Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 15, 2011, Pages 4581-4584

  Satish, K ^a   Vishnuvardhan, M V P S ^a   Lakshma Nayak, V ^a   Srihari, G ^a   Subrahamanyam, M ^a   Prabhakar Rao, T ^a   Ramakrishna, S ^a   Ravikumar, K ^a   Sridhar, B ^a   Marthanda Murthy, M ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Cytotoxicity; Diterpenoid quinonemethides; Pygmacopremna herbacea; Verbenaceae

Indexed keywords

11 HYDROXY 5,7,9,13 ABIETATETRAENE 2,12 DIONE; ACETIC ACID ETHYL ESTER; BHARANGIN; CYTOTOXIC AGENT; DITERPENOID; DOXORUBICIN; HEXANE; ISOBHARANGIN; NEOBHARANGIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN A 549; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CELL STRAIN PC 3; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; HELA CELL; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MALE; MEDICINAL PLANT; NUCLEAR OVERHAUSER EFFECT; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; PYGMACOPREMNA HERBACEA; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLEQUINONES; MOLECULAR CONFORMATION; PLANT ROOTS; VERBENACEAE;

VERBENACEAE;

EID: 79960346071     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.05.109     Document Type: Article

References (20)

1. A. Krishnamurthi The Wealth of India VIII 1969 Publication and Information Directorate, CSIR New Delhi
2. R.C. Nayer, S.N. Yognarsimha, and K. Subramanyam Indian J. Pharm. 38 1976 39
3. S.P. Ambasta The Useful Plants of India 1996 Publication and Information Directorate, CSIR New Delhi, India p. 489
4. G. Sandhya, K. Rajagopalan, and N. Chandrakumar Phytochemistry 27 1988 2249
5. W. Chen J. Nat. Prod. 52 1989 581
6. Q. Meng, N. Zhu, and W. Chen Phytochemistry 27 1988 1151
7. Q. Meng, and W. Chen Planta Med. 54 1988 48
8. A.V.B. Sankaram, M. Marthandamurthy, K. Bhaskraih, G.L. Narsimharao, M. Subramanyam, and J.N. Shoolery Tetrahedron Lett. 29 1988 245
9. A.V.B. Sankaram, K. Bhaskraih, M. Marthandamurthy, and M. Subramanyam Tetrahedron Lett. 30 1989 867
10. A.V.B. Sankaram, K. Bhaskraih, M. Marthandamurthy, and M. Subramanyam Tetrahedron Lett. 29 1988 4881
11. A.V.B. Sankaram, and M. Marthandamurthy Phytochemistry 30 1991 359
12. G. Srihari, M.V.P.S. Vishuvardhan, K. Satish, M. Subramanyam, T.V. Raju, T. Prabhakar, and M. Marthandamurthy Phytochem. Lett. 4 2011 109
13. M. Marthandamurthy, M. Subramanyam, K.V. Giridhar, and J. Annapurna J. Ethnopharmacol. 104 2006 290
14. N. Narayanan, P. Thirugnasambantham, S. Viswanathan, M. Kannappa Reddy, V. Vijayasekaran, and E. Sukumar Fitoterapia 71 2000 147
15. V.V. Lakshmi, S. Padma, and H. Polasa FEMS Microbiol. Lett. 57 1989 275
16. D. Karanatsios, J.S. Scarpa, and C.H. Eugster Helv. Chim. Acta 49 1966 1151
17. F. Simoes, A. Michavile, B. Rodriguez, M.C. Garcia Alwarez, and M. Hasan Phytochemistry 25 1986 755
18. T. Miyasi, P. Ruedi, and C.H. Eugster Helv. Chim. Acta 60 1977 2789
19. G.M. Sheldrick Acta Crystallogr., Sect. A 64 2008 112
20. < http://www.atcc.org/common/documents/pdf/30-1010k.pdf >.