Comminution of ibuprofen to produce nano-particles for rapid dissolution

International Journal of Pharmaceutics

Volumn 415, Issue 1-2, 2011, Pages 307-314

  Plakkot, S ^a   De Matas, M ^a   York, P ^a   Saunders, M ^b   Sulaiman, B ^c  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b Kuecept Drug Delivery Technologies   (United Kingdom)

^c Dena Technology Ltd   (United Kingdom)

Author keywords

Comminution; Dissolution; Ibuprofen; Nano particles; Nano suspension; Spray drying

Indexed keywords

IBUPROFEN; MANNITOL; NANOPARTICLE;

ARTICLE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; NANOTECHNOLOGY; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; ROOM TEMPERATURE; SPRAY DRYING; SUSPENSION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLIZATION; DRUG COMPOUNDING; DRUG STABILITY; DRUG STORAGE; IBUPROFEN; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; POWDER DIFFRACTION; POWDERS; SOLUBILITY; SURFACE PROPERTIES; SUSPENSIONS; X-RAY DIFFRACTION;

EID: 79960163552     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.06.002     Document Type: Article

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