Influence of tissue absorption and scattering on the depth dependent sensitivity of Raman fiber probes investigated by Monte Carlo simulations

Biomedical Optics Express

Volumn 2, Issue 3, 2011, Pages 520-533

  Reble, Carina ^a,b   Gersonde, Ingo ^a   Lieber, Chad A ^c   Helfmann, Jürgen ^a  

^a Laser und Medizin Technologie GmbH   (Germany)

^b TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^c CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFRARED DEVICES; MONTE CARLO METHODS; PROBES; SCATTERING; TISSUE;

DEPTH DEPENDENTS; FINGERPRINT SPECTRA; MONTE CARLO MODEL; MONTE CARLO SIMULATION; NEAR-INFRARED WAVELENGTH; NONMELANOMA SKIN; NORMAL SKIN; RAMAN FIBER; RAMAN PROBE; REDUCED SCATTERING COEFFICIENTS; SAMPLING VOLUME; SCATTERING CO-EFFICIENT; SINGLE FIBER; SKIN MODEL; TISSUE ABSORPTION; WAVELENGTH DEPENDENCY;

ABSORPTION SPECTROSCOPY;

EID: 79960199051     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.2.000520     Document Type: Article

References (39)

1. A. S. Haka, K. E. Shafer-Peltier, M. Fitzmaurice, J. Crowe, R. R. Dasari, and M. S. Feld, “Diagnosing breast cancer by using Raman spectroscopy,” Proc. Natl. Acad. Sci. U.S.A. 102(35), 12371-12376 (2005).
2. N. Stone, and P. Matousek, “Advanced transmission Raman spectroscopy: a promising tool for breast disease diagnosis,” Cancer Res. 68(11), 4424-4430 (2008).
3. M. D. Keller, E. M. Kanter, C. A. Lieber, S. K. Majumder, J. Hutchings, D. L. Ellis, R. B. Beaven, N. Stone, and A. Mahadevan-Jansen, “Detecting temporal and spatial effects of epithelial cancers with Raman spectroscopy,” Dis. Markers 25(6), 323-337 (2008).
4. C. A. Lieber, S. K. Majumder, D. L. Ellis, D. D. Billheimer, and A. Mahadevan-Jansen, “In vivo nonmelanoma skin cancer diagnosis using Raman microspectroscopy,” Lasers Surg. Med. 40(7), 461-467 (2008).
5. A. Nijssen, K. Maquelin, L. F. Santos, P. J. Caspers, T. C. Bakker Schut, J. C. den Hollander, M. H. Neumann, and G. J. Puppels, “Discriminating basal cell carcinoma from perilesional skin using high wave-number Raman spectroscopy,” J. Biomed. Opt. 12(3), 034004 (2007).
6. J. Mo, W. Zheng, J. J. H. Low, J. Ng, A. Ilancheran, and Z. Huang, “High wavenumber Raman spectroscopy for in vivo detection of cervical dysplasia,” Anal. Chem. 81(21), 8908-8915 (2009).
7. E. M. Kanter, E. Vargis, S. Majumder, M. D. Keller, E. Woeste, G. G. Rao, and A. Mahadevan-Jansen, “Application of Raman spectroscopy for cervical dysplasia diagnosis,” J Biophotonics 2(1-2), 81-90 (2009).
8. M. G. Shim, B. C. Wilson, E. Marple, and M. Wach, “Study of Fiber-Optic Probes for in Vivo Medical Raman Spectroscopy,” Appl. Spectrosc. 53(6), 619-627 (1999).
9. N. D. Magee, J. S. Villaumie, E. T. Marple, M. Ennis, J. S. Elborn, and J. J. McGarvey, “Ex vivo diagnosis of lung cancer using a Raman miniprobe,” J. Phys. Chem. B 113(23), 8137-8141 (2009).
10. R. O. P. Draga, M. C. M. Grimbergen, P. L. M. Vijverberg, C. F. P. van Swol, T. G. N. Jonges, J. A. Kummer, and J. L. H. Ruud Bosch, “In vivo bladder cancer diagnosis by high-volume Raman spectroscopy,” Anal. Chem. 82(14), 5993-5999 (2010).
11. J. T. Motz, M. Hunter, L. H. Galindo, J. A. Gardecki, J. R. Kramer, R. R. Dasari, and M. S. Feld, “Optical fiber probe for biomedical Raman spectroscopy,” Appl. Opt. 43(3), 542-554 (2004).
12. Z. Huang, S. K. Teh, W. Zheng, J. Mo, K. Lin, X. Shao, K. Y. Ho, M. Teh, and K. G. Yeoh, “Integrated Raman spectroscopy and trimodal wide-field imaging techniques for real-time in vivo tissue Raman measurements at endoscopy,” Opt. Lett. 34(6), 758-760 (2009).
13. J. Mo, W. Zheng, and Z. Huang, “Fiber-optic Raman probe couples ball lens for depth-selected Raman measurements of epithelial tissue,” Biomed. Opt. Express 1(1), 17-30 (2010).
14. P. Matousek, I. P. Clark, E. R. C. Draper, M. D. Morris, A. E. Goodship, N. Everall, M. Towrie, W. F. Finney, and A. W. Parker, “Subsurface probing in diffusely scattering media using spatially offset Raman spectroscopy,” Appl. Spectrosc. 59(4), 393-400 (2005).
15. N. Stone, R. Baker, K. Rogers, A. W. Parker, and P. Matousek, “Subsurface probing of calcifications with spatially offset Raman spectroscopy (SORS): future possibilities for the diagnosis of breast cancer,” Analyst (Lond.) 132(9), 899-905 (2007).
16. M. D. Keller, S. K. Majumder, and A. Mahadevan-Jansen, “Spatially offset Raman spectroscopy of layered soft tissues,” Opt. Lett. 34(7), 926-928 (2009).
17. P. Matousek, and N. Stone, “Emerging concepts in deep Raman spectroscopy of biological tissue,” Analyst (Lond.) 134(6), 1058-1066 (2009).
18. J. R. Maher, and A. J. Berger, “Determination of ideal offset for spatially offset Raman spectroscopy,” Appl. Spectrosc. 64(1), 61-65 (2010).
19. J. C. Day, R. Bennett, B. Smith, C. Kendall, J. Hutchings, G. M. Meaden, C. Born, S. Yu, and N. Stone, “A miniature confocal Raman probe for endoscopic use,” Phys. Med. Biol. 54(23), 7077-7087 (2009).
20. T. Katagiri, Y. S. Yamamoto, Y. Ozaki, Y. Matsuura, and H. Sato, “High axial resolution Raman probe made of a single hollow optical fiber,” Appl. Spectrosc. 63(1), 103-107 (2009).
21. T. J. Pfefer, K. T. Schomacker, M. N. Ediger, and N. S. Nishioka, “Multiple-fiber probe design for fluorescence spectroscopy in tissue,” Appl. Opt. 41(22), 4712-4721 (2002).
22. C. Zhu, Q. Liu, and N. Ramanujam, “Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation,” J. Biomed. Opt. 8(2), 237-247 (2003).
23. A. M. K. Enejder, T.-W. Koo, J. Oh, M. Hunter, S. Sasic, M. S. Feld, and G. L. Horowitz, “Blood analysis by Raman spectroscopy,” Opt. Lett. 27(22), 2004-2006 (2002).
24. P. Matousek, M. D. Morris, N. Everall, I. P. Clark, M. Towrie, E. Draper, A. Goodship, and A. W. Parker, “Numerical simulations of subsurface probing in diffusely scattering media using spatially offset Raman spectroscopy,” Appl. Spectrosc. 59(12), 1485-1492 (2005).
25. W. C. Shih, K. L. Bechtel, and M. S. Feld, “Intrinsic Raman spectroscopy for quantitative biological spectroscopy part I: theory and simulations,” Opt. Express 16(17), 12726-12736 (2008).
26. N. Everall, P. Matousek, N. MacLeod, K. L. Ronayne, and I. P. Clark, “Temporal and spatial resolution in transmission Raman spectroscopy,” Appl. Spectrosc. 64(1), 52-60 (2010).
27. M. D. Keller, R. H. Wilson, M.-A. Mycek, and A. Mahadevan-Jansen, “Monte Carlo model of spatially offset Raman spectroscopy for breast tumor margin analysis,” Appl. Spectrosc. 64(6), 607-614 (2010).
28. A. Ishimaru, “Wave Propagation and Scattering in Random Media,” IEEE Press, Oxford University Press: Oxford 1997.
29. C. Reble, I. Gersonde, S. Andree, H. J. Eichler, and J. Helfmann, “Quantitative Raman spectroscopy in turbid media,” J. Biomed. Opt. 15(3), 037016 (2010).
30. A. N. Bashkatov, E. A. Genina, V. I. Kochubey, and V. V. Tuchin, “Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000nm,” J. Phys. D Appl. Phys. 38(15), 2543-2555 (2005).
31. R. M. Doornbos, R. Lang, M. C. Aalders, F. W. Cross, and H. J. C. M. Sterenborg, “The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steady-state diffuse reflectance spectroscopy,” Phys. Med. Biol. 44(4), 967-981 (1999).
32. S. -H. Tseng, A. Grant, and A. J. Durkin, “In vivo determination of skin near-infrared optical properties using diffuse optical spectroscopy,” J. Biomed. Opt. 13(1), 014016 (2008).
33. G. Zonios, and A. Dimou, “Light scattering spectroscopy of human skin in vivo,” Opt. Express 17(3), 1256-1267 (2009).
34. S.-H. Tseng, P. Bargo, A. Durkin, and N. Kollias, “Chromophore concentrations, absorption and scattering properties of human skin in-vivo,” Opt. Express 17(17), 14599-14617 (2009).
35. S. Jacques, http://omlc.ogi.edu/news/jan98/skinoptics.html, last accessed 15.5.2010.
36. E. Salomatina, B. Jiang, J. Novak, and A. N. Yaroslavsky, “Optical properties of normal and cancerous human skin in the visible and near-infrared spectral range,” J. Biomed. Opt. 11(6), 064026 (2006).
37. H. Ding, J. Q. Lu, W. A. Wooden, P. J. Kragel, and X. H. Hu, “Refractive indices of human skin tissues at eight wavelengths and estimated dispersion relations between 300 and 1600 nm,” Phys. Med. Biol. 51(6), 1479-1489 (2006).
38. I. Barman, G. P. Singh, R. R. Dasari, and M. S. Feld, “Turbidity-corrected Raman spectroscopy for blood analyte detection,” Anal. Chem. 81(11), 4233-4240 (2009).
39. R. Steponavicius, and S. N. Thennadil, “Extraction of chemical information of suspensions using radiative transfer theory to remove multiple scattering effects: application to a model two-component system,” Anal. Chem. 81(18), 7713-7723 (2009).