Loss of contraction force in dermal fibroblasts with aging due to decreases in myosin light chain phosphorylation enzymes

Archives of Pharmacal Research

Volumn 34, Issue 6, 2011, Pages 1015-1022

  Fujimura, Tsutomu ^a   Hotta, Mitsuyuki ^a   Kitahara, Takashi ^a   Takema, Yoshinori ^a  

^a KAO CORPORATION   (Japan)

Author keywords

Aging; Contraction force; Fibroblasts; Myosin light chain kinase; Rho kinase

Indexed keywords

COLLAGEN GEL; LYSOPHOSPHATIDIC ACID; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN KINASE 20; MYOSIN LIGHT CHAIN PHOSPHATASE; RHO KINASE; ROCK 1 KINASE; ROCK 2 KINASE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL AGING; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOTION ANALYSIS SYSTEM; MOUSE; NONHUMAN; NONMUSCLE CELL CONTRACTION; PROTEIN DEPLETION; PROTEIN EXPRESSION; SKIN FIBROBLAST;

AGE FACTORS; AGING; ANIMALS; COLLAGEN; FEMALE; FIBROBLASTS; GELS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LYSOPHOSPHOLIPIDS; MICE; MICE, HAIRLESS; MICE, INBRED ICR; MUSCLE CONTRACTION; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; PHOSPHORYLATION; RHO-ASSOCIATED KINASES; THROMBIN; TIME FACTORS;

EID: 79960235199     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0619-9     Document Type: Article

References (37)

1. M. Amano M. Ito K. Kimura Y. Fukata K. Chihara T. Nakano Y. Matsuura K. Kaibuchi 1996 Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase) J. Biol. Chem. 271 20246 20249 8702756 10.1074/jbc.271.34.20246 1:CAS:528:DyaK28Xlt1ygt7Y%3D (Pubitemid 26281788)
2. J. Bao K. Oishi T. Yamada L. Liu A. Nakamura M. K. Uchida K. Kohama 2002 Role of the short isoform of myosin light chain kinase in the contraction of cultured smooth muscle cells as examined by its down-regulation Proc. Natl. Acad. Sci. U. S. A. 99 9556 9561 12087128 10.1073/pnas.142298599 1:CAS:528:DC%2BD38XlsVGgtbw%3D (Pubitemid 34764651)
3. J. Belik E. Kerc M. D. Pato 2006 Rat pulmonary arterial smooth muscle myosin light chain kinase and phosphatase activities decrease with age Am. J. Physiol. Lung Cell. Mol. Physiol. 290 L509 L516 16214816 10.1152/ajplung.00145. 2005 1:CAS:528:DC%2BD28Xjt1Skt7Y%3D (Pubitemid 43738991)
4. E. R. Blough K. M. Rice D. H. Desai P. Wehner G. L. Wright 2007 Aging alters mechanical and contractile properties of the Fisher 344/Nnia X Norway/Binia rat aorta Biogerontology 8 303 313 17164981 10.1007/s10522-006- 9074-2 1:CAS:528:DC%2BD2sXkvVaiu7s%3D (Pubitemid 46711485)
5. H. P. Ehrlich J. B. Rajaratnam 1990 Cell locomotion forces versus cell contraction forces for collagen lattice contraction: an in vitro model of wound contraction Tissue Cell 22 407 417 2260082 10.1016/0040-8166(90)90070-P 1:CAS:528:DyaK3MXhs1Wktbo%3D (Pubitemid 20278640)
6. 3 J. Dermatol. Sci. 24 105 111 11064245 10.1016/S0923-1811(00)00090-6 1:CAS:528:DC%2BD3cXosFSntLw%3D
7. T. Fujimura S. Moriwaki M. Hotta T. Kitahara Y. Takema 2006 Horse chestnut extract induces contraction force generation in fibroblasts through activation of Rho/Rho kinase Biol. Pharm. Bull. 29 1075 1081 16754996 10.1248/bpb.29.1075 1:CAS:528:DC%2BD28XnslOmtL0%3D (Pubitemid 43845463)
8. T. Fujimura S. Moriwaki G. Imokawa Y. Takema 2007 Crucial role of fibroblast integrins alpha2 and beta1 in maintaining the structural and mechanical properties of the skin J. Dermatol. Sci. 45 45 53 17118629 10.1016/j.jdermsci.2006.09.012 1:CAS:528:DC%2BD2sXhsFGmsw%3D%3D (Pubitemid 44969508)
9. L. Germain A. Jean F. A. Auger D. R. Garrel 1994 Human wound healing fibroblasts have greater contractile properties than dermal fibroblasts J. Surg. Res. 57 268 273 8028334 10.1006/jsre.1994.1143 1:STN:280:DyaK2czgtV2lug%3D%3D (Pubitemid 24262399)
10. J. M. Gibson S. B. Milam R. J. Klebe 1989 Late passage cells display an increase in contractile behavior Mech. Ageing Dev. 48 101 110 2739467 10.1016/0047-6374(89)90042-0 1:STN:280:DyaL1M3psVOitA%3D%3D (Pubitemid 19130659)
11. F. Grinnell 1994 Fibroblasts, myofibroblasts, and wound contraction J. Cell Biol. 124 401 404 8106541 10.1083/jcb.124.4.401 1:CAS:528: DyaK2cXhtlSqsLs%3D (Pubitemid 24064453)
12. A. K. Harris D. Stopak P. Wild 1981 Fibroblast traction as a mechanism for collagen morphogenesis Nature 290 249 251 7207616 10.1038/290249a0 1:STN:280:DyaL3M7kvVyntA%3D%3D (Pubitemid 11149655)
13. B. Hinz G. Gabbiani 2003 Mechanisms of force generation and transmission by myofibroblasts Curr. Opin. Biotechnol. 14 538 546 14580586 10.1016/j.copbio.2003.08.006 1:CAS:528:DC%2BD3sXot12hsr0%3D (Pubitemid 37298041)
14. B. Hinz 2007 Formation and function of the myofibroblast during tissue repair J. Invest. Dermatol. 127 526 537 17299435 10.1038/sj.jid.5700613 1:CAS:528:DC%2BD2sXhs1Crt7o%3D
15. K. E. Kamm J. T. Stull 1985 Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle Annu. Rev. Pharmacol. Toxicol. 25 593 620 2988424 10.1146/annurev.pa.25.040185.003113 1:STN:280:DyaL2M3itl2kug%3D%3D
16. K. Kimura M. Ito M. Amano K. Chihara Y. Fukata M. Nakafuku B. Yamamori J. Feng T. Nakano K. Okawa A. Iwamatsu K. Kaibuchi 1996 Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rhokinase) Science 273 245 248 8662509 10.1126/science.273.5272.245 1:CAS:528:DyaK28Xkt1Crs7Y%3D (Pubitemid 26285892)
17. M. S. Kolodney R. B. Wysolmerski 1992 Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study J. Cell Biol. 117 73 82 1556157 10.1083/jcb.117.1.73 1:CAS:528:DyaK38XhvFWktLs%3D
18. T. Kono T. Tanii M. Furukawa N. Mizuno J. Kitajima M. Ishii T. Hamada 1990 Correlation between ageing and collagen gel contractility of human fibroblasts Acta Derm. Venereol. 70 241 244 1972839 1:STN:280: DyaK3c3ps1OrsQ%3D%3D (Pubitemid 20172429)
19. G. Majno G. Gabbiani B. J. Hirschel G. B. Ryan P. R. Statkov 1971 Contraction of granulation tissue in vitro: similarity to smooth muscle Science 173 548 550 4327529 10.1126/science.173.3996.548 1:CAS:528:DyaE3MXltlylsro%3D
20. T. Matsui M. Amano T. Yamamoto K. Chihara M. Nakafuku M. Ito T. Nakano K. Okawa A. Iwamatsu K. Kaibuchi 1996 Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho EMBO J. 15 2208 2216 8641286 1:CAS:528:DyaK28XjtFyjtrY%3D (Pubitemid 26141137)
21. L. Miao J. W. Calvert J. Tang A. D. Parent J. H. Zhang 2001 Age-related RhoA expression in blood vessels of rats Mech. Ageing Dev. 122 1757 1770 11557278 10.1016/S0047-6374(01)00297-4 1:CAS:528:DC%2BD3MXms12lsbs%3D (Pubitemid 32835221)
22. B. K. Pilcher N. S. Levine J. J. Tomasek 1995 Thrombin promotion of isometric contraction in fibroblasts: its extracellular mechanism of action Plast. Reconstr. Surg. 96 1188 1195 7568497 10.1097/00006534-199510000-00029 1:STN:280:DyaK28%2FhvV2qsw%3D%3D
23. A. Poperechnaya O. Varlamova P. J. Lin J. T. Stull A. R. Bresnick 2000 Localization and activity of myosin light chain kinase isoforms during the cell cycle J. Cell Biol. 151 697 708 11062269 10.1083/jcb.151.3.697 1:CAS:528:DC%2BD3cXnsl2lsbs%3D
24. E. Prochniewicz D. D. Thomas L. V. Thompson 2005 Agerelated decline in actomyosin function J. Gerontol. A Biol. Sci. Med. Sci. 60 425 431 15933379 10.1093/gerona/60.4.425
25. E. Prochniewicz L. V. Thompson D. D. Thomas 2007 Agerelated decline in actomyosin structure and function Exp. Gerontol. 42 931 938 17706387 10.1016/j.exger.2007.06.015 1:CAS:528:DC%2BD2sXhtVOitLvJ (Pubitemid 47418560)
26. I. S. Raj S. R. Bird A. J. Shield 2010 Aging and the forcevelocity relationship of muscles Exp. Gerontol. 45 81 90 19883746 10.1016/j.exger.2009. 10.013 1:CAS:528:DC%2BC3cXpslWqug%3D%3D
27. G. M. Rayan J. J. Tomasek 1994 Generation of contractile force by cultured Dupuytren's disease and normal palmar fibroblasts Tissue Cell 26 747 756 9437248 10.1016/0040-8166(94)90057-4 1:STN:280:DyaK1c%2FpvFyqtg%3D%3D (Pubitemid 24298074)
28. A. J. Ridley A. Hall 1992 The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors Cell 70 389 399 1643657 10.1016/0092-8674(92)90163-7 1:CAS:528:DyaK38XlsVyisro%3D
29. A. P. Somlyo A. V. Somlyo 1994 Signal transduction and regulation in smooth muscle Nature 372 231 236 7969467 10.1038/372231a0 1:CAS:528: DyaK2MXit1Oqs7g%3D (Pubitemid 24352442)
30. A. P. Somlyo A. V. Somlyo 2000 Signal transduction by Gproteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II J. Physiol. 522 177 185 10639096 10.1111/j.1469-7793.2000.t01-2-00177.x 1:CAS:528:DC%2BD3cXht12ns7s%3D (Pubitemid 30068498)
31. L. V. Thompson M. Brown 1999 Age-related changes in contractile properties of single skeletal fibers from the soleus muscle J. Appl. Physiol. 86 881 886 10066700 10.1063/1.370818 1:STN:280:DyaK1M7pvFemsA%3D%3D (Pubitemid 29118008)
32. N. Tsuji S. Moriwaki Y. Suzuki Y. Takema G. Imokawa 2001 The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity Photochem. Photobiol. 74 283 290 11547567 10.1562/0031-8655(2001)074<0283:TROESB>2.0.CO;2 1:CAS:528:DC%2BD3MXmsFShsbs%3D
33. C. Viennet J. Bride V. Armbruster F. Aubin A. C. Gabiot T. Gharbi P. Humbert 2005 Contractile forces generated by striae distensae fibroblasts embedded in collagen lattices Arch. Dermatol. Res. 297 10 17 15883849 10.1007/s00403-005-0557-9 (Pubitemid 41380677)
34. I. B. Wall N. Bhadal S. Broad S. A. Whawell V. Mudera M. P. J. Lewis 2009 Force generation and protease gene expression in organotypic co-cultures of fibroblasts and keratinocytes J. Tissue Eng. Regen. Med. 3 647 650 19701934 10.1002/term.206 1:CAS:528:DC%2BC3cXlsVShs74%3D
35. L. K. Wrobel T. R. Fray J. E. Molloy J. J. Adams M. P. Armitage J. C. Sparrow 2002 Contractility of single human dermal myofibroblasts and fibroblasts Cell Motil. Cytoskeleton 52 82 90 12112150 10.1002/cm.10034 (Pubitemid 34568958)
36. M. Yamato K. Yamamoto T. Hayashi 1993 Age-related changes in collagen gel contraction by cultured human lung fibroblasts resulting in cross-over of contraction curves between young and aged cells Mech. Ageing Dev. 67 149 158 8469027 10.1016/0047-6374(93)90119-C 1:CAS:528:DyaK3sXitlWisrc%3D (Pubitemid 223040758)
37. H. F. Jr. Yee A. C. Melton B. N. Tran 2001 RhoA/rho-associated kinase mediates fibroblast contractile force generation Biochem. Biophys. Res. Commun. 280 1340 1345 11162676 10.1006/bbrc.2001.4291 1:CAS:528:DC%2BD3MXptlGjsw%3D%3D (Pubitemid 32917791)