The reason for failure of on-demand PPI therapy in NERD patients

Neurogastroenterology and Motility

Volumn 23, Issue 8, 2011, Pages 811-

  Savarino, E ^a   Zentilin, P ^a   Savarino, V ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTON PUMP INHIBITOR;

DRUG EFFICACY; DRUG TREATMENT FAILURE; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL ENDOSCOPY; HEARTBURN; HUMAN; LETTER; NON EROSIVE REFLUX DISEASE; PRIORITY JOURNAL;

FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; OMEPRAZOLE; PROTON PUMP INHIBITORS;

EID: 79960424322     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2011.01722.x     Document Type: Letter

References (5)

1. Wu JCY, Lai LH, Chow DKL et al. Concomitant irritable bowel syndrome is associated with failure of step-down on-demand proton pump inhibitor treatment in patients with gastro-esophageal reflux disease. Neurogastroenterol Motil 2011; 23: 155-e31.
2. Savarino E, Pohl D, Zentilin P et al. Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease. Gut 2009; 58: 1185-91.
3. Tack J, Talley NJ, Camilleri M et al. Functional gastroduodenal disorders. Gastroenterology 2006; 130: 1466-79.
4. Savarino E, Zentilin P, Tutuian R et al. The role of non-acid reflux in NERD: lessons learned from impedance-pH monitoring in 150 patients off therapy. Am J Gastroenterol 2008; 103: 2685-93.
5. Mainie I, Tutuian R, Shay S et al. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicenter study using combined ambulatory impedance-pH monitoring. Gut 2006; 55: 1398-402.