Cell-based therapy for RDEB: How does it work

Journal of Investigative Dermatology

Volumn 131, Issue 8, 2011, Pages 1597-1599

  Uitto, Jouni ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBRIL; COLLAGEN TYPE 7; HEPARIN BINDING EPIDERMAL GROWTH FACTOR;

ALLOGENEIC STEM CELL TRANSPLANTATION; BONE MARROW TRANSPLANTATION; CELL THERAPY; DERMOEPIDERMAL JUNCTION; EPIDERMOLYSIS BULLOSA DYSTROPHICA; HUMAN; KERATINOCYTE; MYELOABLATIVE CONDITIONING; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SKIN FIBROBLAST; THERAPY EFFECT; TREATMENT OUTCOME;

EID: 79960304558     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.125     Document Type: Note

References (13)

1. Bruckner-Tuderman L, Mc Grath JA, Robinson EC et al. (2010) Animal models of epidermolysis bullosa: update 2010. J Invest Dermatol 130:1485-8
2. Chung HJ, Uitto J (2010) Type VII collagen: the anchoring fibril protein at fault in dystrophic epidermolysis bullosa. Dermatol Clin 28:93-105
3. Fine JD, Eady RA, Bauer EA et al. (2008) The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB. J Am Acad Dermatol 58:931-50
4. Kiuru M, Itoh M, Cairo MS et al. (2010) Bone marrow stem cell therapy for recessive dystrophic epidermolysis bullosa. Dermatol Clin 28:371-82
5. Nagy N, Almaani N, Tanaka A et al. (2011) HB-EGF induces COL7A1 expression in keratinocytes and fibroblasts: possible mechanism underlying allogeneic fibroblast therapy in recessive dystrophic epidermolysis bullosa. J Invest Dermatol 131:1771-4
6. Ortiz-Urda S, Lin Q, Green CL et al. (2003) njection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. J Clin Invest 111:251-5 (Pubitemid 36105924)
7. Tolar J, Xia L, Riddle MJ et al. (2011) Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa. J Invest Dermatol 131:848-56
8. Uitto J (2011) Regenerative medicine for skin disease: i PS cells to the rescue. J Invest Dermatol 131:812-4
9. Uitto J, Mc Grath JA, Rodeck U et al. (2010) Progress in epidermolysis bullosa research: toward treatment and cure. J Invest Dermatol 130:1778-84
10. Varki R, Sadowski S, Uitto J et al. (2007) Epidermolysis bullosa. II. Type VII collagen mutations and phenotype-genotype correlations in the dystrophic subtypes. J Med Genet 44:181-92 (Pubitemid 46580527)
11. Wagner JE, Ishida-Yamamoto A, Mc Grath JA et al. (2010) Bone marrow transplantation for recessive dystrophic epidermolysis bullosa. N Engl J Med 363:629-39
12. Wong T, Gammon L, Liu J et al. (2008) Potential of fibroblast cell therapy for recessive dystrophic epidermolysis bullosa. J Invest Dermatol 128:2179-89
13. Woodley DT, Remington J, Huang Y et al. (2007) ntravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing. Mol Ther 15:628-35