Marjolin ulcer: An overlooked entity

International Wound Journal

Volumn 8, Issue 4, 2011, Pages 419-424

  Pavlovic, Sasha ^a   Wiley, Elizabeth ^a   Guzman, Grace ^a   Morris, David ^a   Braniecki, Marylee ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Biopsy; Chronic non healing ulcer; Marjolin ulcer; Squamous cell carcinoma

Indexed keywords

ANTIBIOTIC AGENT;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; BURN SCAR; CASE REPORT; CELL INFILTRATION; CHRONIC DISEASE; DECUBITUS; FISTULA; GLUTEUS MAXIMUS MUSCLE; HEALTH CARE PERSONNEL; HISTOPATHOLOGIC SKIN REACTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LACERATION; LEPROSY; MALE; MARJOLIN ULCER; PRIORITY JOURNAL; PROGNOSIS; SKIN BIOPSY; SQUAMOUS CELL CARCINOMA; TUMOR DIFFERENTIATION; ULCER; VENOUS STASIS; WOUND HEALING;

BIOPSY; CARCINOMA, SQUAMOUS CELL; DIAGNOSIS, DIFFERENTIAL; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; SKIN NEOPLASMS; SKIN ULCER; WOUNDS AND INJURIES;

EID: 79960227002     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/j.1742-481X.2011.00811.x     Document Type: Article

References (42)

1. Barr LH, Menard JW. Marjolin's ulcer. The LSU experience. Cancer 1983;52:173-5.
2. Esther RJ, Lamps L, Schwartz HS. Marjolin ulcers: secondary carcinomas in chronic wounds. J South Orthop Assoc 1999;8:181-7.
3. Ozek C, Celik N, Bilkay U, Akalin T, Erdem O, Cagdas A. Marjolin's ulcer of the scalp: report of 5 cases and review of the literature. J Burn Care Rehabil 2001;22:65-9.
4. Eltorai IM, Montroy RE, Kobayashi M, Jakowatz J, Guttierez P. Marjolin's ulcer in patients with spinal cord injury. J Spinal Cord Med 2002;25: 191-6.
5. Bauer T, David T, Rimareix F, Lortat-Jacob A. Marjolin's ulcer in chronic osteomyelitis: seven cases and a review of the literature. Rev Chir Orthop Reparatrice Appar Mot 2007;93:63-71.
6. Smith J, Mello LF, Nogueira Neto NC, Meohas W, Pinto LW, Campos VA, Barcellos MG, Fiod NJ, Rezende JF, Cabral CE. Malignancy in chronic ulcers and scars of the leg (Marjolin's ulcer): a study of 21 patients. Skeletal Radiol 2001;30: 331-7.
7. Bauk VOZ, Assuncao AM, Domingues RE. Marjolin's ulcer: a twelve-case report. An Bras Dermatol 2006;81:355-8.
8. Grauwin MY, Mane I, Cartel JL. Pseudoepitheliomatous hyperplasia in trophic ulcers in leprosy patients. A 28-case study. Lepr Rev 1996;67:203-7.
9. Baldursson B, Sigurgeirsson B, Lindelof B. Venous leg ulcers and squamous cell carcinoma: a large-scale epidemiological study. Br J Dermatol 1995;133:571-4.
10. Grenier JM, Barriere I, Rouffy J. Malignant transformation of leg ulcers. Rev Med Interne 1993;14:51-3.
11. Copcu E, Aktas A, Sisman N, Oztan Y. Thirty-one cases of Marjolin's ulcer. Clin Exp Dermatol 2003;28:138-41.
12. Dupree MT, Boyer JD, Cobb MW. Marjolin's ulcer arising in a burn scar. Cutis 1998;62:49-51.
13. Kerr-Valentic MA, Samimi K, Rohlen BH, Agarwal JP, Rockwell WB. Marjolin's ulcer: modern analysis of an ancient problem. Plast Reconstr Surg 2009;123:184-91.
14. Marjolin J, Ulcere. In: Adelon NP, editor. Dictionnaire de medicine. Paris: Bechet, 1828:31-50.
15. Steffen C. The man behind the eponym. Jean-Nicolas Marjolin. Am J Dermatopathol 1984;6: 163-5.
16. Lynch JM. Understanding pseudoepitheliomatous hyperplasia. Pathol Case Rev 2004;9:36-45.
17. Ozyazgan I, Kontacs O. Basal cell carcinoma arising from surgical scars: a case and review of the literature. Dermatol Surg 1999;25:965-8.
18. Drut R, Barletta L. Osteogenic sarcoma arising in an old burn scar. J Cutan Pathol 1975;2:302-6.
19. Lawrence EA. Carcinoma arising in the scars of thermal burns, with special reference to the influence of the age at burn on the length of the induction period. Surg Gynecol Obstet 1952;95: 579-88.
20. Copcu E. Marjolin's ulcer: a preventable complication of burns? Plast Reconstr Surg 2009;124: 156e-64e.
21. Copcu E, Culhaci N. Marjolin's ulcer on the nose. Burns 2002;28:701-4.
22. Pratt DV, Pelton RW, Patel BC, Anderson RL. Burn scar malignancies of the eyelids. Ophthal Plast Reconstr Surg 2000;16:432-7.
23. Wright MW, McCarthy RA, Kelly EB, Wright ST, Wagner RF. Basal cell carcinoma arising in a cleft lip repair scar. Dermatol Surg 2001;27:195-7.
24. Treves NPG. The development of cancer in burn scars. Surg Gynecol Obstet 1930;51:749-82.
25. Hill BB, Sloan DA, Lee EY, McGrath PC, Kenady DE. Marjolin's ulcer of the foot caused by nonburn trauma. South Med J 1996;89:707-10.
26. Fleming MD, Hunt JL, Purdue GF, Sandstad J. Marjolin's ulcer: a review and reevaluation of a difficult problem. J Burn Care Rehabil 1990;11:460-9.
27. Hahn SB, Kim DJ, Jeon CH. Clinical study of Marjolin's ulcer. Yonsei Med J 1990;31:234-41.
28. Enoch S, Miller DR, Price PE, Harding KG. Early diagnosis is vital in the management of squamous cell carcinomas associated with chronic non healing ulcers: a case series and review of the literature. Int Wound J 2004;1:165-75.
29. Cavadas PC, Baena-Montilla P, Jorda-Cuevas J, Vera-Sempere FJ. Primary intracranial malignant tumour mistaken for a postburn scalp Marjolin's ulcer. Burns 1996;22:331-4.
30. Rapini R. Practical dermatopathology, 1st edn. Philadelphia: Elsevier Mosby, 2005.
31. Weedon D. Skin pathology, 2nd edn. Sydney: Churchill Livingstone, 2002.
32. Bernard KGYA, Lucas J. The new Aird's companion in surgical studies, 2nd edn. London: Churchill Livingstone, 2005.
33. Copcu E, Sivrioglu N, Baytekin C, Koc B, Er S. Very acute and aggressive form of Marjolin's ulcer caused by single blunt trauma to the burned area. J Burn Care Rehabil 2005;26:459-60.
34. Moller R, Reymann F, Hou-Jensen K. Metastases in dermatological patients with squamous cell carcinoma. Arch Dermatol 1979;115:703-5.
35. Sabin SR, Goldstein G, Rosenthal HG, Haynes KK. Aggressive squamous cell carcinoma originating as a Marjolin's ulcer. Dermatol Surg 2004;30(2 Suppl Pt 1): 229-30.
36. Eastman AL, Erdman WA, Lindberg GM, Hunt JL, Purdue GF, Fleming JB. Sentinel lymph node biopsy identifies occult nodal metastases in patients with Marjolin's ulcer. J Burn Care Rehabil 2004;25:241-5.
37. Ames FC, Hickey RC. Metastasis from squamous cell skin cancer of the extremities. South Med J 1982;75:920-3.
38. Ryan RF, Litwin MS, Krementz ET. A new concept in the management of Marjolin's ulcers. Ann Surg 1981;193:598-605.
39. Bean DJ, Rees RS, O'Leary JP, Lynch JB. Carcinoma of the hand: a 20-year experience. South Med J 1984;77:998-1000.
40. Ames FC, Hickey RC. Squamous cell carcinoma of the skin of the extremities. Int Adv Surg Oncol 1980;3:179-99.
41. Ozek C, Cankayali R, Bilkay U, Guner U, Gundogan H, Songur E, Akin Y, Cagdas A. Marjolin's ulcers arising in burn scars. J Burn Care Rehabil 2001;22:384-9.
42. Asuquo M, Ugare G, Ebughe G, Jibril P. Marjolin's ulcer: the importance of surgical management of chronic cutaneous ulcers. Int J Dermatol 2007;46 (2 Suppl): 29-32.