Single nucleotide polymorphism (SNP) analysis demonstrates a significant association of tumour necrosis factor-alpha (TNFA) with primary immune thrombocytopenia among Caucasian adults

Hematology

Volumn 16, Issue 4, 2011, Pages 243-248

  Sarpatwari, Ameet ^a,b   Bussel, James B ^c   Ahmed, Momin ^b   Erqou, Sebhat ^a   Semple, John W ^d   Newland, Adrian C ^b   Bennett, Dimitri ^e   Pharoah, Paul ^a   Provan, Drew ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e GLAXOSMITHKLINE   (United States)

Author keywords

Cytokine or cytokine receptor genes; Primary immune thrombocytopenia (ITP); Single nucleotide polymorphisms (SNPs)

Indexed keywords

CYTOKINE RECEPTOR; IMMUNOGLOBULIN; PREDNISOLONE; RHESUS D ANTIBODY; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE REGISTRY; DISEASE SEVERITY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; HELICOBACTER INFECTION; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IL10 GENE; IL1A GENE; IL4R GENE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TGFB1 GENE; TNFA GENE;

ADULT; ALLELES; CASE-CONTROL STUDIES; CYTOKINES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CYTOKINE; THROMBOCYTOPENIA; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 79960139310     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453311X13025568941808     Document Type: Article

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