Do patients diagnosed with Alzheimer's disease benefit from a psycho-educational programme for family caregivers? A randomised controlled study

International Journal of Geriatric Psychiatry

Volumn 26, Issue 8, 2011, Pages 833-842

  De Rotrou, Jocelyne ^a   Cantegreil, Inge ^a   Faucounau, Véronique ^a   Wenisch, Emilie ^a   Chausson, Catherine ^a   Jegou, David ^b   Grabar, Sophie ^b   Rigaud, Anne Sophie ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b Cochin Hospital ^*  (France)

Author keywords

Alzheimer's disease management; cognitive stimulation; family caregivers; psycho educational program; psychosocial intervention

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; CAREGIVER; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; FEMALE; HEALTH PROGRAM; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PSYCHOEDUCATION; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SINGLE BLIND PROCEDURE; VISUAL ANALOG SCALE;

ADAPTATION, PSYCHOLOGICAL; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CAREGIVERS; DISABILITY EVALUATION; FEASIBILITY STUDIES; FEMALE; FRANCE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); PROGRAM EVALUATION; PSYCHIATRIC STATUS RATING SCALES;

EID: 79960199829     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2611     Document Type: Article

References (39)

1. Breuil V, De Rotrou J, Forette F, et al,. 1994. Cognitive stimulation of patients with dementia, preliminary results. Int J Geriatr Psychiatry 9: 211-217. (Pubitemid 24090354)
2. Brodaty H, Green A, Koschera A,. 2003. Meta-analysis of psychosocial interventions for caregivers of people with dementia. J Am Geriatr Soc 51: 657-664. (Pubitemid 36541430)
3. Clare L, Woods RT, Moniz Cook ED, et al,. 2003. Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev 4: CD003260.
4. Coudin G,. 2004. Family caregiver's reluctance toward community services: a social psychology perspective. Psychol Neuropsychiatr Vieil 2: 285-296.
5. Cummings JL, Mega MS, Gray K, et al,. 1994. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 44: 2308-2314. (Pubitemid 24382728)
6. De Rotrou J, Thévenet S, Audry G, et al,. 2006a. Images des aidants dans la Démence. In Images et Démence. Monographies du Groupe de Recherche sur l'Alzheimer, Michel BF, Verdureau F, Dubois B, (eds). Solal: Marseille; 207-218.
7. De Rotrou J, Thévenet S, Richard A, et al,. 2006b. Impact d'un programme psycho-éducatif sur le stress des aidants de patients Alzheimer. Encéphale 32: 650-655.
8. De Rotrou J, Wenisch E,. 2009. Stimulation cognitive et vieillissement. In Gérontologie préventive. Abrégés de Médecine. Masson: 468-483.
9. Dartigues J-F,. Efficacy assessment of three non-pharmacological therapies in Alzheimer's disease (ETNA3). Available at
10. Doody RS, Stevens JC, Beck C, et al,. 2001. Practice parameter: management of dementia (an evidence-based review). Report of the quality standards subcommittee of the American Academy of Neurology. Neurology 56: 1154-1166. (Pubitemid 32405709)
11. Gelinas I, Gauthier L, Mc Intyre M,. 1999. Development of a functional measure for persons with Alzheimer's disease: the disability assessment for dementia. Am J Occup Ther 53: 471-481.
12. Gitlin LN, Corcoran M, Winter L, et al,. 2001. A randomized, controlled trial of a home environmental intervention: effect on efficacy and upset in caregivers and on daily function of persons with dementia. Gerontologist 41: 4-14. (Pubitemid 32144172)
13. Graff M, Vernooij-Dassen M, Thijssen M, et al,. 2006. Community based occupational therapy for patients with dementia and their care givers: randomised controlled trial. BMJ 333: 1196.
14. Hakansson K, Rovio S, Helkala EL, et al,. 2009. Association between mid-life marital status and cognitive function in later life: population based cohort study. BMJ 339: b2462.
15. Haute Autorité de Santé. 2008. Prise en charge de la maladie d'Alzheimer et des maladies apparentées: interventions médicamenteuses et non médicamenteuses. Available at
16. Hébert R, Levesque L, Vezina J, et al,. 2003. Efficacy of a psychoeducative group program for caregivers of demented persons living at home: a randomized controlled trial. J Gerontol B Psychol Sci Soc Sci 58: S58-S67. (Pubitemid 36114807)
17. Lyons KS, Zarit SH, Sayer AG, Whitlatch CJ,. 2002. Caregiving as a dyadic process: perspectives from caregiver and receiver. J Gerontol Psychol Sci 57B: 195-204.
18. Mantha S, Thisted R, Foss J, et al,. 1993. A proposal to use confidence intervals for visual analogue scale data for pain measurement to determine clinical significance. Anesth Analg 77: 1041-1047. (Pubitemid 23319807)
19. Mc Khann G, Drachman D, Folstein M, et al,. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group on the hospices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34: 939-944. (Pubitemid 14076461)
20. Mittelman MS, Brodaty H, Wallen AS, Burns A,. 2008. A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression. Am J Geriatr Psychiatry 16: 893-904.
21. Mittelman MS, Ferris SH, Shulman E, et al,. 1995. A comprehensive support program: effect on depression in spouse-caregivers of AD patients. Gerontologist 35: 792-802.
22. Mittelman MS, Ferris SH, Shulman E, et al,. 1996. A family intervention to delay nursing home placement of patients with Alzheimer's disease: a randomized controlled trial. J Am Med Assoc 276: 1725-1731. (Pubitemid 26423964)
23. Mittelman MS, Roth DL, Coon DW, Haley WE,. 2004. Sustained benefit of supportive intervention for depressive symptoms in caregivers of patients with Alzheimer's disease. Am J Psychiatry 161: 850-856. (Pubitemid 38625338)
24. Montgomery SA, Asberg N,. 1979. A new depression scale designed to be sensitive to change. Br J Psychiatry 134: 382-389. (Pubitemid 9136500)
25. Norton MC, Piercy KW, Rabins PV, et al,. 2009. Caregiver-recipient closeness and symptom progression in Alzheimer disease. The cache county dementia progression study. J Gerontol Psychol Sci 64: 560-568.
26. Olazarán J, Muñiz R, Reisberg B, et al,. 2004. Benefits of cognitive-motor intervention in MCI and mild-to-moderate Alzheimer disease. Neurology 63: 2348-2353. (Pubitemid 40024348)
27. Pinquart M, Sörensen S,. 2006. Helping caregivers of persons with dementia: which interventions work and how large are their effects? Int Psychogeriatr 18: 577-595. (Pubitemid 44622993)
28. Price DD, McGrath PA, Rafii A, Buckingham B,. 1983. The validation of visual analogue scale as ratio scale measure for chronic and experimental pain. Pain 17: 45-56. (Pubitemid 13004473)
29. Rigaud A-S,. AIDMA, 2003. Contribution of a Psycho-Educational Program of help to helpers in pharmacological treatment of Alzheimer's disease. Available at
30. Rosen W, Mohs R, Davis KL,. 1984. A new rating scale for Alzheimer's disease. Am J Psychiatry 141: 1356-1364.
31. Smits CH, de Lange J, Droës RM, et al,. 2007. Effects of combined intervention programmes for people with dementia living at home and their caregivers: a systematic review. Int J Geriatr Psychiatry 22: 1183-1193.
32. Spector A, Thorgrimsen L, Woods B, et al,. 2003. Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia: randomised controlled trial. Br J Psychiatry 183: 248-254. (Pubitemid 37070181)
33. Ulstein I, Sandvik L, Wyller TB, Engedal K,. 2007. A one-year randomized controlled psychosocial intervention study among family carers of dementia patients. Effects on patients and carers. Dement Geriatr Cogn Disord 24: 469-475. (Pubitemid 350175908)
34. Van Duinen M, Rickelt J, Griez E,. 2008. Validation of the electronic visual analogue scale of anxiety. Prog Neuropsychopharmacol Biol Psychiatry 32: 1045-1047. (Pubitemid 351622091)
35. Vernooij-Dassen M, Kurz X, Scuvee-Moreau J, Dresse A,. 2003. The measure of sense of competence in caregivers of patients with dementia. Rev d'Epidémiol Santé Publique 51: 227-235. (Pubitemid 37464171)
36. Vernooij-Dassen M, Moniz-Cook ED, Woods RT, et al,. 2005. Factors affecting timely recognition and diagnosis of dementia across Europe: from awareness to stigma. Int J Geriatr Psychiatry 20: 377-386. (Pubitemid 40590500)
37. Vink AC, Birks JS, Bruinsma MS, Scholten RJ,. 2004. Music therapy for people with dementia. Cochrane database Syst Rev 3: CD003477.
38. Woods B, Spector A, Jones C, et al,. 2005. Reminiscence therapy for dementia. Cochrane Database Syst Rev 2: CD001120.
39. Zarit SH, Zarit JM,. 1987. The Memory and Behaviour Problems Checklist-1987R and the Burden Interview. Pensylvannia State University: University Park, PA.