Serum ferritin correlates with activity of anti-MDA5 antibody-associated acute interstitial lung disease as a complication of dermatomyositis

Modern Rheumatology

Volumn 21, Issue 2, 2011, Pages 223-227

  Gono, Takahisa ^a   Kawaguchi, Yasushi ^a   Ozeki, Eri ^a   Ota, Yuko ^a   Satoh, Takashi ^b   Kuwana, Masataka ^b   Hara, Masako ^a   Yamanaka, Hisashi ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Acute interstitial pneumonia; Dermatomyositis; Ferritin; Macrophage activation; Melanoma differentiation associated gene 5

Indexed keywords

ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; CANCER ANTIBODY; CREATINE KINASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN; INTERLEUKIN 8; MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5 ANTIBODY; METHYLPREDNISOLONE; PREDNISOLONE; TACROLIMUS; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ACUTE DISEASE; ADULT; AGED; AMYOPATHIC DERMATOMYOSITIS; ARTICLE; BLOOD GAS ANALYSIS; CASE REPORT; CLINICAL EXAMINATION; CREATINE KINASE BLOOD LEVEL; CYTOMEGALOVIRUS INFECTION; DERMATOMYOSITIS; DISEASE ACTIVITY; DISEASE COURSE; DISEASE SEVERITY; DRUG DOSE INCREASE; ELECTROMYOGRAPHY; FEMALE; FERRITIN BLOOD LEVEL; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTERSTITIAL LUNG DISEASE; MYALGIA; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PNEUMOCYSTOSIS; PRIORITY JOURNAL; RASH; RECURRENT DISEASE;

ACUTE DISEASE; ADULT; AGED; DEAD-BOX RNA HELICASES; DERMATOMYOSITIS; DRUG MONITORING; FEMALE; FERRITINS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LUNG DISEASES, INTERSTITIAL;

EID: 79960127889     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-010-0371-x     Document Type: Article

References (16)

1. Callen J. Dermatomyositis. Lancet. 2000;355(9197):53-7. (Pubitemid 30072189)
2. Marie I, Hachulla E, Chérin P, Dominique S, Hatron P, Hellot M, et al. Interstitial lung disease in polymyositis and dermatomyositis. Arthritis Rheum. 2002;47(6):614-22. (Pubitemid 35461314)
3. Ito M, Kaise S, Suzuki S, Kazuta Y, Sato Y, Miyata M, et al. Clinico-laboratory characteristics of patients with dermatomyositis accompanied by rapidly progressive interstitial lung disease. Clin Rheumatol. 1999;18(6):462-7. (Pubitemid 30014165)
4. Kameda H, Nagasawa H, Ogawa H, Sekiguchi N, Takei H, Tokuhira M, et al. Combination therapy with corticosteroids, cyclosporin A, and intravenous pulse cyclophosphamide for acute/subacute interstitial pneumonia in patients with dermatomyositis. J Rheumatol. 2005;32(9):1719-26. (Pubitemid 41324810)
5. Gerami P, Schope J, McDonald L, Walling H, Sontheimer R. A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis siné myositis): A missing link within the spectrum of the idiopathic inflammatory myopathies. J Am Acad Dermatol. 2006;54(4):597-613.
6. Sato S, Hirakata M, Kuwana M, Suwa A, Inada S, Mimori T, et al. Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis. Arthritis Rheum. 2005;52(5):1571-6. (Pubitemid 40663949)
7. Sato S, Hoshino K, Satoh T, Fujita T, Kawakami Y, Kuwana M. RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease. Arthritis Rheum. 2009;60(7):2193-200.
8. Nakashima R, Imura Y, Kobayashi S, Yukawa N, Yoshifuji H, Nojima T, et al. The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis- specific autoantigen identified by the anti-CADM- 140 antibody. Rheumatology (Oxford). 2010;49(3):433-40.
9. Fathi M, Vikgren J, Boijsen M, Tylen U, Jorfeldt L, Tornling G, et al. Interstitial lung disease in polymyositis and dermatomyositis: Longitudinal evaluation by pulmonary function and radiology. Arthritis Rheum. 2008;59(5):677-85. (Pubitemid 351679543)
10. Gono T, Kawaguchi Y, Hara M, Masuda I, Katsumata Y, Shinozaki M, et al. Increased ferritin predicts development and severity of acute interstitial lung disease as a complication of dermatomyositis. Rheumatology (Oxford). 2010;49(7):1354-60.
11. Hintze K, Theil E. Cellular regulation and molecular interactions of the ferritins. Cell Mol Life Sci. 2006;63(5):591-600.
12. Tristano A. Macrophage activation syndrome: A frequent but under-diagnosed complication associated with rheumatic diseases. Med Sci Monit. 2008;14(3):RA27-36. (Pubitemid 351457419)
13. Henter J, Horne A, Aricó M, Egeler R, Filipovich A, Imashuku S, et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124-31. (Pubitemid 44958267)
14. Takeuchi O, Akira S. MDA5/RIG-I and virus recognition. Curr Opin Immunol. 2008;20(1):17-22.
15. Christensen M, Pachman L, Schneiderman R, Patel D, Friedman J. Prevalence of Coxsackie B virus antibodies in patients with juvenile dermatomyositis. Arthritis Rheum. 1986;29(11):1365-70. (Pubitemid 17214037)
16. Ward P, Hunninghake G. Lung inflammation and fibrosis. Am J Respir Crit Care Med. 1998;157(4 Pt 2):S123-9. (Pubitemid 28210820)