Electrical responses to chemosensory stimulation recorded from the vomeronasal duct and the respiratory epithelium in humans

International Journal of Psychophysiology

Volumn 81, Issue 2, 2011, Pages 116-120

  Hummel, T ^a   Schultz, S ^a   Witt, M ^b   Hatt, H ^c  

^a UNIVERSITY OF DRESDEN MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Electro olfactogram; Electrophysiology; Irritation; Mucosal potential; Olfaction; Trigeminal

Indexed keywords

ANDROSTA 4,16 DIEN 3 ON; CARBON DIOXIDE; CENTRAL STIMULANT AGENT; ESTRATETRAENOL; UNCLASSIFIED DRUG;

ADULT; ANOSMIA; ARTICLE; ELECTRODE; ELECTROSTIMULATION; ENDOSCOPY; FEMALE; GAS; HUMAN; HUMAN EXPERIMENT; MALE; NOSE MUCOSA; OLFACTOMETER; RESPIRATORY EPITHELIUM; SENSATION; SENSORY STIMULATION; SEX DIFFERENCE; THERMAL ANALYSIS; TRIGEMINAL NERVE; VOMERONASAL ORGAN;

ADULT; ELECTROENCEPHALOGRAPHY; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; HUMANS; MALE; MIDDLE AGED; NASAL MUCOSA; ODORS; RESPIRATORY MUCOSA; SMELL; STIMULATION, CHEMICAL; TRIGEMINAL NERVE; YOUNG ADULT;

EID: 79960404090     PISSN: 01678760     EISSN: 18727697     Source Type: Journal    
DOI: 10.1016/j.ijpsycho.2011.05.002     Document Type: Article

References (39)

1. Berliner D.L., Monti-Bloch L., Jennings-White C., Diaz-Sanchez V. The functionality of the human vomeronasal organ (VNO): evidence for steroid receptors. J. Steroid Biochem. Mol. Biol. 1996, 58:259-265.
2. Boyle J.A., Lundström J.N., Knecht M., Jones-Gotman M., Schaal B., Hummel T. On the trigeminal percept of androstenone and its implications on the rate of specific anosmia. J. Neurobiol. 2006, 66:1501-1510.
3. Brown J.W. The nervus terminalis in insectivorous bat embryos and notes on its presence during human ontogeny. Ann. N. Y. Acad. Sci. 1987, 287:184-200.
4. Cometto-Muniz E., Cain W.S. Temporal integration of pungency. Chem. Senses 1984, 8:315-327.
5. Cometto-Muniz J.E., Cain W.S., Abraham M.H., Kumarsingh R. Sensory properties of selected terpenes. Thresholds for odor, nasal pungency, nasal localization, and eye irritation. Ann. N. Y. Acad. Sci. 1998, 855:648-651.
6. Doty R.L., Brugger W.P.E., Jurs P.C., Orndorff M.A., Snyder P.J., Lowry L.D. Intranasal trigeminal stimulation from odorous volatiles: psychometric responses from anosmic and normal humans. Physiol. Behav. 1978, 20:175-185.
7. Eloit C., Wassef M., Ferrand J., Bensimon J.L., Trotier D. Observations on adult human vomeronasal organs. Chem. Senses 1998, 24:64.
8. Fröhlich R. Ueber einige Modificationen des Geruchsinnes. Akad. Wiss. Wien Math.-Nat. CL 1851, 6:322-328.
9. Garcia Medina M.R., Cain W.S. Bilateral integration in the common chemical sense. Physiol. Behav. 1982, 29:349-353.
10. Getchell T.V. Analysis of intracellular recordings from salamander olfactory epithelium. Brain Res. 1977, 123:75-286.
11. Hummel T., Livermore A., Hummel C., Kobal G. Chemosensory event-related potentials: relation to olfactory and painful sensations elicited by nicotine. Electroencephalogr. Clin. Neurophysiol. 1992, 84:192-195.
12. Hummel T., Kobal G., Gudziol H., Mackay-Sim A. Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3000 subjects. Eur. Arch. Otorhinolaryngol. 2007, 264:237-243.
13. Humphrey T. The development of the olfactory and the accessory olfactory formations in human embryos and fetuses. J. Comp. Neurol. 1940, 73:431-468.
14. Knecht M., Hummel T. Recording of the human electro-olfactogram. Physiol. Behav. 2004, 83:13-19.
15. Knecht M., Kühnau D., Hüttenbrink K.B., Witt M., Hummel T. Frequency and localization of the putative vomeronasal organ in humans in relation to age and gender. Laryngoscope 2001, 111:448-452.
16. Kobal G. Elektrophysiologische Untersuchungen des menschlichen Geruchssinns 1981, Thieme Verlag, Stuttgart.
17. Kobal G., Hummel C., Nürnberg B., Brune K. Effects of pentazocine and acetylsalicylic acid on pain-rating, pain-related evoked potentials and vigilance in relationship to pharmacokinetic parameters. Agents Actions 1990, 29(3/4):342-359.
18. Kobal G., Hummel T., Sekinger B., Barz S., Roscher S., Wolf S.R. "Sniffin' Sticks": screening of olfactory performance. Rhinology 1996, 34:222-226.
19. Laska M., Distel H., Hudson R. Trigeminal perception of odorant quality in congenitally anosmic subjects. Chem. Senses 1997, 22:447-456.
20. Mast T.G., Samuelsen C.L. Human pheromone detection by the vomeronasal organ: unnecessary for mate selection?. Chem. Senses 2009, 34:529-531.
21. Meisami E., Bhatnagar K.P. Structure and diversity in mammalian accessory olfactory bulb. Microsc. Res. Tech. 1998, 43:476-499.
22. Meisami E., Mikhail L., Baim D., Bhatnagar K.P. Human olfactory bulb: aging of glomeruli and mitral cells and a search. Ann. N. Y. Acad. Sci. 1998, 855:708-715.
23. Meredith M. Human vomeronasal organ function: a critical review of best and worst cases. Chem. Senses 2001, 26:433-445.
24. Monti-Bloch L., Grosser B.I. Effect of putative pheromones on the electrical activity of the human vomeronasal organ and olfactory epithelium. J. Steroid Biochem. Mol. Biol. 1991, 39:573-582.
25. Monti-Bloch L., Jennings-White C., Dolberg D.S., Berliner D.L. The human vomeronasal system. Psychoneuroendocrinology 1994, 19:673-686.
26. Monti-Bloch L., Jennings-White C., Berliner D.L. The human vomeronasal system. A review. Ann. N. Y. Acad. Sci. 1998, 855:373-389.
27. Ottoson D. Analysis of the electrical activity of the olfactory epithelium. Acta Physiol. Scand. 1956, 35:1-83.
28. Roithmann R., Cole P., Chapnik J., Barreto S.M., Szalai J.P., Zamel N. Acoustic rhinometry, rhinomanometry, and the sensation of nasal patency: a correlative study. J. Otolaryngol. 1994, 23:454-458.
29. Ruysch F. Thesaurus Anatomicus 1703, vol. 3. Wolters, Amsterdam.
30. Smith T.D., Siegel M.I., Burrows A.M., Mooney M.P., Burdi A.R., Fabrizio P.A., Clemente F.R. Searching for the vomeronasal organ of adult humans: preliminary findings on location, structure, and size. Microsc. Res. Tech. 1998, 41:483-491.
31. Smith T.D., Buttery T.A., Bhatnagar K.P., Burrows A.M., Mooney M.P., Siegel M.I. Anatomical position of the vomeronasal organ in postnatal humans. Ann. Anat. 2001, 183:475-479.
32. Stensaas L.J., Lavker R.M., Monti-Bloch L., Grosser B.I., Berliner D.L. Ultrastructure of the human vomeronasal organ. J. Steroid Biochem. Mol. Biol. 1991, 39:553-560.
33. Thürauf N., Friedel I., Hummel C., Kobal G. The mucosal potential elicited by noxious chemical stimuli: is it a peripheral nociceptive event. Neurosci. Lett. 1991, 128:297-300.
34. Trotier D., Doving K.B. Anatomical description of a new organ in the nose of domesticated animals' by Ludvig Jacobson (1813). Chem. Senses 1998, 23:743-754.
35. Wang Z., Nudelman A., Storm D.R. Are pheromones detected through the main olfactory epithelium?. Mol. Neurobiol. 2007, 35:317-323.
36. Witt M., Hummel T. Vomeronasal versus olfactory epithelium: is there a cellular basis for human vomeronasal perception?. Int. Rev. Cytol. 2006, 248C:209-259.
37. Witt M., Georgiewa B., Knecht M., Hummel T. On the chemosensory nature of the vomeronasal epithelium in adult humans. Histochem. Cell Biol. 2002, 117:493-509.
38. Wysocki C.J., Meredith M. The vomeronasal system. Neurobiology of Taste and Smell 1991, 125-150. Krieger Publishing Company, Malabar, Florida. T.E. Finger, W.L. Silver (Eds.).
39. Wysocki C.J., Preti G. Facts, fallacies, fears, and frustrations with human pheromones. Anat. Rec. A Discov. Mol. Cell Evol. Biol. 2004, 281:1201-1211.