Infectious complications and soft tissue injury contribute to late amputation after severe lower extremity trauma

Journal of Trauma - Injury, Infection and Critical Care

Volumn 71, Issue SUPPL. 1, 2011, Pages

  Huh, Jeannie ^a   Stinner, Daniel J ^a   Burns, Travis C ^a   Hsu, Joseph R ^b  

^a BROOKE ARMY MEDICAL CENTER   (United States)

^b US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Combat; Delayed amputation; Late amputation; Limb salvage

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ADULT; ARTICLE; AUTOGRAFT; BATTLE INJURY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GRAFT FAILURE; HUMAN; LEG AMPUTATION; LIMB SALVAGE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; OPEN FRACTURE; OSTEOMYELITIS; PRIORITY JOURNAL; SOFT TISSUE INJURY; TIBIA FRACTURE;

ADOLESCENT; ADULT; AFGHAN CAMPAIGN 2001-; AMPUTATION; HUMANS; INJURY SEVERITY SCORE; IRAQ WAR, 2003 -; LEG INJURIES; LIMB SALVAGE; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TIBIAL FRACTURES; WOUND INFECTION; YOUNG ADULT;

EID: 79960394781     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e318221181d     Document Type: Article

References (25)

1. Owens BD, Kragh JF Jr, Wenke JC, Macaitis J, Wade CE, Holcomb JB. Combat wounds in Operation Iraqi Freedom and Operation Enduring Freedom. J Trauma. 2008;64:295-299. (Pubitemid 351640430)
2. Amputations. In: Emergency War Surgery. 3rd United States Revision. 2004:chap 25.
3. Harris AM, Althausen PL, Kellam J, et al. Complications following limb-threatening lower extremity trauma. J Orthop Trauma. 2009;23: 1-6.
4. Busse JW, Jacobs CL, Swiontkowski MF, Bosse MJ, Bhandari M; Evidence-Based Orthopaedic Trauma Working Group. Complex limb salvage or early amputation for severe lower-limb injury: a metaanalysis of observational studies. J Orthop Trauma. 2007;21:70-76. (Pubitemid 46071968)
5. Caudle RJ, Stern PJ. Severe open fractures of the tibia. J Bone Joint Surg Am. 1987;69:801-807. (Pubitemid 17162600)
6. Fairhurst MJ. The function of below-knee amputee versus the patient with salvaged grade III tibial fracture. Clin Orthop Relat Res. 1994;301: 227-232. (Pubitemid 24119278)
7. Georgiadis GM, Behrens FF, Joyce MJ, Earle AS, Simmons AL. Open tibial fractures with severe soft-tissue loss. Limb salvage compared with below-the-knee amputation. J Bone Joint Surg Am. 1993;75:1431-1441.
8. Dahl B, Andersson AP, Andersen M, Andersen GR, Ebskov LB, Reumert T. Functional and social long-term results after free tissue transfer to the lower extremity. Ann Plast Surg. 1995;34:372-375.
9. Stinner DJ, Burns TC, Kirk KL, Scoville CR, Ficke JR, Hsu JR; Late Amputation Study Team. Prevalence of late amputations during the current conflicts in Afghanistan and Iraq. Mil Med. 2010;175:1027-1029.
10. Ly TV, Travison TG, Castillo RC, Bosse MJ, MacKenzie EJ; LEAP Study Group. Ability of lower-extremity injury severity scores to predict functional outcome after limb salvage. J Bone Joint Surg Am. 2008;90: 1738-1743.
11. Brown KV, Ramasamy A, McLeod J, Stapley S, Clasper JC. Predicting the need for early amputation in ballistic mangled extremity injuries. J Trauma. 2009;66:S93-S97.
12. Court-Brown CM, McBirnie J. The epidemiology of tibial fractures. J Bone Joint Surg Br. 1995;77:417-421.
13. Smith DG, Castillo RC, MacKenzie EJ, et al. Functional outcomes of patients who have late amputations after trauma is significantly worse than for those who have early amputation. Presented at the Orthopaedic Trauma Association, October 9, 2003.
14. Muller ME, Nazarian S, Koch P, Schatzker J. The Comprehensive Classification of Fractures of Long Bones. New York: Springer; 1990.
15. Gustilo RB, Gruninger RP, Davis T. Classification of type III (severe) open fractures relative to treatment and results. Orthopedics. 1987;10: 1781-1788. (Pubitemid 18019357)
16. Bosse MJ, MacKenzie EJ, Kellam JF, et al. An analysis of outcomes of reconstruction or amputation after leg-threatening injuries. N Engl J Med. 2002;347:1924-1931. (Pubitemid 35429922)
17. MacKenzie EJ, Bosse MJ, Kellam JF, et al. Factors influencing the decision to amputate or reconstruct after high-energy lower extremity trauma. J Trauma. 2002;52:641-649. (Pubitemid 34437221)
18. MacKenzie EJ, Bosse MJ, Pollak AN, et al. Long-term persistence of disability following severe lower-limb trauma. Results of a seven-year follow-up. J Bone Joint Surg Am. 2005;87:1801-1809. (Pubitemid 41061201)
19. MacKenzie EJ, Bosse MJ. Factors influencing outcome following limbthreatening lower limb trauma: lessons learned from the Lower Extremity Assessment Project (LEAP). J Am Acad Orthop Surg. 2006;14:S205-S210.
20. Bondurant FJ, Cotler HB, Buckle R, Miller-Crotchett P, Browner BD. The medical and economic impact of severely injured lower extremities. J Trauma. 1988;28:1270-1273.
21. Thiagarajan P. Delayed amputation in lower limb trauma: an analysis of factors leading to delayed amputation. Ann Acad Med Singapore. 1999; 28:227-230.
22. Gajewski D, Granville R. The United States Armed Forces Amputee Patient Care Program. J Am Acad Orthop Surg. 2006;14:S183-S187.
23. Dougherty P. Transtibial amputees from the Vietnam War: twenty-eightyear follow-up. J Bone Joint Surg Am. 2001;83:383-389. (Pubitemid 32221568)
24. Stansbury LG, Lalliss SJ, Branstetter JG, Bagg MR, Holcomb JB. Amputations in U.S. military personnel in the current conflicts in Afghanistan and Iraq. J Orthop Trauma. 2008;22:43-46.
25. Stinner DJ, Burns TC, Kirk KL, Ficke JR. Return to duty rate of amputee soldiers in the current conflicts in Afghanistan and Iraq. J Trauma. 2010;20:1-4.