Functional characterization of seven γ-glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-alanine utilization in Pseudomonas aeruginosa PAO1

Journal of Bacteriology

Volumn 193, Issue 15, 2011, Pages 3923-3930

  Yao, Xiangyu ^a   He, Weiqing ^a,b   Lu, Chung Dar ^a,c  

^a GEORGIA STATE UNIVERSITY   (United States)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ALANINE; BETA GALACTOSIDASE; GAMMA GLUTAMYLPOLYAMINE SYNTHETASE; POLYAMINE; PUTRESCINE; SPERMIDINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; GENE; GENE LOCUS; IN VITRO STUDY; MUTATIONAL ANALYSIS; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PSEUDOMONAS AERUGINOSA; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; BETA-ALANINE; GENE EXPRESSION REGULATION, BACTERIAL; PEPTIDE SYNTHASES; POLYAMINES; PROMOTER REGIONS, GENETIC; PSEUDOMONAS AERUGINOSA;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 79960390406     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.05105-11     Document Type: Article

References (31)

1. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
2. Casero, R. A., and A. E. Pegg. 2009. Polyamine catabolism and disease. Biochem. J. 421:323-338.
3. Childs, A. C., D. J. Mehta, and E. W. Gerner. 2003. Polyamine-dependent gene expression. Cell. Mol. Life Sci. 60:1394-1406.
4. Chou, H. T., D. H. Kwon, M. Hegazy, and C. D. Lu. 2008. Transcriptome analysis of agmatine and putrescine catabolism in Pseudomonas aeruginosa PAO1. J. Bacteriol. 190:1966-1975.
5. Dasu, V. V., Y. Nakada, M. Ohnishi-Kameyama, K. Kimura, and Y. Itoh. 2006. Characterization and a role of Pseudomonas aeruginosa spermidine dehydrogenase in polyamine catabolism. Microbiology 152:2265-2272.
6. Farinha, M. A., and A. M. Kropinski. 1990. Construction of broad-hostrange plasmid vectors for easy visible selection and analysis of promoters. J. Bacteriol. 172:3496-3499.
7. Gambello, M. J., and B. H. Iglewski. 1991. Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression. J. Bacteriol. 173:3000-3009.
8. Ha, H. C., et al. 1998. The natural polyamine spermine functions directly as a free radical scavenger. Proc. Natl. Acad. Sci. U. S. A. 95:11140-11145.
9. Haas, D., B. W. Holloway, A. Schambock, and T. Leisinger. 1977. The genetic organization of arginine biosynthesis in Pseudomonas aeruginosa. Mol. Gen. Genet. 154:7-22.
10. Hoang, T. T., R. R. Karkhoff-Schweizer, A. J. Kutchma, and H. P. Schweizer. 1998. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212:77-86.
11. Huang, S. C., C. A. Panagiotidis, and E. S. Canellakis. 1990. Transcriptional effects of polyamines on ribosomal proteins and on polyamine-synthesizing enzymes in Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 87:3464-3468.
12. Ikai, H., and S. Yamamoto. 1997. Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii. J. Bacteriol. 179:5118-5125.
13. Ingram, C. U., et al. 2007. One-pot synthesis of amino-alcohols using a de-novo transketolase and beta-alanine: pyruvate transaminase pathway in Escherichia coli. Biotechnol. Bioeng. 96:559-569.
14. Jacobs, M. A., et al. 2003. Comprehensive transposon mutant library of Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U. S. A. 100:14339-14344.
15. Jann, A., H. Matsumoto, and D. Haas. 1988. The fourth arginine catabolic pathway of Pseudomonas aeruginosa. J. Gen. Microbiol. 134:1043-1053.
16. Khan, A. U., P. Di Mascio, M. H. Medeiros, and T. Wilson. 1992. Spermine and spermidine protection of plasmid DNA against single-strand breaks induced by singlet oxygen. Proc. Natl. Acad. Sci. U. S. A. 89:11428-11430.
17. Kurihara, S., et al. 2005. A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12. J. Biol. Chem. 280:4602-4608.
18. Kurihara, S., S. Oda, H. Kumagai, and H. Suzuki. 2006. Gamma-glutamylgamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12. FEMS Microbiol. Lett. 256:318-323.
19. Kurihara, S., et al. 2008. γ-Glutamylputrescine synthetase in the putrescine utilization pathway of Escherichia coli K-12. J. Biol. Chem. 283:19981-19990.
20. Kwon, D. H., and C. D. Lu. 2007. Polyamine effects on antibiotic susceptibility in bacteria. Antimicrob. Agents Chemother. 51:2070-2077.
21. Kwon, D. H., and C. D. Lu. 2006. Polyamines induce resistance to cationic peptide, aminoglycoside, and quinolone antibiotics in Pseudomonas aeruginosa PAO1. Antimicrob. Agents Chemother. 50:1615-1622.
22. Lee, J., et al. 2009. An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae. J. Biol. Chem. 284:9899-9907.
23. Li, C., and C. D. Lu. 2009. Arginine racemization by coupled catabolic and anabolic dehydrogenases. Proc. Natl. Acad. Sci. U. S. A. 106:906-911.
24. Li, C., and C. D. Lu. 2009. Unconventional integration of the bla gene from plasmid pIT2 during ISlacZ/hah transposon mutagenesis in Pseudomonas aeruginosa PAO1. Curr. Microbiol. 58:472-477.
25. Lu, C. D., Y. Itoh, Y. Nakada, and Y. Jiang. 2002. Functional analysis and regulation of the divergent spuABCDEFGH-spuI operons for polyamine uptake and utilization in Pseudomonas aeruginosa PAO1. J. Bacteriol. 184: 3765-3773.
26. Nakada, Y., Y. Jiang, T. Nishijyo, Y. Itoh, and C. D. Lu. 2001. Molecular characterization and regulation of the aguBA operon, responsible for agmatine utilization in Pseudomonas aeruginosa PAO1. J. Bacteriol. 183:6517-6524.
27. Revelles, O., M. Espinosa-Urgel, S. Molin, and J. L. Ramos. 2004. The davDT operon of Pseudomonas putida, involved in lysine catabolism, is induced in response to the pathway intermediate delta-aminovaleric acid. J. Bacteriol. 186:3439-3446.
28. Schweizer, H. D. 1993. Small broad-host-range gentamicin resistance gene cassettes for site-specific insertion and deletion mutagenesis. Biotechniques 15:831-834.
29. Tabor, C. W., and H. Tabor. 1985. Polyamines in microorganisms. Microbiol. Rev. 49:81-99.
30. Walters, D. R. 2003. Polyamines and plant disease. Phytochemistry 64:97-107.
31. Wortham, B. W., C. N. Patel, and M. A. Oliveira. 2007. Polyamines in bacteria: pleiotropic effects yet specific mechanisms. Adv. Exp. Med. Biol. 603:106-115.