Defining criteria to interpret multilocus variablenumber tandem repeat analysis to aid Clostridium difficile outbreak investigation

Journal of Medical Microbiology

Volumn 60, Issue 8, 2011, Pages 1095-1100

  Broukhanski, George ^a,b   Simor, Andrew ^a   Pillai, Dylan R ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b PUBLIC HEALTH ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; CLONAL VARIATION; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; CLUSTER ANALYSIS; COMPUTER PROGRAM; DEMOGRAPHY; EPIDEMIC; FECES ANALYSIS; FEMALE; GENE LOCUS; GENETIC ANALYSIS; HEALTH SCIENCE; HOSPITAL ADMISSION; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MULTILOCUS VARIABLE NUMBER TANDEM REPEAT ANALYSIS; PHYLOGENETIC TREE; PRIORITY JOURNAL; VARIABLE NUMBER OF TANDEM REPEAT;

AGED; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; DISEASE OUTBREAKS; DNA, BACTERIAL; FECES; FEMALE; HUMANS; MALE; MULTILOCUS SEQUENCE TYPING; NORTH AMERICA; PHYLOGENY; POPULATION SURVEILLANCE;

EID: 79960395637     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.029819-0     Document Type: Article

References (15)

1. Antikainen, J., Pasanen, T., Mero, S., Tarkka, E., Kirveskari, J., Kotila, S., Mentula, S., Könönen E., Virolainen-Julkunen, A. R. & other authors (2009). Detection of virulence genes of Clostridium difficile by multiplex PCR. APMIS 117, 607-613.
2. Aspinall, S. T. & Hutchinson, D. N. (1992). New selective medium for isolating Clostridium difficile from faeces. J Clin Pathol 45, 812-814.
3. Broukhanski, G., Low, D. E. & Pillai, D. R. (2011). Modified multiplelocus variable-number tandem-repeat analysis for rapid identification and typing of Clostridium difficile during institutional outbreaks. J Clin Microbiol 49, 1983-1986.
4. Fawley, W. N., Freeman, J., Smith, C., Harmanus, C., van den Berg, R. J., Kuijper, E. J. & Wilcox, M. H. (2008). Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains. J Clin Microbiol 46, 954- 960.
5. Goorhuis, A., Legaria, M. C., van den Berg, R. J., Harmanus, C., Klaassen, C. H., Brazier, J. S., Lumelsky, G. & Kuijper, E. J. (2009). Application of multiple-locus variable-number tandem-repeat analysis to determine clonal spread of toxin A-negative Clostridium difficile in a general hospital in Buenos Aires, Argentina. Clin Microbiol Infect 15, 1080-1086.
6. Ichikawa, K., Yagi, T., Inagaki, T., Moriyama, M., Nakagawa, T., Uchiya, K., Nikai, T. & Ogawa, K. (2010). Molecular typing of Mycobacterium intracellulare using multilocus variable-number of tandem-repeat analysis: identification of loci and analysis of clinical isolates. Microbiology 156, 496-504.
7. Killgore, G., Thompson, A., Johnson, S., Brazier, J., Kuijper, E., Pepin, J., Frost, E. H., Savelkoul, P., Nicholson, B. & other authors (2008). Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. J Clin Microbiol 46, 431-437.
8. Kuijper, E. J., van den Berg, R. J. & Brazier, J. S. (2009). Comparison of molecular typing methods applied to Clostridium difficile. Methods Mol Biol 551, 159-171.
9. Marsh, J. W., O'Leary, M. M., Shutt, K. A., Pasculle, A. W., Johnson, S., Gerding, D. N., Muto, C. A. & Harrison, L. H. (2006). Multilocus variablenumber tandem-repeat analysis for investigation of Clostridium difficile transmission in hospitals. J ClinMicrobiol 44, 2558-2566.
10. Mulvey, M. R., Boyd, D. A., Gravel, D., Hutchinson, J., Kelly, S., McGeer, A., Moore, D., Simor, A., Suh, K. N. & other authors (2010). Hypervirulent Clostridium difficile strains in hospitalized patients, Canada. Emerg Infect Dis 16, 678-681.
11. Pillai, D. R., Longtin, J. & Low, D. E. (2010). Surveillance data on outbreaks of Clostridium difficile infection in Ontario, Canada, in 2008-2009. Clin Infect Dis 50, 1685-1686, author reply 1686.
12. Scaria, J., Ponnala, L., Janvilisri, T., Yan, W., Mueller, L. A. & Chang, Y. F. (2010). Analysis of ultra low genome conservation in Clostridium difficile. PLoS ONE 5, e15147.
13. Sebaihia, M., Wren, B. W., Mullany, P., Fairweather, N. F., Minton, N., Stabler, R., Thomson, N. R., Roberts, A. P., Cerden ̃ o-Ta ́ rraga A. M. & other authors (2006). The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet 38, 779-786.
14. Tanner, H. E., Hardy, K. J. & Hawkey, P. M. (2010). Coexistence ofmultiple multilocus variable-number tandem-repeat analysis subtypes of Clostridium difficile PCR ribotype 027 strains within fecal specimens. J Clin Microbiol 48, 985-987.
15. van den Berg, R. J., Schaap, I., Templeton, K. E., Klaassen, C. H. & Kuijper, E. J. (2007). Typing and subtyping of Clostridium difficile isolates by using multiple-locus variable-number tandem-repeat analysis. J Clin Microbiol 45, 1024-1028.