메뉴 건너뛰기




Volumn 17, Issue 8, 2011, Pages 1814-1821

Role of growth factors in the development of lymphangiogenesis driven by inflammatory bowel disease: A review

Author keywords

Crohn's disease; growth factors; inflammatory bowel disease; lymphangiogenesis; lymphangiogenic factors; ulcerative colitis

Indexed keywords

ADIPOCYTOKINE; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; FIBROBLAST GROWTH FACTOR; NITRIC OXIDE SYNTHASE; PLATELET DERIVED GROWTH FACTOR; PODOPLANIN; SCATTER FACTOR; VASCULOTROPIN A; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 3;

EID: 79960222244     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21554     Document Type: Review
Times cited : (30)

References (76)
  • 2
    • 33749016804 scopus 로고    scopus 로고
    • The intestinal microvasculature as a therapeutic target in inflammatory bowel disease
    • DOI 10.1196/annals.1326.003, Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways
    • Hatoum OA, Heidemann J, Binion DG., The intestinal microvasculature as a therapeutic target in inflammatory bowel disease. Ann N Y Acad Sci. 2006; 1072: 78-97. (Pubitemid 44448445)
    • (2006) Annals of the New York Academy of Sciences , vol.1072 , pp. 78-97
    • Hatoum, O.A.1    Heidemann, J.2    Binion, D.G.3
  • 3
    • 33748642793 scopus 로고    scopus 로고
    • El desarrollo vascular en la enfermedad inflamatoria intestinal
    • DOI 10.1157/13091466
    • Pousa ID, Gisbert JP, Mate J,. [Vascular development in inflammatory bowel disease.] Gastroenterol Hepatol. 2006; 29: 414-421. (Pubitemid 44386357)
    • (2006) Gastroenterologia y Hepatologia , vol.29 , Issue.7 , pp. 414-421
    • Pousa, I.D.1    Gisbert, J.P.2    Mate, J.3
  • 5
    • 0035072493 scopus 로고    scopus 로고
    • VEGF, basic-FGF, and TGF-β in Crohn's disease and ulcerative colitis: A novel mechanism of chronic intestinal inflammation
    • DOI 10.1016/S0002-9270(00)02320-0, PII S0002927000023200
    • Kanazawa S, Tsunoda T, Onuma E, et al. VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: a novel mechanism of chronic intestinal inflammation. Am J Gastroenterol. 2001; 96: 822-828. (Pubitemid 32240738)
    • (2001) American Journal of Gastroenterology , vol.96 , Issue.3 , pp. 822-828
    • Kanazawa, S.1    Tsunoda, T.2    Onuma, E.3    Majima, T.4    Kagiyama, M.5    Kikuchi, K.6
  • 6
    • 53549115341 scopus 로고    scopus 로고
    • Identification of lymphatics within the colonic lamina propria in inflammation and neoplasia using the monoclonal antibody D2-40
    • Kenney BC, Jain D., Identification of lymphatics within the colonic lamina propria in inflammation and neoplasia using the monoclonal antibody D2-40. Yale J Biol Med. 2008; 81: 103-113.
    • (2008) Yale J Biol Med , vol.81 , pp. 103-113
    • Kenney, B.C.1    Jain, D.2
  • 7
    • 0042344979 scopus 로고    scopus 로고
    • Lymphatic vessels in the colonic mucosa in ulcerative colitis
    • Kaiserling E, Krober S, Geleff S., Lymphatic vessels in the colonic mucosa in ulcerative colitis. Lymphology. 2003; 36: 52-61. (Pubitemid 36900181)
    • (2003) Lymphology , vol.36 , Issue.2 , pp. 52-61
    • Kaiserling, E.1    Krober, S.2    Geleff, S.3
  • 8
    • 0037331713 scopus 로고    scopus 로고
    • Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells
    • Hirakawa S, Hong YK, Harvey N, et al. Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol. 2003; 162: 575-586. (Pubitemid 36267864)
    • (2003) American Journal of Pathology , vol.162 , Issue.2 , pp. 575-586
    • Hirakawa, S.1    Hong, Y.-K.2    Harvey, N.3    Schacht, V.4    Matsuda, K.5    Libermann, T.6    Detmar, M.7
  • 9
    • 33748771724 scopus 로고    scopus 로고
    • New insights into the molecular control of the lymphatic vascular system and its role in disease
    • DOI 10.1038/sj.jid.5700464, PII 5700464
    • Cueni LN, Detmar M., New insights into the molecular control of the lymphatic vascular system and its role in disease. J Invest Dermatol. 2006; 126: 2167-2177. (Pubitemid 44413162)
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.10 , pp. 2167-2177
    • Cueni, L.N.1    Detmar, M.2
  • 10
    • 14644406264 scopus 로고    scopus 로고
    • Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors
    • Schacht V, Dadras SS, Johnson LA, et al. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005; 166: 913-921. (Pubitemid 40315647)
    • (2005) American Journal of Pathology , vol.166 , Issue.3 , pp. 913-921
    • Schacht, V.1    Dadras, S.S.2    Johnson, L.A.3    Jackson, D.G.4    Hong, Y.-K.5    Detmar, M.6
  • 11
    • 0344407018 scopus 로고    scopus 로고
    • Increase in podoplanin-expressing intestinal lymphatic vessels in inflammatory bowel disease
    • Geleff S, Schoppmann SF, Oberhuber G., Increase in podoplanin-expressing intestinal lymphatic vessels in inflammatory bowel disease. Virchows Arch. 2003; 442: 231-237. (Pubitemid 36399216)
    • (2003) Virchows Archiv , vol.442 , Issue.3 , pp. 231-237
    • Geleff, S.1    Schoppmann, S.F.2    Oberhuber, G.3
  • 12
    • 1442305271 scopus 로고    scopus 로고
    • Proliferation of D2-40-expressing intestinal lymphatic vessels in the lamina propria in inflammatory bowel disease
    • Fogt F, Pascha TL, Zhang PJ, et al. Proliferation of D2-40-expressing intestinal lymphatic vessels in the lamina propria in inflammatory bowel disease. Int J Mol Med. 2004; 13: 211-214.
    • (2004) Int J Mol Med , vol.13 , pp. 211-214
    • Fogt, F.1    Pascha, T.L.2    Zhang, P.J.3
  • 13
    • 37549014137 scopus 로고    scopus 로고
    • Lymphangiogenesis in Crohn's disease: An immunohistochemical study using monoclonal antibody D2-40
    • Pedica F, Ligorio C, Tonelli P, et al. Lymphangiogenesis in Crohn's disease: an immunohistochemical study using monoclonal antibody D2-40. Virchows Arch. 2008; 452: 57-63.
    • (2008) Virchows Arch , vol.452 , pp. 57-63
    • Pedica, F.1    Ligorio, C.2    Tonelli, P.3
  • 14
    • 0028938746 scopus 로고
    • Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
    • Kaipainen A, Korhonen J, Mustonen T, et al. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci U S A. 1995; 92: 3566-3570.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3566-3570
    • Kaipainen, A.1    Korhonen, J.2    Mustonen, T.3
  • 16
    • 0033814892 scopus 로고    scopus 로고
    • VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
    • Partanen TA, Arola J, Saaristo A, et al. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J. 2000; 14: 2087-2096.
    • (2000) FASEB J , vol.14 , pp. 2087-2096
    • Partanen, T.A.1    Arola, J.2    Saaristo, A.3
  • 17
    • 0033451902 scopus 로고    scopus 로고
    • Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors
    • DOI 10.1002/(SICI)1097-0142(19991201)86:11<2406::AID-CNCR31>3.0. CO;2-E
    • Partanen TA, Alitalo K, Miettinen M., Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors. Cancer. 1999; 86: 2406-2412. (Pubitemid 30010384)
    • (1999) Cancer , vol.86 , Issue.11 , pp. 2406-2412
    • Partanen, T.A.1    Alitalo, K.2    Miettinen, M.3
  • 19
    • 77955512358 scopus 로고    scopus 로고
    • Lymphangiogenesis and lymphatic metastasis in breast cancer
    • Ran S, Volk L, Hall K, et al. Lymphangiogenesis and lymphatic metastasis in breast cancer. Pathophysiology. 2010; 17: 229-251.
    • (2010) Pathophysiology , vol.17 , pp. 229-251
    • Ran, S.1    Volk, L.2    Hall, K.3
  • 20
    • 77958536555 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-D in association with VEGF receptor-3 in lymphatic metastasis of breast cancer
    • Chen YN, Gu Y., Vascular endothelial growth factor (VEGF)-D in association with VEGF receptor-3 in lymphatic metastasis of breast cancer. Chin J Cancer. 2009; 28: 1337-1343.
    • (2009) Chin J Cancer , vol.28 , pp. 1337-1343
    • Chen, Y.N.1    Gu, Y.2
  • 21
    • 75649083174 scopus 로고    scopus 로고
    • Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1
    • Flister MJ, Wilber A, Hall KL, et al. Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1. Blood. 2010; 115: 418-429.
    • (2010) Blood , vol.115 , pp. 418-429
    • Flister, M.J.1    Wilber, A.2    Hall, K.L.3
  • 22
    • 33751095944 scopus 로고    scopus 로고
    • Angiogenesis and lymphangiogenesis in thyroid proliferative lesions: Relationship to type and tumour behaviour
    • DOI 10.1677/erc.1.01210
    • de la Torre NG, Buley I, Wass JA, et al. Angiogenesis and lymphangiogenesis in thyroid proliferative lesions: relationship to type and tumour behaviour. Endocr Relat Cancer. 2006; 13: 931-944. (Pubitemid 44763268)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.3 , pp. 931-944
    • Garcia De La Torre, N.1    Buley, I.2    Wass, J.A.H.3    Turner, H.E.4
  • 23
    • 70349096629 scopus 로고    scopus 로고
    • Experimental study of the hepatocyte growth factor contributing to lymphangiogenesis and lymphatic metastasis in gastric cancer
    • Zhang QH, Qian K, Li XJ, et al. [Experimental study of the hepatocyte growth factor contributing to lymphangiogenesis and lymphatic metastasis in gastric cancer]. Zhonghua Wei Chang Wai Ke Za Zhi. 2007; 10: 212-216.
    • (2007) Zhonghua Wei Chang Wai Ke Za Zhi , vol.10 , pp. 212-216
    • Zhang, Q.H.1    Qian, K.2    Li, X.J.3
  • 24
    • 57149104377 scopus 로고    scopus 로고
    • Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues
    • Lohela M, Helotera H, Haiko P, et al. Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues. Am J Pathol. 2008; 173: 1891-1901.
    • (2008) Am J Pathol , vol.173 , pp. 1891-1901
    • Lohela, M.1    Helotera, H.2    Haiko, P.3
  • 25
    • 70350439869 scopus 로고    scopus 로고
    • VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B
    • Onimaru M, Yonemitsu Y, Fujii T, et al. VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B. Am J Physiol Heart Circ Physiol. 2009; 297: H1685-1696.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Onimaru, M.1    Yonemitsu, Y.2    Fujii, T.3
  • 26
    • 66149142809 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis
    • Lahdenranta J, Hagendoorn J, Padera TP, et al. Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis. Cancer Res. 2009; 69: 2801-2808.
    • (2009) Cancer Res , vol.69 , pp. 2801-2808
    • Lahdenranta, J.1    Hagendoorn, J.2    Padera, T.P.3
  • 27
  • 28
    • 69449095482 scopus 로고    scopus 로고
    • Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis
    • Guo R, Zhou Q, Proulx ST, et al. Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis Rheum. 2009; 60: 2666-2676.
    • (2009) Arthritis Rheum , vol.60 , pp. 2666-2676
    • Guo, R.1    Zhou, Q.2    Proulx, S.T.3
  • 29
    • 0033072530 scopus 로고    scopus 로고
    • Growth factors in inflammatory bowel disease
    • Beck PL, Podolsky DK., Growth factors in inflammatory bowel disease. Inflamm Bowel Dis. 1999; 5: 44-60.
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 44-60
    • Beck, P.L.1    Podolsky, D.K.2
  • 30
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM, et al. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science. 1983; 219: 983-985.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3
  • 31
    • 1642326689 scopus 로고    scopus 로고
    • Comparative Evaluation of FGF-2-, VEGF-A-, and VEGF-C-Induced Angiogenesis Lymphangiogenesis, Vascular Fenestrations, and Permeability
    • DOI 10.1161/01.RES.0000118600.91698.BB
    • Cao R, Eriksson A, Kubo H, et al. Comparative evaluation of FGF-2-, VEGF-A-, and VEGF-C-induced angiogenesis, lymphangiogenesis, vascular fenestrations, and permeability. Circ Res. 2004; 94: 664-670. (Pubitemid 38387750)
    • (2004) Circulation Research , vol.94 , Issue.5 , pp. 664-670
    • Cao, R.1    Eriksson, A.2    Kubo, H.3    Alitalo, K.4    Cao, Y.5    Thyberg, J.6
  • 35
    • 78049523086 scopus 로고    scopus 로고
    • VEGF-A/HGF induce Prox-1 expression in the chick embryo chorioallantoic membrane lymphatic vasculature
    • Cimpean AM, Seclaman E, Ceausu R, et al. VEGF-A/HGF induce Prox-1 expression in the chick embryo chorioallantoic membrane lymphatic vasculature. Clin Exp Med. 2010; 10: 169-172.
    • (2010) Clin Exp Med , vol.10 , pp. 169-172
    • Cimpean, A.M.1    Seclaman, E.2    Ceausu, R.3
  • 36
    • 33645815916 scopus 로고    scopus 로고
    • VEGF-A stimulation of leukocyte adhesion to colonic microvascular endothelium: Implications for inflammatory bowel disease
    • Goebel S, Huang M, Davis WC, et al. VEGF-A stimulation of leukocyte adhesion to colonic microvascular endothelium: implications for inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol. 2006; 290: G648-654.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Goebel, S.1    Huang, M.2    Davis, W.C.3
  • 37
    • 0031837973 scopus 로고    scopus 로고
    • Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease
    • DOI 10.1080/00365529850172070
    • Griga T, Tromm A, Spranger J, et al. Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease. Scand J Gastroenterol. 1998; 33: 504-508. (Pubitemid 28277250)
    • (1998) Scandinavian Journal of Gastroenterology , vol.33 , Issue.5 , pp. 504-508
    • Griga, T.1    Tromm, A.2    Spranger, J.3    May, B.4
  • 38
    • 34247499926 scopus 로고    scopus 로고
    • Angiogenesis and inflammatory bowel disease
    • Azzam N., Angiogenesis and inflammatory bowel disease. Saudi J Gastroenterol. 2007; 13: 37-38.
    • (2007) Saudi J Gastroenterol , vol.13 , pp. 37-38
    • Azzam, N.1
  • 39
    • 36048966935 scopus 로고    scopus 로고
    • Analysis of soluble angiogenic factors in Crohn's disease: A preliminary study
    • Duenas Pousa I, Mate Jimenez J, Salcedo Mora X, et al. Analysis of soluble angiogenic factors in Crohn's disease: a preliminary study. Gastroenterol Hepatol. 2007; 30: 518-524.
    • (2007) Gastroenterol Hepatol , vol.30 , pp. 518-524
    • Duenas Pousa, I.1    Mate Jimenez, J.2    Salcedo Mora, X.3
  • 40
    • 58649111743 scopus 로고    scopus 로고
    • VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis
    • Scaldaferri F, Vetrano S, Sans M, et al. VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis. Gastroenterology. 2009; 136: 585 -595 e585.
    • (2009) Gastroenterology , vol.136 , Issue.585-595
    • Scaldaferri, F.1    Vetrano, S.2    Sans, M.3
  • 42
    • 4444255941 scopus 로고    scopus 로고
    • Soluble selectins, sICAM, sVCAM, and angiogenic proteins in different activity groups of patients with inflammatory bowel disease
    • DOI 10.1023/B:DDAS.0000037822.55717.31
    • Magro F, Araujo F, Pereira P, et al. Soluble selectins, sICAM, sVCAM, and angiogenic proteins in different activity groups of patients with inflammatory bowel disease. Dig Dis Sci. 2004; 49: 1265-1274. (Pubitemid 39178099)
    • (2004) Digestive Diseases and Sciences , vol.49 , Issue.7-8 , pp. 1265-1274
    • Magro, F.1    Araujo, F.2    Pereira, P.3    Meireles, E.4    Diniz-Ribeiro, M.5    Velosom, F.T.6
  • 43
    • 0032954072 scopus 로고    scopus 로고
    • Increased production of vascular endothelial growth factor by peripheral blood mononuclear cells in patients with inflammatory bowel disease
    • Griga T, Gutzeit A, Sommerkamp C, et al. Increased production of vascular endothelial growth factor by peripheral blood mononuclear cells in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 1999; 11: 175-179. (Pubitemid 29103579)
    • (1999) European Journal of Gastroenterology and Hepatology , vol.11 , Issue.2 , pp. 175-179
    • Griga, T.1    Gutzeit, A.2    Sommerkamp, C.3    May, B.4
  • 44
    • 0033033616 scopus 로고    scopus 로고
    • + monocytes
    • DOI 10.1023/A:1026640610621
    • Griga T, Werner S, Koller M, et al. Vascular endothelial growth factor (VEGF) in Crohn's disease: increased production by peripheral blood mononuclear cells and decreased VEGF165 labeling of peripheral CD14+ monocytes. Dig Dis Sci. 1999; 44: 1196-1201. (Pubitemid 29297228)
    • (1999) Digestive Diseases and Sciences , vol.44 , Issue.6 , pp. 1196-1201
    • Griga, T.1    Werner, S.2    Koller, M.3    Tromm, A.4    May, B.5
  • 45
    • 0032928383 scopus 로고    scopus 로고
    • Increased production of vascular endothelial growth factor by intestinal mucosa of patients with inflammatory bowel disease
    • Griga T, Voigt E, Gretzer B, et al. Increased production of vascular endothelial growth factor by intestinal mucosa of patients with inflammatory bowel disease. Hepatogastroenterology. 1999; 46: 920-923. (Pubitemid 29224765)
    • (1999) Hepato-Gastroenterology , vol.46 , Issue.26 , pp. 920-923
    • Griga, T.1    Voigt, E.2    Gretzer, B.3    Brasch, F.4    May, B.5
  • 46
    • 0036216571 scopus 로고    scopus 로고
    • Immunohistochemical localization of vascular endothelial growth factor in colonic mucosa of patients with inflammatory bowel disease
    • Griga T, May B, Pfisterer O, et al. Immunohistochemical localization of vascular endothelial growth factor in colonic mucosa of patients with inflammatory bowel disease. Hepatogastroenterology. 2002; 49: 116-123. (Pubitemid 34289498)
    • (2002) Hepato-Gastroenterology , vol.49 , Issue.43 , pp. 116-123
    • Griga, T.1    May, B.2    Pfisterer, O.3    Muller, K.-M.4    Brasch, F.5
  • 47
    • 13244263108 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and microvessel parameters of colonic mucosa correlate with sensitivity to steroid in patients with ulcerative colitis
    • DOI 10.1080/00365520410010580
    • Hanabata N, Sasaki Y, Tanaka M, et al. Vascular endothelial growth factor expression and microvessel parameters of colonic mucosa correlate with sensitivity to steroid in patients with ulcerative colitis. Scand J Gastroenterol. 2005; 40: 188-193. (Pubitemid 40188999)
    • (2005) Scandinavian Journal of Gastroenterology , vol.40 , Issue.2 , pp. 188-193
    • Hanabata, N.1    Sasaki, Y.2    Tanaka, M.3    Tsuji, T.4    Hatada, Y.5    Hada, R.6    Munakata, A.7
  • 50
    • 46049092017 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats
    • DOI 10.1002/ibd.20382
    • Ando Y, Inaba M, Sakaguchi Y, et al. Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. Inflamm Bowel Dis. 2008; 14: 826-838. (Pubitemid 351898068)
    • (2008) Inflammatory Bowel Diseases , vol.14 , Issue.6 , pp. 826-838
    • Ando, Y.1    Inaba, M.2    Sakaguchi, Y.3    Tsuda, M.4    Guo, K.Q.5    Omae, M.6    Okazaki, K.7    Ikehara, S.8
  • 51
    • 1642540081 scopus 로고    scopus 로고
    • Increased vascular endothelial growth factor production in fibroblasts isolated from strictures in patients with Crohn's disease
    • DOI 10.1002/bjs.4453
    • Beddy D, Watson RW, Fitzpatrick JM, et al. Increased vascular endothelial growth factor production in fibroblasts isolated from strictures in patients with Crohn's disease. Br J Surg. 2004; 91: 72-77. (Pubitemid 38122053)
    • (2004) British Journal of Surgery , vol.91 , Issue.1 , pp. 72-77
    • Beddy, D.1    Watson, R.W.G.2    Fitzpatrick, J.M.3    O'Connell, P.R.4
  • 52
    • 0842313181 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor (VEGF) - A Possible Mediator of Inflammation and Mucosal Permeability in Patients with Collagenous Colitis
    • DOI 10.1023/B:DDAS.0000011611.92440.f2
    • Taha Y, Raab Y, Larsson A, et al. Vascular endothelial growth factor (VEGF)-a possible mediator of inflammation and mucosal permeability in patients with collagenous colitis. Dig Dis Sci. 2004; 49: 109-115. (Pubitemid 38183754)
    • (2004) Digestive Diseases and Sciences , vol.49 , Issue.1 , pp. 109-115
    • Taha, Y.1    Raab, Y.2    Larsson, A.3    Carlson, M.4    Loof, L.5    Gerdir, B.6    Thorn, M.7
  • 54
    • 76149087164 scopus 로고    scopus 로고
    • Lymphangiogenesis and angiogenesis: Concurrence and/or dependence? Studies in inbred mouse strains
    • Nakao S, Maruyama K, Zandi S, et al. Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains. FASEB J. 2010; 24: 504-513.
    • (2010) FASEB J , vol.24 , pp. 504-513
    • Nakao, S.1    Maruyama, K.2    Zandi, S.3
  • 56
    • 34447257690 scopus 로고    scopus 로고
    • Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells
    • DOI 10.1016/j.ejca.2007.04.024, PII S0959804907003528
    • Matsuo M, Yamada S, Koizumi K, et al. Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells. Eur J Cancer. 2007; 43: 1748-1754. (Pubitemid 47042372)
    • (2007) European Journal of Cancer , vol.43 , Issue.11 , pp. 1748-1754
    • Matsuo, M.1    Yamada, S.2    Koizumi, K.3    Sakurai, H.4    Saiki, I.5
  • 60
    • 25444481287 scopus 로고    scopus 로고
    • Direct role of PDGF-BB in lymphangiogenesis and lymphatic metastasis
    • Cao Y., Direct role of PDGF-BB in lymphangiogenesis and lymphatic metastasis. Cell Cycle. 2005; 4: 228-230. (Pubitemid 41365322)
    • (2005) Cell Cycle , vol.4 , Issue.2 , pp. 228-230
    • Cao, Y.1
  • 61
    • 70349787149 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB reflects clinical, inflammatory and angiogenic disease activity and oxidative stress in inflammatory bowel disease
    • Krzystek-Korpacka M, Neubauer K, Matusiewicz M., Platelet-derived growth factor-BB reflects clinical, inflammatory and angiogenic disease activity and oxidative stress in inflammatory bowel disease. Clin Biochem. 2009; 42: 1602-1609.
    • (2009) Clin Biochem , vol.42 , pp. 1602-1609
    • Krzystek-Korpacka, M.1    Neubauer, K.2    Matusiewicz, M.3
  • 62
    • 0035677983 scopus 로고    scopus 로고
    • Platelet-derived growth factor and its receptors are expressed in areas of both active inflammation and active fibrosis in inflammatory bowel disease
    • DOI 10.1620/tjem.195.21
    • Kumagai S, Ohtani H, Nagai T, et al. Platelet-derived growth factor and its receptors are expressed in areas of both active inflammation and active fibrosis in inflammatory bowel disease. Tohoku J Exp Med. 2001; 195: 21-33. (Pubitemid 34036883)
    • (2001) Tohoku Journal of Experimental Medicine , vol.195 , Issue.1 , pp. 21-33
    • Kumagai, S.1    Ohtani, H.2    Nagai, T.3    Funa, K.4    Hiwatashi, N.5    Shimosegawa, T.6    Nagura, H.7
  • 63
    • 33644694009 scopus 로고    scopus 로고
    • The potential lymphangiogenic effects of hepatocyte growth factor/scatter factor in vitro and in vivo
    • Jiang WG, Davies G, Martin TA, et al. The potential lymphangiogenic effects of hepatocyte growth factor/scatter factor in vitro and in vivo. Int J Mol Med. 2005; 16: 723-728.
    • (2005) Int J Mol Med , vol.16 , pp. 723-728
    • Jiang, W.G.1    Davies, G.2    Martin, T.A.3
  • 64
    • 33646407806 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action
    • Cao R, Bjorndahl MA, Gallego MI, et al. Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action. Blood. 2006; 107: 3531-3536.
    • (2006) Blood , vol.107 , pp. 3531-3536
    • Cao, R.1    Bjorndahl, M.A.2    Gallego, M.I.3
  • 65
    • 30544452034 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes lymphatic vessel formation and function
    • DOI 10.1038/sj.emboj.7600763, PII 7600763
    • Kajiya K, Hirakawa S, Ma B, et al. Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J. 2005; 24: 2885-2895. (Pubitemid 43079892)
    • (2005) EMBO Journal , vol.24 , Issue.16 , pp. 2885-2895
    • Kajiya, K.1    Hirakawa, S.2    Ma, B.3    Drinnenberg, I.4    Detmar, M.5
  • 67
    • 70249129719 scopus 로고    scopus 로고
    • Growth factor manipulation of intestinal angiogenesis: A possible new paradigm in the management of inflammatory bowel disease
    • Thatch KA, Mendelson KG, Haber MM, et al. Growth factor manipulation of intestinal angiogenesis: a possible new paradigm in the management of inflammatory bowel disease. J Surg Res. 2009; 156: 245-249.
    • (2009) J Surg Res , vol.156 , pp. 245-249
    • Thatch, K.A.1    Mendelson, K.G.2    Haber, M.M.3
  • 68
    • 27944464966 scopus 로고    scopus 로고
    • Mucosal repair and growth factors: Recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease
    • DOI 10.1007/s00535-005-1705-x
    • Ido A, Numata M, Kodama M, et al. Mucosal repair and growth factors: recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease. J Gastroenterol. 2005; 40: 925-931. (Pubitemid 41662515)
    • (2005) Journal of Gastroenterology , vol.40 , Issue.10 , pp. 925-931
    • Ido, A.1    Numata, M.2    Kodama, M.3    Tsubouchi, H.4
  • 69
    • 1542284715 scopus 로고    scopus 로고
    • Roles of main pro- and anti-angiogenic factors in tumor angiogenesis
    • Huang Z, Bao SD., Roles of main pro- and anti-angiogenic factors in tumor angiogenesis. World J Gastroenterol. 2004; 10: 463-470. (Pubitemid 38325297)
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.4 , pp. 463-470
    • Huang, Z.1    Bao, S.-D.2
  • 70
    • 18644382318 scopus 로고    scopus 로고
    • Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1
    • Gale NW, Thurston G, Hackett SF, et al. Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1. Dev Cell. 2002; 3: 411-423.
    • (2002) Dev Cell , vol.3 , pp. 411-423
    • Gale, N.W.1    Thurston, G.2    Hackett, S.F.3
  • 73
    • 33947285048 scopus 로고    scopus 로고
    • Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2
    • Nguyen VP, Chen SH, Trinh J, et al. Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2. BMC Cell Biol. 2007; 8: 10.
    • (2007) BMC Cell Biol , vol.8 , pp. 10
    • Nguyen, V.P.1    Chen, S.H.2    Trinh, J.3
  • 74
    • 77952701611 scopus 로고    scopus 로고
    • Angiopoietin-2 in experimental colitis
    • Ganta VC, Cromer W, Mills GL, et al. Angiopoietin-2 in experimental colitis. Inflamm Bowel Dis. 2010; 16: 1029-1039.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1029-1039
    • Ganta, V.C.1    Cromer, W.2    Mills, G.L.3
  • 75
    • 33645065572 scopus 로고    scopus 로고
    • Potential role of soluble angiopoietin-2 and Tie-2 in patients with inflammatory bowel disease
    • Koutroubakis IE, Xidakis C, Karmiris K, et al. Potential role of soluble angiopoietin-2 and Tie-2 in patients with inflammatory bowel disease. Eur J Clin Invest. 2006; 36: 127-132.
    • (2006) Eur J Clin Invest , vol.36 , pp. 127-132
    • Koutroubakis, I.E.1    Xidakis, C.2    Karmiris, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.