Imatinib induced facial skin hyperpigmentation in a case of chronic myelogenous leukemia

Shiraz E Medical Journal

Volumn 12, Issue 3, 2011, Pages 162-164

  Valizadeh, N ^a  

^a URMIA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Chloasma; Hyperpigmentation; Imatinib; Skin

Indexed keywords

IMATINIB;

ABDOMINAL PAIN; ADULT; ARTICLE; BLOOD TRANSFUSION; BONE MARROW BIOPSY; CASE REPORT; CHRONIC MYELOID LEUKEMIA; CYTOGENETICS; DIZZINESS; DRUG INDUCED DISEASE; FACE HYPERPIGMENTATION; FALLING; HUMAN; HYPERPIGMENTATION; LABORATORY TEST; LAPAROTOMY; MALE; OPIATE ADDICTION; ORTHOSTATIC HYPOTENSION; PALLOR; PHILADELPHIA 1 CHROMOSOME; PHYSICAL EXAMINATION; SINUS TACHYCARDIA; SPLEEN RUPTURE; SPLENECTOMY; SPLENOMEGALY; SWEATING; TACHYCARDIA; TREATMENT RESPONSE;

EID: 79960185304     PISSN: 17351391     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Alexandrescu D T, Dasanu C A, Farzan-mehr H, Kauffman C L. Persistent cutaneous hyperpigmentation after tyrosine kinase in-hibition with imatinib for GIST. Dermatology Online Journal.2008; 14 (7): 7
2. Up to date 17.3, 2009.Drug information: Imatinib.
3. O'Brien SG, Guilhot F, Larson RA, Gath-mann I, Baccarani M, Cervantes F,et al.Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic phase chronic myeloid leukemia. N Engl J Med 2003; 348: 994-1004
4. Arora B, Kumar L, Sharma, Wadhwa J, Kochupillai V. Pigmentary changes in chronic myeloid leukemia patients treated with imatinib mesylate. Ann Oncol 2004; 15: 358-9.
5. Hui H, Yang-yang Y, Yu-houng W, Imatinib mesylate-induced repigmentation of vitiligo lesions in a patient with recurrent gastroin-testinal stromal tumors. JAAD.2008; 59 (5): S80-83
6. Prabhash K, Biswas Gh, Prasad N, Karant N, Sastry PS, Parikh PM. Imatinib-induced nail hyperpigmentation in chronic myeloid leukemia. Indian J Dermatol Venereol Leprol. 2006; 72 (1): 63-4
7. Singh N, Bakhshi S. Imatinib-induced dental hyperpigmentation in childhood chronic myeloid leukemia. J Pediatr Hematol Oncol. 2007; 29 (3): 208-9
8. Tsao AS, Kantarjian H, Cortes J, O'Brien S, Talpaz M. Imatinib mesylate causes hy-popigmentation in the skin.Cancer.2003; 98: 2483-7.