechanical properties and composition of bone matrix Proc Natl Acad Sci USA 102 18813 18818 16354837 10.1073/pnas.0507417102 1:CAS:528:DC%2BD28XivVyrsA%3D%3D (Pubitemid 43049527)
42. JW Ager RK Nalla KL Breeden RO Ritchie 2005 Deep-ultraviolet Raman spectroscopy study of the effect of aging on human cortical bone J Biomed Opt 10 034012 16229656 10.1117/1.1924668 1:STN:280:DC%2BD2MrlsVamtQ%3D%3D (Pubitemid 41236406)
43. J Shen L Fan J Yang AG Shen JM Hu 2010 A longitudinal Raman microspectroscopic study of osteoporosis induced by spinal cord injury Osteoporos Int 21 81 87 19436936 10.1007/s00198-009-0949-3 1:STN:280: DC%2BD1MjptlWhtg%3D%3D
44. BR McCreadie MD Morris TC Chen D Sudhaker Rao WF Finney E Widjaja SA Goldstein 2006 Bone tissue compositional differences in women with and without osteoporotic fracture Bone 39 1190 1195 16901772 10.1016/j.bone.2006.06.008 1:CAS:528:DC%2BD28Xht1Krsb3M (Pubitemid 44827927)
45. CP Tarnowski MA Ignelzi Jr MD Morris 2002 Mineralization of developing mouse calvaria as revealed by Raman microspectroscopy J Bone Miner Res 17 1118 1126 12054168 10.1359/jbmr.2002.17.6.1118 (Pubitemid 34535151)