Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies

Journal of Experimental Medicine

Volumn 208, Issue 7, 2011, Pages 1419-1433

  Rusert, Peter ^a   Krarup, Anders ^a   Magnus, Carsten ^b   Brandenberg, Oliver F ^a   Weber, Jacqueline ^a   Ehlert, Anna Katharina ^a   Regoes, Roland R ^b   Günthard, Huldrych F ^a   Trkola, Alexandra ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; NEUTRALIZING ANTIBODY; PROTEIN SUBUNIT;

ARTICLE; CONTROLLED STUDY; ELECTRON TOMOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; VIRUS ENVELOPE;

AMINO ACID SEQUENCE; ANTIBODIES, NEUTRALIZING; BASE SEQUENCE; CELL LINE; CROSS REACTIONS; DNA, VIRAL; EPITOPES; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MODELS, IMMUNOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY;

EID: 79960346105     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110196     Document Type: Article

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