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Volumn 21, Issue 7, 2011, Pages 1080-1087

Combinatory action of VEGFR2 and MAP kinase pathways maintains endothelial-cell integrity

Author keywords

endothelial cell integrity; PP1; vascular lumen; zebrafish

Indexed keywords

4 AMINO 5 (4 METHYLPHENYL) 7 (TERT BUTYL)PYRAZOLO(3,4 D)PYRIMIDINE; 4-AMINO-5-(4-METHYLPHENYL)-7-(TERT-BUTYL)PYRAZOLO(3,4-D)PYRIMIDINE; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; VASCULOTROPIN RECEPTOR 2;

EID: 79960148768     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.41     Document Type: Article
Times cited : (9)

References (29)
  • 1
    • 33747139066 scopus 로고    scopus 로고
    • Endothelial tubes assemble from intracellular vacuoles in vivo
    • DOI 10.1038/nature04923, PII NATURE04923
    • Kamei M, Saunders WB, Bayless KJ, Dye L, Davis GE, Weinstein BM. Endothelial tubes assemble from intracellular vacuoles in vivo. Nature 2006; 442:453-456. (Pubitemid 44264794)
    • (2006) Nature , vol.442 , Issue.7101 , pp. 453-456
    • Kamei, M.1    Brian Saunders, W.2    Bayless, K.J.3    Dye, L.4    Davis, G.E.5    Weinstein, B.M.6
  • 2
    • 41149157843 scopus 로고    scopus 로고
    • Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo
    • Blum Y, Belting HG, Ellertsdottir E, Herwig L, Lüders F, Affolter M. Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo. Dev Biol 2008; 316:312-322.
    • (2008) Dev. Biol. , vol.316 , pp. 312-322
    • Blum, Y.1    Belting, H.G.2    Ellertsdottir, E.3    Herwig, L.4    Lüders, F.5    Affolter, M.6
  • 3
    • 77951227371 scopus 로고    scopus 로고
    • Vascular morphogenesis in the zebrafish embryo
    • Ellertsdottir E, Lenard A, Blum Y, et al. Vascular morphogenesis in the zebrafish embryo. Dev Biol 2010; 341:56-65.
    • (2010) Dev. Biol. , vol.341 , pp. 56-65
    • Ellertsdottir, E.1    Lenard, A.2    Blum, Y.3
  • 4
    • 70349997561 scopus 로고    scopus 로고
    • The molecular basis of vascular lumen formation in the developing mouse aorta
    • Strilic B, Kucera T, Eglinger J, et al. The molecular basis of vascular lumen formation in the developing mouse aorta. Dev Cell 2009; 17:505-515.
    • (2009) Dev. Cell , vol.17 , pp. 505-515
    • Strilic, B.1    Kucera, T.2    Eglinger, J.3
  • 5
    • 0033847194 scopus 로고    scopus 로고
    • 1 integrins
    • Bayless KJ, Salazar R, Davis GE. RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins. Am J Pathol 2000; 156:1673-1683. (Pubitemid 30646705)
    • (2000) American Journal of Pathology , vol.156 , Issue.5 , pp. 1673-1683
    • Bayless, K.J.1    Salazar, R.2    Davis, G.E.3
  • 6
    • 0037087648 scopus 로고    scopus 로고
    • The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices
    • Bayless KJ, Davis GE. The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices. J Cell Sci 2002; 115(Pt 6):1123-1136. (Pubitemid 34272478)
    • (2002) Journal of Cell Science , vol.115 , Issue.6 , pp. 1123-1136
    • Bayless, K.J.1    Davis, G.E.2
  • 7
    • 0005170476 scopus 로고    scopus 로고
    • An integrin and Rho GTPase-dependent pinocytic vacuole mechanism controls capillary lumen formation in collagen and fibrin matrices
    • DOI 10.1038/sj.mn.7800175
    • Davis GE, Bayless KJ. An integrin and Rho GTPase-dependent pinocytic vacuole mechanism controls capillary lumen formation in collagen and fibrin matrices. Microcirculation 2003; 10:27-44. (Pubitemid 39004235)
    • (2003) Microcirculation , vol.10 , Issue.1 , pp. 27-44
    • Davis, G.E.1    Bayless, K.J.2
  • 8
    • 59649104201 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of vascular lumen formation
    • Iruela-Arispe ML, Davis GE. Cellular and molecular mechanisms of vascular lumen formation. Dev Cell 2009; 16:222-231.
    • (2009) Dev. Cell , vol.16 , pp. 222-231
    • Iruela-Arispe, M.L.1    Davis, G.E.2
  • 9
    • 0035865186 scopus 로고    scopus 로고
    • The vascular anatomy of the developing zebrafish: An atlas of embryonic and early larval development
    • DOI 10.1006/dbio.2000.9995
    • Isogai S, Horiguchi M, Weinstein BM. The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev Biol 2001; 230:278-301. (Pubitemid 32171423)
    • (2001) Developmental Biology , vol.230 , Issue.2 , pp. 278-301
    • Isogai, S.1    Horiguchi, M.2    Weinstein, B.M.3
  • 10
    • 0036337541 scopus 로고    scopus 로고
    • Patterning of angiogenesis in the zebrafish embryo
    • Childs S, Chen JN, Garrity DM, Fishman MC. Patterning of angiogenesis in the zebrafish embryo. Development 2002; 129:973-982. (Pubitemid 34874121)
    • (2002) Development , vol.129 , Issue.4 , pp. 973-982
    • Childs, S.1    Chen, J.-N.2    Garrity, D.M.3    Fishman, M.C.4
  • 11
    • 0028810741 scopus 로고
    • Cloche an early acting zebrafish gene is required by both the endothelial and hematopoietic lineages
    • Stainier DY, Weinstein BM, Detrich HW 3rd, Zon LI, Fishman MC. Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development 1995; 121:3141-3150.
    • (1995) Development , vol.121 , pp. 3141-3150
    • Stainier, D.Y.1    Weinstein, B.M.2    Detrich III, H.W.3    Zon, L.I.4    Fishman, M.C.5
  • 13
    • 77951621138 scopus 로고    scopus 로고
    • MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis
    • Nicoli S, Standley C, Walker P, Hurlstone A, Fogarty KE, Lawson ND. MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis. Nature 2010; 464:1196-1200.
    • (2010) Nature , vol.464 , pp. 1196-1200
    • Nicoli, S.1    Standley, C.2    Walker, P.3    Hurlstone, A.4    Fogarty, K.E.5    Lawson, N.D.6
  • 14
    • 0030029143 scopus 로고    scopus 로고
    • Discovery of a novel potent and Src family-selective tyrosine kinase inhibitor study of Lck- an FynT-dependent T cell activation
    • Hanke JH, Gardner JP, Dow RL, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- an FynT-dependent T cell activation. J Biol Chem 1996; 271:695-701.
    • (1996) J. Biol. Chem. , vol.271 , pp. 695-701
    • Hanke, J.H.1    Gardner, J.P.2    Dow, R.L.3
  • 16
    • 0036547763 scopus 로고    scopus 로고
    • Role of Src in signal transduction pathways the jubilee lecture
    • Courtneidge SA. Role of Src in signal transduction pathways. The Jubilee Lecture. Biochem Soc Trans 2002; 30:11-17.
    • (2002) Biochem. Soc. Trans. , vol.30 , pp. 11-17
    • Courtneidge, S.A.1
  • 17
    • 20044370091 scopus 로고    scopus 로고
    • Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements
    • DOI 10.1038/sj.embor.7400386
    • Jopling C, den Hertog J. Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements. EMBO Rep 2005; 6:426-431. (Pubitemid 40767075)
    • (2005) EMBO Reports , vol.6 , Issue.5 , pp. 426-431
    • Jopling, C.1    Den Hertog, J.2
  • 18
    • 38049018155 scopus 로고    scopus 로고
    • A quantitative analysis of kinase inhibitor selectivity
    • Karaman MW, Herrgard S, Treiber DK, et al. A quantitative analysis of kinase inhibitor selectivity. Nat Biotechnol 2008; 26:127-132.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 127-132
    • Karaman, M.W.1    Herrgard, S.2    Treiber, D.K.3
  • 19
    • 33947416658 scopus 로고    scopus 로고
    • Sunitinib: A VEGF and PDGF receptor protein kinase and angiogenesis inhibitor
    • Roskoski R Jr. Sunitinib: a VEGF and PDGF receptor protein kinase and angiogenesis inhibitor. Biochem Biophys Res Commun 2007; 356:323-328.
    • (2007) Biochem. Biophys. Res. Commun. , vol.356 , pp. 323-328
    • Roskoski, R.1
  • 20
    • 54249162351 scopus 로고    scopus 로고
    • Targeted polypharmacology: Discovery of dual inhibitors of tyrosine and phosphoinositide kinases
    • Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol 2008; 4:691-699.
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 691-699
    • Apsel, B.1    Blair, J.A.2    Gonzalez, B.3
  • 24
    • 33745646792 scopus 로고    scopus 로고
    • Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling
    • DOI 10.1016/j.cub.2006.05.046, PII S0960982206016290
    • Hong CC, Peterson QP, Hong JY, Peterson RT. Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling. Curr Biol 2006; 16:1366-1372. (Pubitemid 43975369)
    • (2006) Current Biology , vol.16 , Issue.13 , pp. 1366-1372
    • Hong, C.C.1    Peterson, Q.P.2    Hong, J.-Y.3    Peterson, R.T.4
  • 25
    • 77951160785 scopus 로고    scopus 로고
    • ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish
    • Ren B, Deng Y, Mukhopadhyay A, et al. ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish. J Clin Invest 2010; 120:1217-1228.
    • (2010) J. Clin. Invest , vol.120 , pp. 1217-1228
    • Ren, B.1    Deng, Y.2    Mukhopadhyay, A.3
  • 27
    • 0242331176 scopus 로고    scopus 로고
    • Selective Inhibition of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Identifies a Central Role for VEGFR-2 in Human Aortic Endothelial Cell Responses to VEGF
    • DOI 10.1081/RRS-120025567
    • Endo A, Fukuhara S, Masuda M, Ohmori T, Mochizuki N. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF. J Recept Signal Transduct Res 2003; 23:239-254. (Pubitemid 37362243)
    • (2003) Journal of Receptors and Signal Transduction , vol.23 , Issue.2-3 , pp. 239-254
    • Endo, A.1    Fukuhara, S.2    Masuda, M.3    Ohmori, T.4    Mochizuki, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.