Effect of reversion of ganoderma lucidum polysaccharides on cisplatin resistant in ovarian cancer cells and its mechanism

Journal of Jilin University Medicine Edition

Volumn 37, Issue 2, 2011, Pages 250-254

  Qu, Hong Guang ^a,b   Gao, Lei ^a   He, Dan ^a   Liu, Cong ^c   Yan, Wei ^a   Gao, Song ^a   Wang, Li ^a  

^a Basic Medical College   (China)

^b Changchun Maternity Hospital   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Drug resistance genes; Ganoderma lucidum polysaccharides; SKOV 3 DDP

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CISPLATIN; GANODERMA LUCIDUM POLYSACCHARIDE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG INHIBITION; DRUG SENSITIVITY; GENE EXPRESSION; OVARY CANCER; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 79960202985     PISSN: 1671587X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Zhang HY, Zhang PN, Sun H. Aberration of the PI3K/AKT/mTOR signaling in epithelial ovarian cancer and its implication in cisplatin-based chemotherapy [J]. Eur J Obstet Gynecol Reprod Biol, 2009, 146(1): 81-86.
2. Watt PM. Screening for peptide drugs from the natural repertoire of biodiverse protein folds [J]. Nat Biotechnol, 2006, 24(2): 177-183. (Pubitemid 43221700)
3. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method [J]. Nat Protoc, 2008, 3(6): 1101-1108. (Pubitemid 351818697)
4. Tseng CP, Cheng AJ, Chang JT, et al. Quantitative analysis of multidrug-resistance mdr1 gene expression in head and neck cancer by real-time RT-PCR[J]. Jpn J Cancer Res, 2002, 93(11): 1230-1236. (Pubitemid 36032986)
5. Cao QZ, Lin ZB. Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide [J]. Acta Pharmacol Sin, 2004, 25(6): 833-838.
6. Chan WK, Cheung CC, Law HK, et al. Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function [J]. J Hematol Oncol, 2008, 1(9): 1-12.
7. Evsenko MS, Shashkow AS, Artonomova AV, et al. Polysaccharides of basidiomycetes. alkali-soluble polysaccharides from the mycelium of white rot fungus Ganoderma lucidum (Curt. : Fr.) P. Karst [J]. Biochemistry (Mosc), 2009, 74(5): 533-542.
8. Gao Y, Gao H, Chan E, et al. Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice [J]. Immunol Invest, 2005, 34(2): 171-198. (Pubitemid 40677457)
9. Gao Y, Tang W, Dai X, et al. Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer [J]. J Med Food, 2005, 8(2): 159-168. (Pubitemid 41008978)
10. Hsu JW, Huang HC, Chen ST, et al., Ganoderma lucidum polysaccharides induce macrophage-like differentiation in human leukemia THP-1 cells via caspase and p53 activation [J]. Evid Based Complement Alternat Med, 2009- 08-20[Epub ahead of print].
11. Jiang Y, Wang H, Lu L, et al. Chemistry of polysaccharide Lzps-1 from Ganoderma lucidum spore and anti-tumor activity of its total polysaccharides [J]. Yao Xue Xue Bao, 2005, 40(4): 347-350. (Pubitemid 40770057)
12. Liu G, Ding C, Zhang K, et al. Effects of medicinal insect, Catharsius molossus on biosynthesis of polysaccharides from Ganoderma lucidum in submerged culture [J]. Sheng Wu Gong Cheng Xue Bao, 2009, 25(6): 914-919.
13. Ma C, Guan SH, Yang M, et al. Differential protein expression in mouse splenic mononuclear cells treated with polysaccharides from spores of Ganoderma lucidum [J]. Phytomedicine, 2008, 15(4): 268-276.
14. Wang J, Zhang L, Yu YH, et al. Enhancement of antitumor activities in sulfated and carboxymethylated polysaccharides of Ganoderma lucidum [J]. J Agric Food Chem, 2009, 57(22): 10565-10572.