Structural and functional profiling of the human histone methyltransferase SMYD3

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Foreman, Kenneth W ^a,g   Brown, Mark ^b,h   Park, Frances ^c   Emtage, Spencer ^d   Harriss, June ^b   Das, Chhaya ^b   Zhu, Li ^b   Crew, Andy ^a   Arnold, Lee ^e   Shaaban, Salam ^f   Tucker, Philip ^b  

^a OSI PHARMACEUTICALS INC   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c AltheaDx Inc   (United States)

^d ELI LILLY AND COMPANY   (United States)

^e Discover Elucidations LLC   (United States)

^f ABBOTT LABORATORIES   (United States)

^g Coferon Inc ^*  (United States)

^h Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE SMYD1; HISTONE METHYLTRANSFERASE SMYD2; HISTONE METHYLTRANSFERASE SMYD3; HISTONE METHYLTRANSFERASE SMYD4; HISTONE METHYLTRANSFERASE SMYD5; UNCLASSIFIED DRUG; ADENOSINE; DRUG DERIVATIVE; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; SINEFUNGIN; SMYD3 PROTEIN, HUMAN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE EXPRESSION PROFILING; HISTONE METHYLATION; HUMAN; HUMAN CELL; MUTAGENESIS; NUCLEOTIDE SEQUENCE; POINT MUTATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; BINDING SITE; CHEMISTRY; MALE; METABOLISM; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ADENOSINE; BINDING SITES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; MALE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960295875     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022290     Document Type: Article

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