Combination perindopril/indapamide for the treatment of hypertension: A review

Expert Opinion on Pharmacotherapy

Volumn 12, Issue 11, 2011, Pages 1827-1833

  De Leeuw, Peter W ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Efficacy; Hypertension; Low dose combination; Outcome trials; Perindopril indapamide

Indexed keywords

ALBUMIN; ATENOLOL; ENALAPRIL; GLICLAZIDE; INDAPAMIDE; INDAPAMIDE PLUS PERINDOPRIL; PERINDOPRIL; PLACEBO;

ANTIHYPERTENSIVE ACTIVITY; ANTIHYPERTENSIVE THERAPY; AREA UNDER THE CURVE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; COUGHING; DEMENTIA; DIURETIC THERAPY; DRUG APPROVAL; DRUG CLEARANCE; DRUG INDUCED HEADACHE; DRUG METABOLISM; DRUG SAFETY; DRUG SYNTHESIS; DRUG TOLERABILITY; ESSENTIAL HYPERTENSION; FRACTURE; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; HYPOKALEMIA; ISCHEMIC HEART DISEASE; LOW DRUG DOSE; MONOTHERAPY; NATRIURESIS; NON INSULIN DEPENDENT DIABETES MELLITUS; RECOMMENDED DRUG DOSE; REVIEW; SINGLE DRUG DOSE; URINARY EXCRETION;

ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; DRUG COMBINATIONS; HUMANS; HYPERTENSION; INDAPAMIDE; PERINDOPRIL; RISK FACTORS;

EID: 79960205490     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2011.585638     Document Type: Review

References (35)

1. Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens 2009;27:2121-58
2. Alfakih K, Hall AS. Perindopril. Expert Opin Pharmacother 2006;12:63-71 (Pubitemid 43056423)
3. Sassard J, Bataillard A, McIntyre H. An overview of the pharmacology and clinical efficacy of indapamide sustained release. Fundam Clin Pharmacol 2005;19:637-45 (Pubitemid 43821998)
4. McClellan KJ, Markham A. Perindopril 2 mg/indapamide 0.625 mg. Fixed low-dose combination. Drugs 1999;58:297-304
5. Mourad JJ, Le Jeune S. Evaluation of high dose of perindopril/indapamide fixed combination in reducing blood pressure and improving end-organ protection in hypertensive patients. Curr Med Res Opin 2009;25:2271-80
6. Dickerson JE, Hingorani AD, Ashby MJ, et al. Optimisation of antihypertensive treatment by crossover rotation of four major classes. Lancet 1999;353:2008-13 (Pubitemid 29271745)
7. Macfadyen RJ, Lees KR, Reid JL. Perindopril. A review of its pharmacokinetics and clinical pharmacology. Drugs 1990;39(Suppl 1):49-63 (Pubitemid 20050797)
8. Pratt-Ubanama M, Oparil S. Thiazide and loop diuretics. In: McInnes G, editor. Clinical pharmacology and therapeutics of hypertension. Amsterdam: Elsevier BV; 2008. pp. 87-118
9. Schiavi P, Piraube C, Lachau-Durand S, et al. Pharmacokinetic evaluation of a potential interaction between perindopril and indapamide at steady-state after once daily administration. Am J Hypertens 1994;7:56A
10. Meyrier A, Dratwa M, Sennesael J, Lachaud-Pettiti V. Fixed low-dose perindopril-indapamide combination in hypertensive patients with chronic renal failure. Am J Hypertens 1998;11:1087-92 (Pubitemid 28451913)
11. Forette B. Fixed low-dose perindopril 2 mg/indapamide 0.625 mg combination in very elderly hypertensives [letter]. J Hum Hypertens 1999;13:211-13 (Pubitemid 29137437)
12. Wing LM, Arnolda LF, Harvey PJ, et al. Low-dose diuretic and/or dietary sodium restriction when blood pressure is resistant to ACE inhibitor. Blood Press 1998;7:299-307 (Pubitemid 29182819)
13. Matheson AJ, Cheer SM, Goa KL. Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension. Drugs 2001;61:1211-29 (Pubitemid 32661233)
14. Gosse P. Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection. Expert Rev Cardiovasc Ther 2006;4:319-33. (Pubitemid 43796990)
15. Mallion JM, Chamontin B, Asmar R, et al. Twenty-four-hour ambulatory blood pressure monitoring efficacy of perindopril/indapamide first-line combination in hypertensive patients: the REASON study. Am J Hypertens 2004;17:245-51 (Pubitemid 38293330)
16. de Luca N, Mallion JM, ORourke MF, et al. Regression of left ventricular mass in hypertensive patients treated with perindopril/indapamide as a first-line combination: the REASON echocardiography study. Am J Hypertens 2004;17:660-7 (Pubitemid 39091546)
17. Dahlof B, Gosse P, Gueret P, et al. Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study. J Hypertens 2005;23:2063-70 (Pubitemid 41830403)
18. Ghiadoni L, Magagna A, Kardasz I, et al. Fixed dose combination of perindopril and indapamide improves peripheral vascular function in essential hypertensive patients. Am J Hypertens 2009;22:506-12
19. Jin Y, Thijs L, Richart T, et al. Responses of the ambulatory arterial stiffness index and other measures of arterial function to antihypertensive drugs. Hypertens Res 2011;34:489-95
20. Mogensen CE, Viberti G, Halimi S, et al. Effect of low-dose perindopril/ indapamide on albuminuria in diabetes: preterax in albuminuria regression: PREMIER. Hypertension 2003;41:1063-71 (Pubitemid 36548604)
21. PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358:1033-41.
22. Staessen JA, Wang JG, Thijs L. Cardiovascular protection and blood pressure reduction: a meta-analysis. Lancet 2001;358:1305-15 (Pubitemid 33016494)
23. PROGRESS Collaborative Group. Effects of a perindopril-based blood pressure lowering regimen on cardiac outcomes among patients with cerebrovascular disease. Eur Heart J 2003;24:475-84
24. Arima H, Tzourio C, Anderson C, et al. Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trial. Stroke 2010;41:394-6
25. Perkovic V, Ninomiya T, Arima H, et al. Chronic kidney disease, cardiovascular events, and the effects of perindopril-based blood pressure lowering: data from the PROGRESS study. J Am Soc Nephrol 2007;18:2766-72 (Pubitemid 47531204)
26. Hayen A, Bell K, Glasziou P, et al. Monitoring adherence to medication by measuring change in blood pressure. Hypertension 2010;56:612-16.
27. The ADVANCE Collaborative Group. Rationale and design of the ADVANCE study: a randomised trial of blood pressure lowering and intensive glucose control in high-risk individuals with type 2 diabetes mellitus. Action in Diabetes and Vascular Disease: PreterAx and DiamicroN Modified-Release Controlled Evaluation. J Hypertens Suppl 2001;19:S21-8
28. Patel A, MacMahon S, Chalmers J, et al. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial. Lancet 2007;370:829-40. (Pubitemid 47362321)
29. Chalmers J, Arima H. Importance of blood pressure lowering in type 2 diabetes: focus on ADVANCE. J Cardiovasc Pharmacol 2010;55:340-7
30. Glasziou PP, Clarke P, Alexander J, et al. Cost-effectiveness of lowering blood pressure with a fixed combination of perindopril and indapamide in type 2 diabetes mellitus: an ADVANCE trial-based analysis. Med J Aust 2010;193:320-4
31. Beckett NS, Peters R, Fletcher AE, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008;358:1887-98. (Pubitemid 351620109)
32. Peters R, Beckett N, Forette F, et al. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol 2008;7:683-9
33. Bulpitt CJ, Beckett NS, Peters R, et al. Blood pressure control in the Hypertension in the Very Elderly Trial (HYVET). J Hum Hypertens 10 March 2011 [Epub ahead of print]
34. Peters R, Beckett N, Burch L, et al. The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET). Age Ageing 2010;39:609-16
35. Kang S, Wu YF, An N, Ren M. A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension. Clin Ther 2004;26:257-70. www.lareb.nl. [Last accessed 10 March 2010] (Pubitemid 38339017)