Methamphetamine users show greater than normal age-related cortical gray matter loss

Addiction

Volumn 106, Issue 8, 2011, Pages 1474-1483

  Nakama, Helenna ^a   Chang, Linda ^a   Fein, George ^b   Shimotsu, Ryan ^b   Jiang, Caroline S ^a   Ernst, Thomas ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b Neurobehavioral Research Inc   (United States)

Author keywords

Aging; Cortex; Imaging; Methamphetamine; Neuroimaging; Stimulants

Indexed keywords

CENTRAL STIMULANT AGENT; METHAMPHETAMINE; STREET DRUG;

ADOLESCENT; ADULT; AGE; AGING; ARTICLE; BLOOD PRESSURE; BRAIN CORTEX; CROSS-SECTIONAL STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DRUG ABUSE; DRUG EFFECT; FEMALE; HUMAN; IMAGE PROCESSING; MALE; METHODOLOGY; MIDDLE AGED; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY;

ADOLESCENT; ADULT; AGE FACTORS; AGING; AMPHETAMINE-RELATED DISORDERS; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM STIMULANTS; CEREBRAL CORTEX; CROSS-SECTIONAL STUDIES; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; METHAMPHETAMINE; MIDDLE AGED; NEUROIMAGING; STREET DRUGS; YOUNG ADULT;

EID: 79960241605     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/j.1360-0443.2011.03433.x     Document Type: Article

References (52)

1. Rawson R. A., Condon T. P. Why do we need an addiction supplement focused on methamphetamine? Addiction 2007; 102: 1-4.
2. Substance Abuse and Mental Health Services Administration (SAMHSA). SAaMHSA: the National Survey on Drug Use and Health Report, MD, USA Office of Applied Studies; 2005.
3. United Nations Office of Drug and Crime. World drug report. 2008; 153. New York, USA: United Nations Publications.
4. Report DaASISD. Smoked Methamphetamine/Amphetamines: 1992-2002. Edited by Services USDOHAH, Administration SAaMHS, Studies OoA; 2005. Available at: (accessed 27 April 2011; archived by Webcite at).
5. Newton T. F., De La Garza R. II, Kalechstein A. D., Nestor L. Cocaine and methamphetamine produce different patterns of subjective and cardiovascular effects. Pharmacol Biochem Behav 2005; 82: 90-7.
6. Zweben J. E., Cohen J. B., Christian D., Galloway G. P., Salinardi M., Parent D. etal. Psychiatric symptoms in methamphetamine users. Am J Addict 2004; 13: 181-90.
7. Semple S. J., Zians J., Grant I., Patterson T. L. Methamphetamine use, impulsivity, and sexual risk behavior among HIV-positive men who have sex with men. J Addict Dis 2006; 25: 105-14.
8. McKetin R., McLaren J., Lubman D. I., Hides L. The prevalence of psychotic symptoms among methamphetamine users. Addiction 2006; 101: 1473-8.
9. McGregor C., Srisurapanont M., Jittiwutikarn J., Laobhripatr S., Wongtan T., White J. M. The nature, time course and severity of methamphetamine withdrawal. Addiction 2005; 100: 1320-9.
10. Glasner-Edwards S., Mooney L. J., Marinelli-Casey P., Hillhouse M., Ang A., Rawson R. Clinical course and outcomes of methamphetamine-dependent adults with psychosis. J Subst Abuse Treat 2008; 35: 445-50.
11. Nakama H., Chang L., Cloak C., Jiang C., Alicata D., Haning W. Association between psychiatric symptoms and craving in methamphetamine users. Am J Addict 2008; 17: 441-6.
12. Tata D. A., Yamamoto B. K. Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction. Addiction 2007; 102: 49-60.
13. Berman S., O'Neill J., Fears S., Bartzokis G., London E. D. Abuse of amphetamines and structural abnormalities in the brain. Ann NY Acad Sci 2008; 1141: 195-220.
14. Zhu J., Xu W., Angulo J. Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice. Neuroscience 2006; 140: 607-22.
15. Harvey D. C., Lacan G., Melegan W. P. Regional heterogeneity of dopaminergic deficits in vervet monkey striatum and substantia nigra after methamphetamine exposure. Exp Brain Res 2000; 133: 349-58.
16. Berman S. M., Voytek B., Mandelkern M. A., Hassid B. D., Isaacson A., Monterosso J. etal. Changes in cerebral glucose metabolism during early abstinence from chronic methamphetamine abuse. Mol Psychiatry 2008; 13: 897-908.
17. Volkow N., Chang L., Wang G., Fowler J., Ding Y., Sedler M. etal. Low level of brain dopamine d(2) receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex. Am J Psychiatry 2001; 158: 2015-21.
18. Thompson P., Hayashi K., Simon S., Geaga J., Hong M., Sui Y. etal. Structural abnormalities in the brains of human subjects who use methamphetamine. J Neurosci 2004; 24: 6028-36.
19. Chung A., Lyoo I. K., Kim S. J., Hwang J., Bae S. C., Sung Y. H. etal. Decreased frontal white-matter integrity in abstinent methamphetamine abusers. Int J Neuropsychopharmacol 2007; 10: 765-75.
20. Chang L., Cloak C., Patterson K., Grob C., Miller E. N., Ernst T. Enlarged striatum in abstinent methamphetamine abusers: a possible compensatory response. Biol Psychiatry 2005; 57: 967-74.
21. Ernst T., Chang L., Leonido-Yee M., Speck O. Evidence for long-term neurotoxicity associated with methamphetamine abuse: a 1H MRS study. Neurology 2000; 54: 1344-9.
22. Bartzokis G., Beckson M., Lu P. H., Edwards N., Rapoport R., Wiseman E. etal. Age-related brain volume reductions in amphetamine and cocaine addicts and normal controls: implications for addiction research. Psychiatry Res 2000; 98: 93-102.
23. Bartzokis G., Beckson M., Lu P. H., Edwards N., Bridge P., Mintz J. Brain maturation may be arrested in chronic cocaine addicts. Biol Psychiatry 2002; 51: 605-11.
24. Pfefferbaum A., Sullivan E. V., Rosenbloom M. J., Mathalon D. H., Lim K. O. A controlled study of cortical grey matter and ventricular changes in alcoholic men over a 5-year interval. Arch Gen Psychiatry 1998; 55: 905-12.
25. Fein G., Shimotsu R., Chu R., Barakos J. Parietal grey matter volume loss is related to spatial processing deficits in long-term abstinent alcoholic men. Alcohol Clin Exp Res 2009; 33: 1806-14.
26. Brett M. The MNI brain and the Talairach atlas. 1999. Available from (accessed 27 April 2011; archived by Webcite at).
27. Fein G., Shimotsu R., Di Sclafani V., Barakos J., Harper C. Increased white matter signal hyperintensities in long-term abstinent alcoholics compared with nonalcoholic controls. Alcohol Clin Exp Res 2009; 33: 70-8.
28. Simes R. J. An improved Bonferroni procedure for multiple tests of significance. Biometrika 1986; 73: 751-4.
29. Ge Y., Grossman R. I., Babb J. S., Rabin M. L., Mannon L. J., Kolson D. L. Age-related total grey matter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis. Am J Neuroradiol 2002; 23: 1327-33.
30. Raz N., Lindenberger U., Rodrigue K. M., Kennedy K. M., Head D., Williamson A. etal. Regional brain changes in aging healthy adults: general trends, individual differences and modifiers. Cereb Cortex 2005; 15: 1676-89.
31. Terry R., DeTeresa R., Hansen L. Neocortical cell counts in normal human adult aging. Ann Neurol 1987; 21: 530-9.
32. Raji C. A., Lopez O. L., Kuller L. H., Carmichael O. T., Becker J. T. Age, Alzheimer disease, and brain structure. Neurology 2009; 73: 1879-1905.
33. Raz N., Gunning F. M., Head D., Dupuis J. H., McQuain J., Briggs S. D. etal. Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal grey matter. Cereb Cortex 1997; 7: 268-82.
34. Smith C. D., Chebrolu H., Wekstein D. R., Schmitt F. A., Jicha G. A., Cooper G. etal. Brain structural alterations before mild cognitive impairment. Neurology 2007; 68: 1268-73.
35. Wang L., Goldstein F. C., Veledar E., Levey A. I., Lah J. J., Meltzer C. C. etal. Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor imaging. Am J Neuroradiol 2009; 269: 218-21.
36. Grady C. L., McIntosh A. R., Horwitz B., Maisog J. M., Ungerleider L. G., Mentis M. J. etal. Age-related reductions in human recognition memory due to impaired encoding. Science 1995; 269: 218-21.
37. Grady C. L., Maisog J. M., Horwitz B., Ungerleider L. G., Mentis M. J., Salerno J. A. etal. Age-related changes in cortical blood flow activation during visual processing of faces and location. J Neurosci 1994; 14: 1450-62.
38. Ohnishi T., Matsuda H., Tabira T., Asada T., Uno M. Changes in brain morphology in Alzheimer disease and normal aging: is Alzheimer disease an exaggerated aging process? Am J Neuroradiol 2001; 22: 1680-5.
39. Apostolova L. G., Dutton R. A., Dinov I. D., Hayashi K. M., Toga A. W., Cummings J. L. etal. Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps. Arch Neurol 2006; 63: 693-9.
40. Du A. T., Schuff N., Zhu X. P., Jagust W. J., Miller B. L., Reed B. R. etal. Atrophy rates of entorhinal cortex in AD and normal aging. Neurology 2003; 60: 481-6.
41. Fein G., Di Sclafani V. Cerebral reserve capacity: implications for alcohol and drug abuse. Alcohol 2004; 32: 63-7.
42. Onitsuka T., McCarley R. W., Kuroki N., Dickey C. C., Kubicki M., Demeo S. S. etal. Occipital lobe grey matter volume in male patients with chronic schizophrenia: a quantitative MRI study. Schizophr Res 2007; 92: 197-206.
43. Lappin J. M., Morgan K., Morgan C., Hutchison G., Chitnis X., Suckling J. etal. Grey matter abnormalities associated with duration of untreated psychosis. Schizophr Res 2006; 83: 145-53.
44. Takahashi T., Wood S. J., Yung A. R., Soulsby B., McGorry P. D., Suzuki M. etal. Progressive grey matter reduction of the superior temporal gyrus during transition to psychosis. Arch Gen Psychiatry 2009; 66: 366-76.
45. Mahoney J. J. 3rd, Kalechstein A. D., De La Garza R. 2nd, Newton T. F. Presence and persistence of psychotic symptoms in cocaine- versus methamphetamine-dependent participants. Am J Addict 2008; 17: 83-98.
46. Jernigan T., Gamst A., Archibald S., Fennema-Notestine C., Mindt M., Marcotte T. etal. Effects of methamphetamine dependence and HIV infection on cerebral morphology. Am J Psychiatry 2005; 162: 1461-72.
47. Kim S. J., Lyoo I. K., Hwang J., Chung A., Hoon Sung Y., Kim J. etal. Prefrontal grey-matter changes in short-term and long-term abstinent methamphetamine abusers. Int J Neuropsychopharmacol 2006; 9: 221-8.
48. Lawyer G., Bjerkan P. S., Hammarberg A., Jayaram-Lindstrom N., Franck J., Agartz I. Amphetamine dependence and co-morbid alcohol abuse: associations to brain cortical thickness. BMC Pharmacol 2010; 10: 5.
49. Cardenas V. A., Studholme C., Gazdzinski S., Durazzo T. C., Meyerhoff D. J. Deformation-based morphometry of brain changes in alcohol dependence and abstinence. Neuroimage 2007; 34: 879-87.
50. Johnston D. W., Gold A., Kentish J., Smith D., Vallance P., Shah D. etal. Effect of stress management on blood pressure in mild primary hypertension. BMJ 1993; 306: 963-6.
51. Conway K. P., Compton W., Stinson F. S., Grant B. F. Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry 2006; 67: 247-57.
52. Ownby R. L., Crocco E., Acevedo A., John V., Loewenstein D. Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis. Arch Gen Psychiatry 2006; 63: 530-8.