A review of biopsychosocial strategies to prevent and overcome early-recognized poor adherence in growth hormone therapy of children

Journal of Medical Economics

Volumn 14, Issue 4, 2011, Pages 448-457

  Haverkamp, Fritz ^a,b   Gasteyger, Christoph ^c  

^a BOCHUM UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c MERCK SERONO S A   (Switzerland)

Author keywords

Adherence; Adherence intervention; Growth hormone; Pediatric

Indexed keywords

GROWTH HORMONE;

CHRONIC DISEASE; DEVICE; EMOTION; FAMILY; GROWTH HORMONE DEFICIENCY; HEALTH CARE COST; HORMONAL THERAPY; HUMAN; PATIENT COMPLIANCE; PATIENT COUNSELING; PATIENT EDUCATION; REVIEW; SOCIAL ASPECT; SOCIOECONOMICS;

BODY HEIGHT; CHILD; COUNSELING; DRUG ADMINISTRATION SCHEDULE; FAMILY RELATIONS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMAN GROWTH HORMONE; HUMANS; INJECTIONS, SUBCUTANEOUS; MEDICATION ADHERENCE; RECOMBINANT PROTEINS; SOCIOECONOMIC FACTORS;

EID: 79960134177     PISSN: 13696998     EISSN: 1941837X     Source Type: Journal    
DOI: 10.3111/13696998.2011.590829     Document Type: Review

References (47)

1. Seeley RD, Stephens TD, Tate P. Anatomy and Physiology, 8th edn. New York: McGraw-Hill, 2008
2. Bowlby DA, Rapaport R. Safety and efficacy of growth hormone therapy in childhood. Pediatr Endocrinol Rev 2004;2(Suppl 1):68-77 (Pubitemid 40129185)
3. Clayton PE, Cuneo RC, Juul A, et al. Consensus statement on the management of the GH-treated adolescent in the transition to adult care. Eur J Endocrinol 2005;152:165-70 (Pubitemid 40309560)
4. Wilson TA, Rose SR, Cohen P, et al. Update of guidelines for the use of growth hormone in children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee. J Pediatr 2003;143:415-21 (Pubitemid 37355966)
5. Kornreich L, Horev G, Lazar L, et al. MR findings in hereditary isolated growth hormone deficiency. AJNR Am J Neuroradiol 1997;18:1743-7 (Pubitemid 30399778)
6. Norgren S. Adherence remains a challenge for patients receiving growth hormone therapy. Pediatr Endocrinol Rev 2009;6(Suppl 4):545-8
7. Engel GL. The need for a new medical model: a challenge for biomedicine. Science 1977;196:129-36 (Pubitemid 8067676)
8. Haynes RB, Ackloo E, Sahota N, et al. Interventions for enhancing medication adherence. Cochrane Database of Syst Rev 2008, Issue 2; doi: 10.1002/14651858.CD000011.pub3 (Pubitemid 351807324)
9. Vermeire E, Hearnshaw H, Van Royen P, et al. Patient adherence to treatment: three decades of research. A comprehensive review. J Clin Pharm Ther 2001;26:331-42 (Pubitemid 32989555)
10. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005;353:487-97 (Pubitemid 41127293)
11. World Health Organization. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization, 2003
12. Gold DT, McClung B. Approaches to patient education: emphasizing the long-term value of compliance and persistence. Am J Med 2006; 119(4 Suppl 1):S32-7
13. Haverkamp F, Johansson L, Dumas H, et al. Observations of nonadherence to recombinant human growth hormone therapy in clinical practice. Clin Ther 2008;30:307-16 (Pubitemid 351474387)
14. Stanhope R, Moyle L, MacSwiney M. Patient knowledge and compliance with growth hormone treatment. Arch Dis Child 1993;68:525 (Pubitemid 23136666)
15. Desrosiers P, OBrien F, Blethen S. Patient outcomes in the GHMonitor: the effect of delivery device on compliance and growth. Pediatr Endocrinol Rev 2005;2(Suppl 3):327-31 (Pubitemid 40469491)
16. Kapoor RR, Burke SA, Sparrow SE, et al. Monitoring of concordance in growth hormone therapy. Arch Dis Child 2008;93:147-8 (Pubitemid 351204756)
17. Oyarazabal M, Aliaga M, Chueca M, et al. Multicentre survey on compliance with growth hormone therapy: what can be improved? Acta Pediatr 1998;87:387-91 (Pubitemid 28252276)
18. Cramer J, Rosenheck R, Kirk G, et al. Medication compliance feedback and monitoring in a clinical trial: predictors and outcomes. Value Health 2003;6:566-73 (Pubitemid 37187719)
19. Haynes RB, McDonald HP, Garg AX. Helping patients follow prescribed treatment: clinical applications. JAMA 2002;288:2880-3 (Pubitemid 35425074)
20. Jackevicius CA, Mamdani M, Tu JV. Adherence with statin therapy in elderly patients with and without acute coronary syndromes. JAMA 2002; 288:462-7 (Pubitemid 34787477)
21. Rosenfeld RG, Bakker B. Compliance and persistence in pediatric and adult patients receiving growth hormone therapy. Endocr Pract 2008;14:143-54
22. Lee JM, Davis MM, Clark SJ, et al. Estimated cost-effectiveness of growth hormone therapy for idiopathic short stature. Arch Pediatr Adolesc Med 2006;160:263-9 (Pubitemid 43374359)
23. Blethen SL, Baptista J, Kuntze J, et al. Adult height in growth hormone (GH)-deficient children treated with biosynthetic GH. The Genentech Growth Study Group. J Clin Endocrinol Metab 1997;82:418-20 (Pubitemid 27068604)
24. Bakker B, Frane J, Anhalt H, et al. Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children. J Clin Endocrinol Metab 2008;93:352-7 (Pubitemid 351240802)
25. GH Research Society. Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: summary statement of the GH Research Society. J Clin Endocrinol Metab 2000;85:3990-3
26. Kirk J. Improving adherence to GH therapy with an electronic device: first experience with easypod. Pediatr Endocrinol Rev 2009; (6 Suppl 4):549-52
27. Kirk J. Developments in growth hormone delivery. Drug Deliv Ther 2010;5:43-7
28. Dahlgren J, Veimo D, Johansson L, et al. Patient acceptance of a novel electronic auto-injector device to administer recombinant human growth hormone: results from an open-label, user survey of everyday use. Curr Med Res Opin 2007;23:1649-55 (Pubitemid 47122174)
29. Fernández-Pérez L, Nóvoa J, Ståhlberg N, et al. The effect of in vivo growth hormone treatment on blood gene expression in adults with growth hormone deficiency reveals potential biomarkers to monitor growth hormone therapy. Clin Endocrinol 2010; 72:800-6
30. Christensen T, Fidler C, Bentley A, et al. The cost-effectiveness of somatropin treatment for short children born small for gestational age (SGA) and children with growth hormone deficiency (GHD) in Sweden. J Med Econ 2010; 13:168-78
31. Haverkamp F, Noeker M. Short stature in children-a questionnaire for parents: a new instrument for growth disorder-specific psychosocial adaptation in children. Qual Life Res 1998;7:447-55 (Pubitemid 28343453)
32. Haverkamp F, Eiholzer U, Ranke MB, et al. Symptomatic versus substitution growth hormone therapy in small children: from auxology towards a comprehensive multidimensional assessment of short stature and related interventions. J Pediatr Endocrinol Metab 2000;13:403-8 (Pubitemid 30202256)
33. Noeker M, Haverkamp F. Adjustment in conditions with short stature: a conceptual framework. J Pediatr Endocrinol Metab 2000; 13:1585-94 (Pubitemid 32044741)
34. Vrijens B, Vincze G, Kristanto P, et al. Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories. BMJ 2008;336:1114-17 (Pubitemid 351731741)
35. Modi AC, Morita DA, Glauser TA. One-month adherence in children with newonset epilepsy: white-coat compliance does not occur. Pediatrics 2008;12:e961-6
36. McDonald HP, Garg AX, Haynes RB. Interventions to enhance patient adherence to medication prescriptions: scientific review. JAMA 2002; 288:2868-79 (Pubitemid 35425073)
37. Smith SL, Hindmarsh PC, Brook CG. Compliance with growth hormone treatment-are they getting it? Arch Dis Child 1993;68:91-3 (Pubitemid 23039305)
38. Costello K, Kennedy P, Scanzillo J. Recognizing nonadherence in patients with multiple sclerosis and maintaining treatment adherence in the long term. Medscape J Med 2008;10:225
39. Cox D, Stone J. Managing self-injection difficulties in patients with relapsingremitting multiple sclerosis. J Neurosci Nurs 2006;38:167-71
40. Wickramasuriya BP, Casey A, Akhtar S et al. Factors determining patient choice of device for GH therapy. Horm Res 2006;65:18-22 (Pubitemid 43177313)
41. Ahmed SF, Smith WA, Blamires C. Facilitating and understanding the familys choice of injection device for growth hormone therapy by using conjoint analysis. Arch Dis Child 2008;93:110-14 (Pubitemid 351204749)
42. Dumas H, Panayiotopoulos P, Parker D, et al. Understanding and meeting the needs of those using growth hormone injection devices. BMC Endocr Disord 2006;6:5
43. Bozzola M, Colle M, Halldin-Stenlid M, et al. Treatment adherence with the easypod TM growth hormone electronic auto-injector and patient acceptance: survey results from 824 children and their parents. BMC Endocr Disord 2011;11:4
44. Arbuthnott A, Sharpe D. The effect of physician-patient collaboration on patient adherence in non-psychiatric medicine. Patient Educ Couns 2009;77:60-7
45. Cutfield WS, Derraik JGB, Gunn AJ, et al. Non-compliance with growth hormone treatment in children is common and impairs linear growth. PLoS One 2011;6:e16223
46. Chapman RH, Ferrufino CP, Kowal SL, et al. The cost and effectiveness of adherence-improving interventions for antihypertensive and lipid-lowering drugs. Int J Clin Pract 2010;64:16-81
47. Fielding D, Duff A. Compliance with treatment protocols: interventions for children with chronic illness. Arch Dis Child 1999;80:196-200 (Pubitemid 29119740)