The lockingmousenail - A new implant for standardized stable osteosynthesis in mice

Journal of Surgical Research

Volumn 169, Issue 2, 2011, Pages 220-226

  Garcia, Patric ^a   Herwerth, Simon ^a   Matthys, Romano ^b   Holstein, Joerg H ^a   Histing, Tina ^a   Menger, Michael D ^a   Pohlemann, Tim ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b AO Development Institute   (Switzerland)

Author keywords

biomechanics; bone; bone healing; bone regeneration; fracture fixation; fracture healing; mice; osteosynthesis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; CALLUS; FEMUR FRACTURE; FRACTURE HEALING; IMPLANT; INTERLOCKING NAIL; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOSYNTHESIS; OSTEOTOMY; PRIORITY JOURNAL;

ANIMALS; BIOMECHANICS; BONE NAILS; BONE REGENERATION; FEMORAL FRACTURES; FRACTURE FIXATION, INTERNAL; FRACTURE FIXATION, INTRAMEDULLARY; FRACTURE HEALING; MICE; MODELS, ANIMAL; OSTEOTOMY; PROSTHESES AND IMPLANTS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 79960226315     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.11.713     Document Type: Article

References (25)

1. M.B. Manigrasso, and J.P. O'Connor Characterization of a closed femur fracture model in mice J Orthop Trauma 18 2004 687
2. P. Garcia, J.H. Holstein, and T. Histing A new technique for internal fixation of femoral fractures in mice: Impact of stability on fracture healing J Biomech 41 2008 1689
3. J.H. Holstein, R. Matthys, and T. Histing Development of a stable closed femoral fracture model in mice J Surg Res 153 2009 71
4. J.H. Holstein, M.D. Menger, and U. Culemann Development of a locking femur nail for mice J Biomech 40 2007 215
5. T. Histing, J.H. Holstein, and P. Garcia Ex vivo analysis of rotational stiffness of different osteosynthesis techniques in mouse femur fracture J Orthop Res 27 2009 1152
6. P. Garcia, J.H. Holstein, and S. Maier Development of a reliable non-union model in mice J Surg Res 147 2008 84
7. L. Claes, P. Augat, and G. Suger Influence of size and stability of the osteotomy gap on the success of fracture healing J Orthop Res 15 1997 577
8. E.Y. Chao, and N. Inoue Biophysical stimulation of bone fracture repair, regeneration, and remodeling Eur Cell Mater 6 2003 72
9. K.M. Cheung, K. Kaluarachi, and G. Andrew An externally fixed femoral fracture model for mice J Orthop Res 21 2003 685
10. Z. Thompson, T. Miclau, and D. Hu A model for intramembranous ossification during fracture healing J Orthop Res 20 2002 1091
11. J.H. Holstein, M. Klein, and P. Garcia Rapamycin affects early fracture healing in mice Br J Pharmacol 154 2008 1055
12. J.H. Holstein, M.D. Menger, and C. Scheuer Erythropoietin (EPO): EPO-receptor signaling improves early endochondral ossification and mechanical strength in fracture healing Life Sci 80 2007 893
13. M. Bhandari, and E.H. Schemitsch Bone formation following intramedullary femoral reaming is decreased by indomethacin and antibodies to insulin-like growth factors J Orthop Trauma 16 2002 717
14. F.H. Shen, J.M. Visger, and G. Balian Systemically administered mesenchymal stromal cells transduced with insulin-like growth factor-I localize to a fracture site and potentiate healing J Orthop Trauma 16 2002 651
15. A.M. Simon, M.B. Manigrasso, and J.P. O'Connor Cyclo-oxygenase 2 function is essential for bone fracture healing J Bone Miner Res 17 2002 963
16. C. Colnot, Z. Thompson, and T. Miclau Altered fracture repair in the absence of MMP9 Development 130 2003 4123
17. A.X. Le, T. Miclau, and D. Hu Molecular aspects of healing in stabilized and non-stabilized fractures J Orthop Res 19 2001 78
18. A. Opolka, S. Ratzinger, and T. Schubert Collagen IX is indispensable for timely maturation of cartilage during fracture repair in mice Matrix Biol 26 2007 85
19. J.H. Holstein, R. Matthys, and T. Histing Development of a Stable Closed Femoral Fracture Model in Mice J Surg Res 153 2008 71
20. C.K. Connolly, G. Li, J.R. Bunn, and M. Mushipe A reliable externally fixated murine femoral fracture model that accounts for variation in movement between animals J Orthop Res 21 2003 843
21. I. Grongroft, P. Heil, and R. Matthys Fixation compliance in a mouse osteotomy model induces two different processes of bone healing but does not lead to delayed union J Biomech 42 2009 2089
22. Histing T, Garcia P, and Matthys R An internal locking plate to study intramembranous bone healing in a mouse femur fracture model J Orthop Res 2009
23. E.A. Smith-Adaline, S.K. Volkman, and M.A. Ignelzi Jr Mechanical environment alters tissue formation patterns during fracture repair J Orthop Res 22 2004 1079
24. D.M. Nunamaker Experimental models of fracture repair Clin Orthop Relat Res 1998 S56
25. J.W. Thomas, J.W. Touchman, and R.W. Blakesley Comparative analyses of multi-species sequences from targeted genomic regions Nature 424 2003 788