Risk factors of potentially inappropriate medications among older patients visiting the community health center in rural Taiwan

Archives of Gerontology and Geriatrics

Volumn 53, Issue 2, 2011, Pages 225-228

  Lin, Yung Jie ^a,b   Peng, Li Ning ^a,b   Chen, Liang Kung ^a,b   Lin, Ming Hsien ^a,b   Hwang, Shinn Jang ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Pharmacotherapy of elderly patients; Polypharmacy; Potentially inappropriate medication

Indexed keywords

ALPRAZOLAM; CHLORPHENIRAMINE; CIMETIDINE; CYPROHEPTADINE; DIPHENHYDRAMINE; DIPYRIDAMOLE; DOXAZOSIN; FERROUS SULFATE; INDOMETACIN; NIFEDIPINE; ORPHENADRINE;

ACUTE DISEASE; AGED; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HEALTH CENTER; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICATION ERROR; OUTPATIENT DEPARTMENT; POTENTIALLY INAPPROPRIATE MEDICATION; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; RURAL AREA; TAIWAN;

AGED; AMBULATORY CARE; AMBULATORY CARE FACILITIES; COMMUNITY HEALTH CENTERS; FEMALE; FOLLOW-UP STUDIES; HOSPITALIZATION; HUMANS; MALE; MEDICATION ERRORS; PHYSICIAN'S PRACTICE PATTERNS; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; RURAL POPULATION; TAIWAN;

EID: 79960097149     PISSN: 01674943     EISSN: 18726976     Source Type: Journal    
DOI: 10.1016/j.archger.2010.11.017     Document Type: Article

References (34)

1. Akazawa M., Imai H., Igarashi A., Tsutani K. Potentially inappropriate medication use in elderly Japanese patients. Am. J. Geriatr. Pharmacother. 2010, 8:146-160.
2. Azoulay L., Zargarzadeh A., Salahshouri Z., Oraichi D., Berard A. Inappropriate medication prescribing in community-dwelling elderly people living in Iran. Eur. J. Clin. Pharmacol. 2005, 61:913-919.
3. Beers M.H. Explicit criteria for determining potentially inappropriate medication use by the elderly. Arch. Intern. Med. 1997, 157:1531-1536.
4. Beers M.H., Ouslander J.G., Rollingher I., Reuben D.B., Brooks J., Beck J.C. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch. Intern. Med. 1991, 151:1825-1832.
5. Carlson, G., 2008. What's the difference between a chronic illness and an acute illness? Available from: (accessed 26.07.10). http://missourifamilies.org/quick/healthqa/healthqa15.htm.
6. Chan D.C., Hao Y.T., Wu S.C. Polypharmacy among disabled Taiwanese elderly: a longitudinal observational study. Drugs Aging 2009, 26:345-354.
7. Chang C.M., Liu P.Y., Yang Y.H., Yang Y.C., Wu C.F., Lu F.H. Potentially inappropriate drug prescribing among first-visit elderly outpatients in Taiwan. Pharmacotherapy 2004, 24:848-855.
8. Chang C.M., Liu P.Y., Yang Y.H., Yang Y.C., Wu C.F., Lu F.H. Use of the Beers criteria to predict adverse drug reactions among first-visit elderly outpatients. Pharmacotherapy 2005, 25:831-838.
9. Chen C.Y. Meeting the challenges of eldercare in Taiwan's aging society. J. Clin. Gerontol. Geriatr. 2010, 1:2-4.
10. Chen L.K. A new era of research on clinical gerontology and geriatrics in Asia. J. Clin. Gerontol. Geriatr. 2010, 1:1.
11. Chen L.K., Peng L.N., Lin M.H., Lai H.Y., Hwang S.J., Chiou S.T. Predicting new onset diabetes mellitus by metabolic syndrome among older adults in rural Taiwan. J. Atheroscler. Thromb. 2009, 16:627-632.
12. Chen Y.C., Hwang S.J., Lai H.Y., Chen T.J., Lin M.H., Chen L.K., Lee C.H. Potentially inappropriate medication for emergency department visits by elderly patients in Taiwan. Pharmacoepidemiol. Drug Saf. 2009, 18:53-61.
13. De Oliveira Martins S., Soares M.A., Foppe van Mil J.W., Cabrita J. Inappropriate drug use by Portuguese elderly outpatients: effect of the Beers criteria update. Pharm. World Sci. 2006, 28:296-301.
14. Donabedian A. The quality of care. How can it be assessed?. J. Am. Med. Assoc. 1988, 260:1743-1748.
15. Fialova D., Topinkova E., Gambassi G. Potentially inappropriate medication use among elderly home care patients in Europe. J. Am. Med. Assoc. 2005, 293:1348-1358.
16. Fick D.M., Cooper J.W., Wade W.E., Waller J.L., Maclean J.R., Beers M.H. Updating the Beers criteria for potentially inappropriate medication use in older adults. Arch. Intern. Med. 2003, 163:2716-2724.
17. Gavilan Moral E., Morales Suarez-Varela M.T., Hoyos Esteban J.A., Perez Suanes A.M. Inappropriate multiple medication and prescribing of drugs immobile elderly patients living in the community. Aten. Primaria 2006, 38:476-480.
18. Juang S.J., Peng L.N., Lin M.H., Lai H.Y., Hwang S.J., Chen L.K., Chiou S.T. Metabolic characteristics of Chinese breakfast vegetarian elderly people in rural Taiwan. Arch. Gerontol. Geriatr. 2010, 50:20-23.
19. Lai H.Y., Hwang S.J., Chen Y.C., Chen T.J., Lin M.H., Chen L.K. Prevalence of the prescribing of potentially inappropriate medications at ambulatory care visits by elderly patients covered by the Taiwanese National Health Insurance program. Clin. Ther. 2009, 31:1859-1870.
20. Lin H.Y., Liao C.C., Cheng S.H., Wang P.C., Hsueh Y.S. Association of potentially inappropriate medication use with adverse outcomes in ambulatory elderly patients with chronic diseases: experience in a Taiwanese medical setting. Drugs Aging 2008, 25:49-59.
21. Lin M.H., Chou M.Y., Liang C.K., Peng L.N., Chen L.K. Population aging and its impact: strategies of health-care system in Taipei. Aging Res. Rev. 2010, 9S:S23-S27.
22. Lindley C.M., Tully M.P., Paramsothy V., Tallis R.C. Inappropriate medication is a major cause of adverse drug reactions in elderly patients. Age Ageing 1992, 21:294-300.
23. Liu L.K., Peng L.N., Chen L.K., Hwang S.J., Chiou S.T. Prehypertension among middle-aged and elderly people in Taiwan: a five-year follow-up. J. Atheroscler. Thromb. 2010, 17:189-194.
24. Maio V., Yuen E.J., Novielli K., Smith K.D., Louis D.Z. Potentially inappropriate medication prescribing for elderly outpatients in Emilia Romagna, Italy: a population-based cohort study. Drugs Aging 2006, 23:915-924.
25. Onder G., Landi F., Cesari M., Gambassi G., Carbonin P., Bernabei R. Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly. Eur. J. Clin. Pharmacol. 2003, 59:157-162.
26. Onder G., Landi F., Liperoti R., Fialova D., Gambassi G., Bernabei R. Impact of inappropriate drug use among hospitalized older adults. Eur. J. Clin. Pharmacol. 2005, 61:453-459.
27. Saab Y.B., Hachem A., Sinno S., El-Moalem H. Inappropriate medication use in elderly Lebanese outpatients: prevalence and risk factors. Drugs Aging 2006, 23:743-752.
28. Spinewine A., Schmader K.E., Barber N., Hughes C., Lapane K.L., Swine C., Hanlon T.J. Appropriate prescribing in elderly people: how well can it be measured and optimised?. Lancet 2007, 370:173-184.
29. The Statistical Annual Report of Medical Care Institutions Status & Hospitals Utilization, April 2010. Department of Health, Executive Yuan, Taiwan, ROC.
30. Turnheim K. When drug therapy gets old: pharmacokinetics and pharma-codynamics in the elderly. Exp. Gerontol. 2003, 38:843-853.
31. Wawruch M., Fialova D., Zikavska M., Wsolova L., Jezova D., Kuzelova M., Liskova S., Krajcik S. Factors influencing the use of potentially inappropriate medication in older patients in Slovakia. J. Clin. Pharm. Ther. 2008, 33:381-392.
32. Willcox S.M., Himmelstein D.U., Woolhandler S. Inappropriate drug prescribing for the community-dwelling elderly. J. Am. Med. Assoc. 1994, 272:292-296.
33. World Health Organization, 1992. ICD - 9th International Statistical Classification of Diseases and Related Health Problems, ninth ed. WHO, Geneva.
34. Zhan C., Sangl J., Bierman A.S., Miller M.R., Friedman B., Wickizer S.W., Meyer G.S. Potentially inappropriate medication use in the community dwelling elderly. J. Am. Med. Assoc. 2001, 286:2823-2829.