The effect of probiotics on gastric mucosal permeability in humans administered with aspirin

Scandinavian Journal of Gastroenterology

Volumn 46, Issue 7-8, 2011, Pages 831-836

  Akama, Fumiaki ^a   Nishino, Ryo ^a   Makino, Seiya ^b   Kobayashi, Kiyoshi ^b   Kamikaseda, Kazufumi ^c   Nagano, Jun ^d   Koga, Yasuhiro ^a  

^a TOKAI UNIVERSITY   (Japan)

^b MEIJI DAIRIES CORPORATION   (Japan)

^c Kaizuka Hospital   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Aspirin; LG21; Permeability; Stomach; Stool occult blood

Indexed keywords

ACETYLSALICYLIC ACID; PROBIOTIC AGENT; SUCROSE;

ADULT; ARTICLE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MEGADOSE; FECES ANALYSIS; FEMALE; HUMAN; HUMAN EXPERIMENT; LACTOBACILLUS GASSERI; LOW DRUG DOSE; MALE; NORMAL HUMAN; OCCULT BLOOD TEST; PRIORITY JOURNAL; STOMACH MOTILITY; STOMACH MUCOSA; STOMACH MUCOSA PERMEABILITY; URINALYSIS; URINARY SUCROSE EXCRETION TEST;

ADULT; AGED; ASPIRIN; FEMALE; GASTRIC MUCOSA; HUMANS; LACTOBACILLUS; MALE; MIDDLE AGED; OCCULT BLOOD; PERMEABILITY; PROBIOTICS; SUCROSE;

EID: 79960213851     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2011.574730     Document Type: Article

References (11)

1. Patrono C, Garcia Rodriguez LA, Landolfi R, Baigent C. Low-dose aspirin for the prevention of atherothrombosis. N Engl J Med 2005;353:2373-83. (Pubitemid 41713749)
2. Somasundaram S, Hayllar H, Rafi S, Wrigglesworth JM, MaCpherson AJS, Bjarnason I. The biochemical basis of non-steroidal anti-inflammatory drug-induced damage to the gastrointestinal tract: a review and a hypothesis. Scand J Gastroenterol 1995;30:289-99.
3. Meddings JB, Sutherland LR, Byles NI, Wallace JL. Sucrose: a novel permeability marker for gastroduodenal disease. Gastroenterology 1993;104:1619-26. (Pubitemid 23235450)
4. Gotteland M, Cruchet S, Verbeke S. Effect of lactobacillus ingestion on the gastrointestinal mucosal barrier alterations induced by indometacin in humans. Aliment Pharmacol Ther 2001;15:11-7. (Pubitemid 32055581)
5. Schoen RT, Vender RJ. Mechanisms of nonsteroidal anti-inflammatory drug-induced gastric damage. Am J Med 1989; 86:449-58. (Pubitemid 19103913)
6. Patrono C, Coller B, FitzGerald GA, Hirsh J, Roth G. Platelet-active drugs: the relationship among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004; 126:Suppl:234S-64S. (Pubitemid 39297956)
7. Bjarnason I, Hayllar J, Macpherson AJ, Russel AS. Side effects of non-steroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 1993;104: 1832-47. (Pubitemid 23235480)
8. Sigthorsson G, Tibble J, Hayllar J, Menzies I,Macpherson A, Moots R, et al. Intestinal permeability and inflammation in patients on NSAIDs. Gut 1998;43:506-11. (Pubitemid 28462036)
9. Uchida M, Kurakazu K. Yogurt containing Lactobacillus gasseri OLL2716 exerts gastroprotective action against acute gastric lesion and antral ulcer in rats. J Pharmacol Sci 2004; 96:84-90. (Pubitemid 39318781)
10. Tamura A, Kumai H, Nakamichi N, Sugiyama T, Deguchi R, Takagi A, et al. Suppression of Helicobacter pylori-induced interleukin-8 production in vitro and within the gastric mucosa by a live Lactobacillus strain. J Gastroenterol Hepatol 2006;21:1399-406. (Pubitemid 44154707)
11. Irons GV, Kirsner JB. Routine chemical tests of the stool for occult blood: an evaluation. Am J Med Sci 1965;249:247-60.