Redesigning a large school-based clinical trial in response to changes in community practice

Clinical Trials

Volumn 8, Issue 3, 2011, Pages 311-319

  Gerald, Lynn B ^a   Gerald, Joe K ^a   McClure, Leslie A ^b   Harrington, Kathy ^b   Erwin, Sue ^b   Bailey, William C ^b  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL;

ARTICLE; ASTHMA; CHILD; CLINICAL TRIAL (TOPIC); COMMUNITY CARE; CONTROLLED STUDY; CROSSOVER PROCEDURE; HAND WASHING; HUMAN; MAJOR CLINICAL STUDY; PATIENT SAFETY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SCHOOL HEALTH SERVICE;

ALABAMA; CHILD; CROSS-OVER STUDIES; HANDWASHING; HUMANS; INTERVIEWS AS TOPIC; LONGITUDINAL STUDIES; RESEARCH DESIGN; RESPIRATORY TRACT INFECTIONS; SCHOOLS; STATUS ASTHMATICUS;

EID: 79960224156     PISSN: 17407745     EISSN: 17407753     Source Type: Journal    
DOI: 10.1177/1740774511403513     Document Type: Article

References (44)

1. Akinbami LJ, Schoendorf KC. Trends in childhood asthma: prevalence, health care utilization, and mortality. Pediatrics. 2002 ; 110: 315-22 (Pubitemid 34833016)
2. Akinbami L. The state of childhood asthma, United States, 1980-2005. Adv Data. 2006 ; 381: 1-24
3. Schmier JK, Manjunath R, Halpern MT, et al. The impact of inadequately controlled asthma in urban children on quality of life and productivity. Ann Allergy Asthma Immunol. 2007 ; 98: 245-51 (Pubitemid 46420233)
4. Bateman ED, Frith LF, Braunstein GL. Achieving guideline-based asthma control: does the patient benefit?. Eur Respir J. 2002 ; 20: 588-95
5. Dales RE, Schweitzer I, Toogood JH, et al. Respiratory infections and the autumn increase in asthma morbidity. Eur Respir J. 1996 ; 9: 72-77 (Pubitemid 26037529)
6. Silverman RA, Ito K, Stevenson L, Hastings HM. The relationship of fall school opening and emergency department asthma visits in a large metropolitan area. Arch Pediatr Adolesc Med. 2005 ; 159: 818-23 (Pubitemid 41248388)
7. Blaisdell CJ, Weiss SR, Kimes DS, et al. Using seasonal variations in asthma hospitalizations in children to predict hospitalization frequency. J Asthma. 2002 ; 39: 567-75
8. Johnston NW, Johnston SL, Ducan JM, et al. The September epidemic of asthma exacerbations in children: a search for etiology. J Allergy Clin Immunol. 2005 ; 115: 132-38 (Pubitemid 40075433)
9. Freymuth F, Vabret A, Brouard J, et al. Detection of viral, Chlamydia pneumoniae and Mycoplasma pneumoniae infections in exacerbations of asthma in children. J Clin Virol. 1999 ; 13: 131-39 (Pubitemid 29349101)
10. Johnston SL, Pattemore PK, Sanderson G, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ. 1995 ; 310: 1225-29
11. Monto AS. The seasonality of rhinovirus infections and its implications for clinical recognition. Clin Ther. 2002 ; 24: 1987-97 (Pubitemid 36051527)
12. Rakes GP, Arruda E, Ingram JM, et al. Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses. Am J Respir Crit Care Med. 1999 ; 159: 785-90 (Pubitemid 29137774)
13. Thumerelle C, Deschildre A, Bouquillon C, et al. Role of viruses and atypical bacteria in exacerbations of asthma in hospitalized children: a prospective study in the Nord-Pas de Calais region (France). Pediatr Pulmonol. 2003 ; 35: 75-82 (Pubitemid 36177099)
14. Guideline for hand hygiene in health-care settings: recommendations of the healthcare infection control practices advisory committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. MMWR. 2002 ; 51: 1-44
15. Jefferson T, Del Mar C, Dooley L, et al. Physical interventions to interrupt or reduce the spread of respiratory viruses: systematic review. BMJ. 2009 ; 339: b3675 - b3675
16. Lee GM, Salomon JA, Friedman JF, et al. Illness transmission in the home: a possible role for alcohol-based hand gels. Pediatrics. 2005 ; 115: 852-60
17. White CG, Shinder FS, Shinder AL, Dyer DL. Reduction of illness absenteeism in elementary schools using an alcohol-free instant hand sanitizer. J Sch Nurs. 2001 ; 17: 258-65
18. Guinan M, McGuckin M, Ali Y. The effect of a comprehensive handwashing program on absenteeism in elementary schools. Am J Infect Control. 2002 ; 30: 217-20 (Pubitemid 34596923)
19. Robinson J. The changing role of the school nurse: a partner in infection control and disease prevention. J Sch Nurs. 2002 ; Suppl.: 12-14
20. Vessey JA, Sherwood JJ, Warner D, Clark D. Comparing hand washing to hand sanitizers in reducing elementary school students' absenteeism. Pediatr Nurs. 2007 ; 33: 368-72
21. Early E, Battle K, Cantwall E, et al. Effect of several interventions on the frequency of handwashing among elementary public school children. Am J Infect Control. 1998 ; 26: 263-69 (Pubitemid 28287466)
22. Ramos MM, Blea M, Trujillo R, Greenberg C. Inspections of hand washing supplies and hand sanitizer in public schools. J Sch Nurs. 2010 ; 26: 393-97
23. White C, Kolble R, Carlson R, et al. The effect of hand hygiene on illness rate among students in university residence halls. Am J Infect Control. 2003 ; 31: 364-70 (Pubitemid 37222814)
24. Morton JL, Schulta AA. Healthy hands: use of alcohol gel as an adjunct to handwashing in elementary school children. J Sch Nurs. 2004 ; 20: 161-67
25. Hammond B, Ali Y, Fendler E, et al. Effect of hand sanitizer use on elementary school absenteeism. Am J Infect Control. 2000 ; 28: 340-46
26. Dyer DL, Shinder A, Shinder F. Alcohol-free instant hand sanitizer reduces elementary school illness absenteeism. Fam Med. 2000 ; 32: 633-38
27. Sandora TJ, Taveras EM, Shih MC, et al. A randomized, controlled trial of a multifaceted intervention including alcohol-based hand sanitizer and hand-hygiene education to reduce illness transmission in the home. Pediatrics. 2005 ; 116: 587-94 (Pubitemid 44336671)
28. Meadows E, LeSaux N. A systematic review of the effectiveness of antimicrobial rinse-free hand sanitizers for prevention of illness-related absenteeism in elementary school children. BMC Public Health. 2004 ; 4: 50-50
29. Gerald LB, McClure LA, Mangan JM, et al. Increasing adherence to inhaled steroid therapy among schoolchildren: randomized, controlled trial of school-based supervised asthma therapy. Pediatrics. 2009 ; 123: 466-74
30. Centers for Disease Control and Prevention. Clean Hands Saves Lives!; 2010, http://www.cdc.gov/handwashing/ (accessed 22 March 2011).
31. Tentative final monograph for health-care antiseptic drug products: proposed rule. Fed Regist. 1994 ; 59: 31441-52
32. Wood A, Payne D. The action of three antiseptics/disinfectants against enveloped and non-enveloped viruses. J Hosp Infect. 1998 ; 38: 283-95 (Pubitemid 28187949)
33. Dyer DL, Gerenraich KB, Wadhams PS. Testing a new alcohol-free hand sanitizer to combat infection. AORN J. 1998 ; 68: 239-241
34. Moadab A, Rupley KF, Wadhams P. Effectiveness of a nonrinse, alcohol-free antiseptic hand wash. J Am Podiatr Med Assoc. 2001 ; 91: 288-93
35. Bryant KA, Pearce J, Stover B. Flash fire associated with the use of alcohol-based antiseptic agent. Am J Infect Control. 2002 ; 30: 256-57 (Pubitemid 34596932)
36. Roberts HS, Self RJ, Coxon M. An unusual complication of hand hygiene. Anaesthesia. 2005 ; 60: 100-101
37. Ferk F, Misik M, Hoelzl C, et al. Benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB), two common quaternary ammonium compounds, cause genotoxic effects in mammalian and plant cells at environmentally relevant concentrations. Mutagenesis. 2007 ; 22: 363-70 (Pubitemid 350098491)
38. Varani J, Perone P, Spahlinger DM, et al. Human skin in organ culture and human skin cells (keratinocytes and fibroblasts) in monolayer culture for assessment of chemically induced skin damage. Toxicol Pathol. 2007 ; 35: 693-701
39. Houari A, Di Martino P. Effect of chlorhexidine and benzalkonium chloride on bacterial biofilm formation. Lett Appl Microbiol. 2007 ; 45: 652-56 (Pubitemid 350150789)
40. Hann S, Hughes TM, Stone NM. Flexural allergic contact dermatitis to benzalkonium chloride in antiseptic bath oil. Br J Dermatol. 2007 ; 157: 795-98 (Pubitemid 47389910)
41. Marlatt GA, Gordon JR Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors. New York: Guilford Press ; 1985 :
42. Naikoba S, Hayward A. The effectiveness of interventions aimed at increasing handwashing in healthcare workers-a systematic review. J Hosp Infect. 2001 ; 47: 173-80 (Pubitemid 32631844)
43. Flay BR. Efficacy and effectiveness trials (and other phases of research) in the development of health promotion programs. Prev Med.. 1986 ; 14: 451-74
44. Israel BA, Schultz AJ, Parker EA, Becker AB. Review of community-based research: assessing partnership approaches to improve public health. Ann Rev Pub Health. 1998 ; 19: 173-202 (Pubitemid 28279929)