Neonatal head ultrasound abnormalities in preterm infants and adolescent psychiatric disorders

Archives of General Psychiatry

Volumn 68, Issue 7, 2011, Pages 742-752

  Whitaker, Agnes H ^a,b   Feldman, Judith F ^a,b   Lorenz, John M ^a   McNicholas, Fiona ^c   Fisher, Prudence W ^a,b   Shen, Sa ^a,b   Pinto Martin, Jennifer ^d   Shaffer, David ^a,b   Paneth, Nigel ^e  

^a NewYork Presbyterian Hospital   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c Dublin Dental University Hospital   (Ireland)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADOLESCENT DISEASE; ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN VENTRICLE DILATATION; CHILD PSYCHIATRY; ECHOGRAPHY; FEMALE; HUMAN; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MENTAL DISEASE; NEWBORN DISEASE; OBSESSIVE COMPULSIVE DISORDER; PREMATURITY; SURVIVOR;

ADOLESCENT; ADOLESCENT PSYCHOLOGY; BRAIN INJURIES; ECHOENCEPHALOGRAPHY; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; MENTAL DISORDERS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 79960335034     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archgenpsychiatry.2011.62     Document Type: Article

References (100)

1. Pasamanick B, Rogers ME, Lilienfeld AM. Pregnancy experience and the development of behavior disorders in children. Am J Psychiatry. 1956;112 (8):613-618.
2. Weinberger DR, Hirsch SR. Schizophrenia as a neurodevelopmental disorder. In: Weinberger DR, Hirsch SR, eds. Schizophrenia. Cambridge, MA: Blackwell Science; 1995:293-323.
3. Peterson B, Leckman J, Cohen D. Tourette's syndrome: a genetically predisposed and an environmentally specified developmental psychopathology. In: Cicchetti D, Cohen D, eds. Developmental Psychopathology. New York, NY: Wiley; 1995:213-241.
4. Rutter M. Concepts of brain dysfunction syndromes. In: Rutter M, ed. Developmental Neuropsychiatry. New York, NY: Guilford Press; 1983:1-11.
5. Lewis DA, Levitt P. Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci. 2002;25:409-432. (Pubitemid 34748023)
6. Miller SP, Ferriero DM. From selective vulnerability to connectivity: insights from newborn brain imaging. Trends Neurosci. 2009;32(9):496-505.
7. Volpe JJ. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol. 2009;8(1):110-124.
8. Kinney HC. The encephalopathy of prematurity: one pediatric neuropathologist's perspective. Semin Pediatr Neurol. 2009;16(4):179-190.
9. Truwit CL, Barkovich AJ, Koch TK, Ferriero DM. Cerebral palsy: MR findings in 40 patients. AJNR Am J Neuroradiol. 1992;13(1):67-78.
10. Marín-Padilla M. Developmental neuropathology and impact of perinatal brain damage; III: gray matter lesions of the neocortex. J Neuropathol Exp Neurol. 1999;58(5):407-429. (Pubitemid 29220735)
11. Pierson CR, Folkerth RD, Billiards SS, Trachtenberg FL, Drinkwater ME, Volpe JJ, Kinney HC. Gray matter injury associated with periventricular leukomalacia in the premature infant. Acta Neuropathol. 2007;114(6):619-631. (Pubitemid 350142750)
12. Andiman SE, Haynes RL, Trachtenberg FL, Billiards SS, Folkerth RD, Volpe JJ, Kinney HC. The cerebral cortex overlying periventricular leukomalacia: analysis of pyramidal neurons. Brain Pathol. 2010;20(4):803-814.
13. Inder TE, Warfield SK, Wang H, Hüppi PS, Volpe JJ. Abnormal cerebral structure is present at term in premature infants. Pediatrics. 2005;115(2):286-294. (Pubitemid 43193809)
14. Boardman JP, Craven C, Valappil S, Counsell SJ, Dyet LE, Rueckert D, Aljabar P, Rutherford MA, Chew AT, Allsop JM, Cowan F, Edwards AD. A common neonatal image phenotype predicts adverse neurodevelopmental outcome in children born preterm. Neuroimage. 2010;52(2):409-414.
15. Smyser CD, Inder TE, Shimony JS, Hill JE, Degnan AJ, Snyder AZ, Neil JJ. Longitudinal analysis of neural network development in preterm infants. Cereb Cortex. 2010;20(12):2852-2862.
16. Ment LR, Hirtz D, Hüppi PS. Imaging biomarkers of outcome in the developing preterm brain. Lancet Neurol. 2009;8(11):1042-1055.
17. Volpe JJ. Encephalopathy of prematurity includes neuronal abnormalities. Pediatrics. 2005;116(1):221-225.
18. El-Dib M, Massaro AN, Bulas D, Aly H. Neuroimaging and neurodevelopmental outcome of premature infants. Am J Perinatol. 2010;27(10):803-818.
19. Hintz SR, O'Shea M. Neuroimaging and neurodevelopmental outcomes in preterm infants. Semin Perinatol. 2008;32(1):11-19. (Pubitemid 351174358)
20. Leijser LM, de Bruïne FT, Steggerda SJ, van der Grond J, Walther FJ, van Wezel-Meijler G. Brain imaging findings in very preterm infants throughout the neonatal period, I: incidences and evolution of lesions, comparison between ultrasound and MRI. Early Hum Dev. 2009;85(2):101-109.
21. Kostović I, Jovanov-Milosević N. The development of cerebral connections during the first 20-45 weeks' gestation. Semin Fetal Neonatal Med. 2006;11 (6):415-422. (Pubitemid 44666590)
22. Kostović I, Judas M. Correlation between the sequential ingrowth of afferents and transient patterns of cortical lamination in preterm infants. Anat Rec. 2002; 267(1):1-6. (Pubitemid 34465292)
23. Kostović I, Judas M. The development of the subplate and thalamocortical connections in the human foetal brain. Acta Paediatr. 2010;99(8):1119-1127.
24. Bradshaw JL, Sheppard DM. The neurodevelopmental frontostriatal disorders: evolutionary adaptiveness and anomalous lateralization. Brain Lang. 2000; 73(2):297-320. (Pubitemid 30408053)
25. Bystron I, Blakemore C, Rakic P. Developmental of the human cerebral cortex: Boulder committee revisited. Nat Rev Neurosci. 2008;9:110-122.
26. Kostovic I, Vasung L. Insights from in vitro fetal magnetic resonance imaging of cerebral development. Semin Perinatol. 2009;33(4):220-233.
27. Gressens P, Richelme C, Kadhim HJ, Gadisseux JF, Evrard P. The germinative zone produces the most cortical astrocytes after neuronal migration in the developing mammalian brain. Biol Neonate. 1992;61(1):4-24.
28. Evrard P, Gressens P, Volpe JJ. New concepts to understand the neurological consequences of subcortical lesions in the premature brain. Biol Neonate. 1992; 61(1):1-3.
29. Anstrom JA, Brown WR, Moody DM, Thore CR, Challa VR, Block SM. Subependymal veins in premature neonates: implications for hemorrhage. Pediatr Neurol. 2004;30(1):46-53. (Pubitemid 38102317)
30. Kuban K, Sanocka U, Leviton A, Allred EN, Pagano M, Dammann O, Share J, Rosenfeld D, Abiri M, DiSalvo D, Doubilet P, Kairam R, Kazam E, Kirpekar M, Schonfeld S; Developmental Epidemiology Network. White matter disorders of prematurity: association with intraventricular hemorrhage and ventriculomegaly. J Pediatr. 1999;134(5):539-546. (Pubitemid 30180590)
31. Paneth N, Rudelli R, Kazam E, Monte WA. Brain Damage in the Preterm Infant. London, England: MacKeith Press; 1994.
32. Ajayi-Obe M, Saeed N, Cowan FM, Rutherford MA, Edwards AD. Reduced development of cerebral cortex in extremely preterm infants. Lancet. 2000; 356(9236):1162-1163.
33. Vasileiadis GT, Gelman N, Han VKM, Williams LA, Mann R, Bureau Y, Thompson RT. Uncomplicated intraventricular hemorrhage is followed by reduced cortical volume at near-term age. Pediatrics. 2004;114(3):e367-e372. doi:10.1542/peds.2004-0500. (Pubitemid 41529504)
34. Ross G, Tesman J, Auld PAM, Nass R. Effects of subependymal and mild intraventricular lesions on visual attention and memory in premature infants. Dev Psychol. 1992;28(6):1067-1074.
35. Ross G, Boatright S, Auld PA, Nass R. Specific cognitive abilities in 2-year-old children with subependymal and mild intraventricular hemorrhage. Brain Cogn. 1996;32(1):1-13. (Pubitemid 27005166)
36. Patra K, Wilson-Costello D, Taylor HG, Mercuri-Minich N, Hack M. Grades I-II intraventricular hemorrhage in extremely low birth weight infants: effects on neurodevelopment. J Pediatr. 2006;149(2):169-173. (Pubitemid 44128556)
37. Pinto-Martin JA, Riolo S, Cnaan A, Holzman C, Susser MW, Paneth N. Cranial ultrasound prediction of disabling and nondisabling cerebral palsy at age two in a low birth weight population [published correction appears in Pediatrics. 2001;108(2):238]. Pediatrics. 1995;95(2):249-254.
38. Pinto-Martin JA, Whitaker AH, Feldman JF, Van Rossem R, Paneth N. Relation of cranial ultrasound abnormalities in low-birthweight infants to motor or cognitive performance at ages 2, 6, and 9 years. Dev Med Child Neurol. 1999; 41(12):826-833.
39. Whitaker AH, Feldman JF, Lorenz JM, Shen S, McNicholas F, Nieto M, McCulloch D, Pinto-Martin JA, Paneth N. Motor and cognitive outcomes in nondisabled low-birth-weight adolescents: early determinants. Arch Pediatr Adolesc Med. 2006;160(10):1040-1046. (Pubitemid 44520634)
40. Whitaker AH, Feldman JF, Van Rossem R, Schonfeld IS, Pinto-Martin JA, Torre C, Blumenthal SR, Paneth NS. Neonatal cranial ultrasound abnormalities in low birth weight infants: relation to cognitive outcomes at age six. Pediatrics. 1996; 98(4):719-729.
41. Ganat Y, Soni S, Chacon M, Schwartz ML, Vaccarino FM. Chronic hypoxia upregulates fibroblast growth factor ligands in the perinatal brain and induces fibroblast growth factor-responsive radial glial cells in the sub-ependymal zone. Neuroscience. 2002;112(4):977-991. (Pubitemid 34667060)
42. Vaccarino FM, Ment LR. Injury and repair in developing brain. Arch Dis Child Fetal Neonatal Ed. 2004;89(3):F190-F192. (Pubitemid 38570142)
43. Inder TE. Neurodevelopmental impact of low-grade intraventricular hemorrhage in very preterm infants. J Pediatr. 2006;149(2):152-154. (Pubitemid 44128563)
44. Back SA, Riddle A, McClure MM. Maturation-dependent vulnerability of perinatal white matter in premature birth. Stroke. 2007;38(2)(suppl):724-730. (Pubitemid 46184249)
45. Kaindl AM, Favrais G, Gressens P. Molecular mechanisms involved in injury to the preterm brain. J Child Neurol. 2009;24(9):1112-1118.
46. Banker BQ, Larroche JC. Periventricular leukomalacia of infancy: a form of neonatal anoxic encephalopathy. Arch Neurol. 1962;7:386-410.
47. Leviton A, Gressens P. Neuronal damage accompanies perinatal white-matter damage. Trends Neurosci. 2007;30(9):473-478. (Pubitemid 47374834)
48. Boardman JP, Counsell SJ, Rueckert D, Kapellou O, Bhatia KK, Aljabar P, Hajnal J, Allsop JM, Rutherford MA, Edwards AD. Abnormal deep grey matter development following preterm birth detected using deformation-based morphometry. Neuroimage. 2006;32(1):70-78.
49. Lin Y, Okumura A, Hayakawa F, Kato K, Kuno T, Watanabe K. Quantitative evaluation of thalami and basal ganglia in infants with periventricular leukomalacia. Dev Med Child Neurol. 2001;43(7):481-485. (Pubitemid 32651795)
50. Srinivasan L, Dutta R, Counsell SJ, Allsop JM, Boardman JP, Rutherford MA, Edwards AD. Quantification of deep gray matter in preterm infants at term-equivalent age using manual volumetry of 3-tesla magnetic resonance images. Pediatrics. 2007;119(4):759-765. (Pubitemid 46556675)
51. Taylor HG, Minich N, Bangert B, Filipek PA, Hack M. Long-term neuropsychological outcomes of very low birth weight: associations with early risks for periventricular brain insults. J Int Neuropsychol Soc. 2004;10(7):987-1004.
52. Pinto-Martin J, Paneth N, Witomski T, Stein I, Schonfeld S, Rosenfeld D, Rose W, Kazam E, Kairam R, Katsikiotis V, Susser M. The central New Jersey neonatal brain haemorrhage study: design of the study and reliability of ultrasound diagnosis. Paediatr Perinat Epidemiol. 1992;6(2):273-284.
53. Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr. 1978;92(4):529-534. (Pubitemid 8293290)
54. Leviton A, Kuban K, Paneth N. Intraventricular haemorrhage grading scheme: time to abandon? Acta Paediatr. 2007;96(9):1254-1256. (Pubitemid 47300682)
55. Whitaker AH, Van Rossem R, Feldman JF, Schonfeld IS, Pinto-Martin JA, Tore C, Shaffer D, Paneth N. Psychiatric outcomes in low-birth-weight children at age 6 years: relation to neonatal cranial ultrasound abnormalities. Arch Gen Psychiatry. 1997;54(9):847-856. (Pubitemid 27383312)
56. Kuban KC, Allred EN, Dammann O, Pagano M, Leviton A, Share J, Abiri M, Di Salvo D, Doubilet P, Kairam R, Kazam E, Kirpekar M, Rosenfeld DL, Sanocka UM, Schonfeld SM; Developmental Epidemiology Network. Topography of cerebral white-matter disease of prematurity studied prospectively in 1607 very-low-birthweight infants. J Child Neurol. 2001;16(6):401-408. (Pubitemid 32631734)
57. O'Shea TM, Kuban KC, Allred EN, Paneth N, Pagano M, Dammann O, Bostic L, Brooklier K, Butler S, Goldstein DJ, Hounshell G, Keller C, McQuiston S, Miller A, Pasternak S, Plesha-Troyke S, Price J, Romano E, Solomon KM, Jacobson A, Westra S, Leviton A; Extremely Low Gestational Age Newborns Study Investigators. Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age children. Pediatrics. 2008; 122(3):e662-e669. doi:10.1542/peds.2008-0594.
58. Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME. NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry. 2000;39(1):28-38. (Pubitemid 30029897)
59. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association; 2000.
60. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association; 1994.
61. SPSS for Windows [computer program]. Version 17.0. Chicago, IL: SPSS, Inc; 2009.
62. Jöreskog KG, Sörbom D. Lisrel 8: User's Reference Guide. Chicago, IL: Scientific Software International; 1996.
63. Riley GD. Riley Motor Problems Inventory Manual. Los Angeles, CA: Western Psychological Services; 1976.
64. Indredavik MS, Skranes JS, Vik T, Heyerdahl S, Romundstad P, Myhr GE, Brubakk AM. Low-birth-weight adolescents: psychiatric symptoms and cerebral MRI abnormalities. Pediatr Neurol. 2005;33(4):259-266. (Pubitemid 41382504)
65. Skranes J, Vangberg TR, Kulseng S, Indredavik MS, Evensen KAI, Martinussen M, Dale AM, Haraldseth O, Brubakk AM. Clinical findings and white matter abnormalities seen on diffusion tensor imaging in adolescents with very low birth weight. Brain. 2007;130(pt 3):654-666. (Pubitemid 46410747)
66. Stewart AL, Rifkin L, Amess PN, Kirkbride V, Townsend JP, Miller DH, Lewis SW, Kingsley DPE, Moseley IF, Foster O, Murray RM. Brain structure and neurocognitive and behavioural function in adolescents who were born very preterm. Lancet. 1999;353(9165):1653-1657. (Pubitemid 29224521)
67. Johnson S, Hollis C, Kochhar P, Hennessy E, Wolke D, Marlow N. Psychiatric disorders in extremely preterm children: longitudinal finding at age 11 years in the EPI-Cure study. J Am Acad Child Adolesc Psychiatry. 2010;49(5):453-463.e1.
68. Luu TM, Ment LR, Schneider KC, Katz KH, Allan WC, Vohr BR. Lasting effects of preterm birth and neonatal brain hemorrhage at 12 years of age. Pediatrics. 2009;123(3):1037-1044.
69. Achenbach TM, Rescorla LA. Manual for the ASEBA School-Age Forms and Profiles. Burlington: University of Vermont, Research Center for Children, Youth, & Families; 2001.
70. Hille ET, den Ouden AL, Saigal S, Wolke D, Lambert M, Whitaker A, Pinto-Martin JA, Hoult L, Meyer R, Feldman JF, Verloove-Vanhorick SP, Paneth N. Behavioural problems in children who weigh 1000 g or less at birth in four countries. Lancet. 2001;357(9269):1641-1643. (Pubitemid 32568235)
71. Hudziak JJ, Althoff RR, Stanger C, van Beijsterveldt CE, Nelson EC, Hanna GL, Boomsma DI, Todd RD. The Obsessive Compulsive Scale of the Child Behavior Checklist predicts obsessive-compulsive disorder: a receiver operating characteristic curve analysis. J Child Psychol Psychiatry. 2006;47(2):160-166.
72. Halperin JM, Schulz KP. Revisiting the role of the prefrontal cortex in the pathophysiology of attention-deficit/hyperactivity disorder. Psychol Bull. 2006; 132(4):560-581. (Pubitemid 44212071)
73. Huyser C, Veltman DJ, de Haan E, Boer F. Paediatric obsessive-compulsive disorder, a neurodevelopmental disorder? evidence from neuroimaging. Neurosci Biobehav Rev. 2009;33(6):818-830.
74. Gerard E, Peterson BS. Developmental processes and brain imaging studies in Tourette syndrome. J Psychosom Res. 2003;55(1):13-22. (Pubitemid 36949565)
75. Maia TV, Cooney RE, Peterson BS. The neural bases of obsessive-compulsive disorder in children and adults. Dev Psychopathol. 2008;20(4):1251-1283.
76. Qiu A, Crocetti D, Adler M, Mahone EM, Denckla MB, Miller MI, Mostofsky SH. Basal ganglia volume and shape in children with attention deficit hyperactivity disorder. Am J Psychiatry. 2009;166(1):74-82.
77. Silk TJ, Vance A, Rinehart N, Bradshaw JL, Cunnington R. Structural development of the basal ganglia in attention deficit hyperactivity disorder: a diffusion tensor imaging study. Psychiatry Res. 2009;172(3):220-225.
78. Stanley JA, Kipp H, Greisenegger E, MacMaster FP, Panchalingam K, Keshavan MS, Bukstein OG, Pettegrew JW. Evidence of developmental alterations in cortical and subcortical regions of children with attention-deficit/ hyperactivity disorder: a multivoxel in vivo phosphorus 31 spectroscopy study. Arch Gen Psychiatry. 2008;65(12):1419-1428.
79. Toft PB. Prenatal and perinatal striatal injury: a hypothetical cause of attention-deficit-hyperactivity disorder? Pediatr Neurol. 1999;21(3):602-610. (Pubitemid 29460992)
80. Marsh R, Alexander GM, Packard MG, Zhu H, Wingard JC, Quackenbush G, Peterson BS. Habit learning in Tourette syndrome: a translational neuroscience approach to a developmental psychopathology. Arch Gen Psychiatry. 2004; 61(12):1259-1268. (Pubitemid 39602842)
81. Marsh R, Zhu H, Schultz RT, Quackenbush G, Royal J, Skudlarski P, Peterson BS. A developmental fMRI study of self-regulatory control. Hum Brain Mapp. 2006;27(11):848-863. (Pubitemid 44684998)
82. Marsh R, Zhu H, Wang Z, Skudlarski P, Peterson BS. A developmental fMRI study of self-regulatory control in Tourette's syndrome. Am J Psychiatry. 2007; 164(6):955-966. (Pubitemid 46972913)
83. Marsh R, Gerber AJ, Peterson BS. Neuroimaging studies of normal brain development and their relevance for understanding childhood neuropsychiatric disorders. J Am Acad Child Adolesc Psychiatry. 2008;47(11):1233-1251.
84. Matsuo K, Rosenberg DR, Easter PC, MacMaster FP, Chen HH, Nicoletti M, Caetano SC, Hatch JP, Soares JC. Striatal volume abnormalities in treatment-naïve patients diagnosed with pediatric major depressive disorder. J Child Adolesc Psychopharmacol. 2008;18(2):121-131. (Pubitemid 351591437)
85. Forbes EE, Hariri AR, Martin SL, Silk JS, Moyles DL, Fisher PM, Brown SM, Ryan ND, Birmaher B, Axelson DA, Dahl RE. Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder. Am J Psychiatry. 2009;166(1):64-73.
86. Cunningham MG, Bhattacharyya S, Benes FM. Amygdalo-cortical sprouting continues into early adulthood: implications for the development of normal and abnormal function during adolescence. J Comp Neurol. 2002;453(2):116-130. (Pubitemid 35155051)
87. Ulfig N. Ganglionic eminence of the human fetal brain - new vistas. Anat Rec. 2002;267(3):191-195. (Pubitemid 34742317)
88. Ulfig N, Setzer M, Bohl J. Ontogeny of the human amygdala. Ann N Y Acad Sci. 2003;985:22-33. (Pubitemid 36521102)
89. Rosenberg DR, Keshavan MS, O'Hearn KM, Dick EL, Bagwell WW, Seymour AB, Montrose DM, Pierri JN, Birmaher B. Frontostriatal measurement in treatmentnaive children with obsessive-compulsive disorder. Arch Gen Psychiatry. 1997; 54(9):824-830. (Pubitemid 27383308)
90. Szeszko PR, MacMillan S, McMeniman M, Chen S, Baribault K, Lim KO, Ivey J, Rose M, Banerjee SP, Bhandari R, Moore GJ, Rosenberg DR. Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessive-compulsive disorder. Am J Psychiatry. 2004;161(6):1049-1056. (Pubitemid 38735991)
91. Woolley J, Heyman I, Brammer M, Frampton I, McGuire PK, Rubia K. Brain activation in paediatric obsessive compulsive disorder during tasks of inhibitory control. Br J Psychiatry. 2008;192(1):25-31. (Pubitemid 351183157)
92. Graybiel AM, Rauch SL. Toward a neurobiology of obsessive-compulsive disorder. Neuron. 2000;28(2):343-347.
93. Gilmore JH, Smith LC, Wolfe HM, Hertzberg BS, Smith JK, Chescheir NC, Evans DD, Kang C, Hamer RM, Lin W, Gerig G. Prenatal mild ventriculomegaly predicts abnormal development of the neonatal brain. Biol Psychiatry. 2008; 64:1069-1076.
94. Robbins TW. The case of frontostriatal dysfunction in schizophrenia. Schizophr Bull. 1990;16(3):391-402.
95. Andreasen NC, Flashman L, Flaum M, Arndt S, Swayze V II, O'Leary DS, Ehrhardt JC, Yuh WT. Regional brain abnormalities in schizophrenia measured with magnetic resonance imaging. JAMA. 1994;272(22):1763-1769.
96. Beasley CL, Dwork AJ, Rosoklija G, Mann JJ, Mancevski B, Jakovski Z, Davceva N, Tait AR, Straus SK, Honer WG. Metabolic abnormalities in fronto-striatal-thalamic white matter tracts in schizophrenia. Schizophr Res. 2009;109(1-3): 159-166.
97. Rapoport JL, Addington AM, Frangou S, Psych MR. The neurodevelopmental model of schizophrenia: update 2005. Mol Psychiatry. 2005;10(5):434-449.
98. Morioka T, Hashiguchi K, Nagata S, Miyagi Y, Mihara F, Hikino S, Tsukimori K, Sasaki T. Fetal germinal matrix and intraventricular hemorrhage. Pediatr Neurosurg. 2006;42(6):354-361. (Pubitemid 44597727)
99. Limperopoulos C, Bassan H, Gauvreau K, Robertson RL Jr, Sullivan NR, Benson CB, Avery L, Stewart J, Soul JS, Ringer SA, Volpe JJ, duPlessis AJ. Does cerebellar injury in premature infants contribute to the high prevalence of long-term cognitive, learning, and behavioral disability in survivors? Pediatrics. 2007;120(3):584-593. (Pubitemid 47358302)
100. Rutter M, Graham P, Yule W. A Neuropsychiatric Study in Childhood: Clinics in Developmental Medicine. London, England: Heinemann/Spastics International Medical Publications; 1970. Reports 35/36.