Monitoring trends in dextromethorphan abuse using the National Poison Data System: 2000-2010

Clinical Toxicology

Volumn 49, Issue 5, 2011, Pages 409-415

  Wilson, Matthew D ^a,b   Ferguson, Rennie W ^b   Mazer, Maryann E ^b,c   Litovitz, Toby L ^b,c,d  

^a UNIVERSITY OF VIRGINIA   (United States)

^b National Capital Poison Center   (United States)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^d GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adolescent; Coricidin; Cough and cold medication; NPDS; Poison control; Substance abuse

Indexed keywords

ANTIHISTAMINIC AGENT; BENZODIAZEPINE DERIVATIVE; CANNABINOID; COCAINE; CORICIDIN; DEXTROMETHORPHAN; GUAIFENESIN; NARCOTIC ANALGESIC AGENT;

ADOLESCENT; ADULT; ADVERSE OUTCOME; ARTICLE; DISEASE SEVERITY; DRUG DEPENDENCE; EXPOSURE; GEOGRAPHIC DISTRIBUTION; HUMAN; MAJOR CLINICAL STUDY; PREVALENCE; SEX RATIO; SUBSTANCE ABUSE;

ADOLESCENT; ADULT; CHILD; DEXTROMETHORPHAN; FEMALE; HUMANS; INFORMATION SYSTEMS; MALE; PREVALENCE; SUBSTANCE-RELATED DISORDERS; TIME FACTORS; UNITED STATES;

EID: 79960209955     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2011.585429     Document Type: Article

References (27)

1. Schwartz RH. Adolescent abuse of dextromethorphan. Clin Pediatr (Phila) 2005; 44:565-568. (Pubitemid 41243485)
2. Boyer EW. Dextromethorphan abuse. Pediatr Emerg Care 2004; 20: 858-863. (Pubitemid 40039880)
3. Johnston LD, O ' Malley PM, Bachman JG, Schulenberg JE, et al. Monitoring the Future National Survey Results on Drug Use, 1975-2009: Volume I, Secondary School Students. Bethesda, MD: National Institutes of Health/National Institute on Drug Abuse; 2010.
4. US Department of Health and Human Services, Substance Abuse and Mental Health Services Administration. Results from the 2007 National Survey on Drug Use and Health: National Findings. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2008.
5. Chyka PA, Erdman AR, Manoguerra AS, Christianson G, Booze LL, Nelson LS, et al. Practice guideline: dextromethorphan poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol 2007; 45:662-677. (Pubitemid 47394415)
6. Taylor JA, Novack AH, Almquist JR, Rogers JE. Effi cacy of cough suppressants in children. J Pediatr 1993; 122:799-802. (Pubitemid 23134974)
7. Lee PCL, Jawad MS, Eccles R. Antitussive effi cacy of dextromethorphan in cough associated with acute upper respiratory tract infection. J Pharm Pharmacol 2000; 52:1137-1142.
8. K aplan B, Buchanan J, Krantz MJ. QTc prolongation due to dextromethorphan. Int J Cardiol 2010; 148:363-364. Epub 2010 Oct 13.
9. Logan BK, Goldfogel G, Hamilton R, Kuhlman J. Five deaths resulting from abuse of dextromethorphan sold over the internet. J Anal Toxicol 2009; 33:99-103.
10. Schwartz AR, Pizon AF, Brooks DE. Dextromethorphan-induced serotonin syndrome. Clin Toxicol 2008; 46:771-773.
11. Kirages TJ, Sule HP, Mycyk MB. Severe manifestations of Coricidin intoxication. Am J Emerg Med 2003; 21:473-475. (Pubitemid 37322884)
12. Miller SC. Dextromethorphan psychosis, dependence and physical withdrawal. Addict Biol 2005; 10:325-327. (Pubitemid 41759266)
13. Traynor K. Advisers vote against declaring dextromethorphan a controlled substance. Am J Health Syst Pharm 2010; 67:1788.
14. Bronstein AC, Spyker DA, Cantilena LR, Jr., Green JL, Rumack BH, Heard SE. 2007 Annual report of the American Association of Poison Control Centers ' National Poison Data System (NPDS): 25th Annual Report. Clin Toxicol 2008; 46:927-1057.
15. Banken JA, Foster H. Dextromethorphan: an emerging drug of abuse. Ann N Y Acad Sci 2008; 1139:402-411.
16. Bryner JK, Wang UK, Hui JW, Bedodo M, MacDougall C, Anderson IB. Dextromethorphan abuse in adolescence an increasing trend: 1999-2004. Arch Pediatr Adolesc Med 2006; 160:1217-1222. (Pubitemid 44901683)
17. Baker SD, Borys DJ. A possible trend suggesting increased abuse from Coricidin exposures reported to the Texas Poison Network: comparing 1998 to 1999. Vet Hum Toxicol 2002; 44:169-171. (Pubitemid 34556473)
18. Banerji S, Anderson IB. Abuse of Coricidin HBP cough & cold tablets: episodes recorded by a poison center. Am J Health Syst Pharm 2001; 58:1811-1814. (Pubitemid 32924229)
19. Ball JK, Skellan D. Emergency department visits involving dextromethorphan. The DAWN Report: Offi ce of Applied Statistics, Substance Abuse and Mental Health Services Administration. http://dawninfo.samhsa.gov/ pubs/shortreports/default.asp. Accessed 8 February 2011.
20. US Census Bureau (2000). Census 2000 Summary File 1. http://factfi nder2.census.gov. Accessed 10 February 2011.
21. US Census Bureau, Population Division. Annual Estimates of the Resident Population by Sex and Five-Year Age Groups for the United States: April 1, 2000 to July 1, 2009. http://factfi nder2. census.gov. Accessed 10 February 2011.
22. US Census (2010). Resident Population of the 50 States, the District of Columbia, and Puerto Rico: 2010 Census. http://2010. census.gov/news/press-kits/ apportionment/apport.html. Accessed 10 February 2011.
23. Bronstein AC, Spyker DA, Cantilena LR, Jr., Green JL, Rumack BH, Giffi n SL. 2009 Annual Report of the American Association of Poison Control Centers ' National Poison Data System (NPDS): 27th Annual Report. Clin Toxicol 2010; 48:979-1178.
24. Litovitz T, Benson BE, Youniss J, Metz E. Determinants of US poison center utilization. Clin Toxicol 2010; 48:449-457.
25. The Vaults of Erowid Archives. http://www.erowid.org/general/about/about- archives1.shtml. Accessed February 2011.
26. Kleine M. Overview of the September 14, 2010, DSaRM Advisory Committee Meeting to Discuss the Drug Enforcement Administration (DEA) Request for an Abuse Potential Evaluation and Scheduling Recommendation for Dextromethorphan (DXM). FDA Memorandum. 23 August 2010.
27. Partnership for a Drug Free America. The Partnership Attitude Tracking Study (PATS): Teens 2008 Report. www.doj.mt.gov/rxabuse/docs/2008PATSreport.pdf. Accessed 26 February 2011.