Helical tomotherapy vs. Intensity-modulated proton therapy for whole pelvis irradiation in high-risk prostate cancer patients: Dosimetric, normal tissue complication probability, and generalized equivalent uniform dose analysis

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 5, 2011, Pages 1589-1600

  Widesott, Lamberto ^a   Pierelli, Alessio ^b   Fiorino, Claudio ^b   Lomax, Antony J ^c   Amichetti, Maurizio ^a   Cozzarini, Cesare ^b   Soukup, Martin ^d   Schneider, Ralf ^c   Hug, Eugen ^c   Di Muzio, Nadia ^b   Calandrino, Riccardo ^b   Schwarz, Marco ^a  

^a ATreP Agenzia Provinciale per la Protonterapia   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c PAUL SCHERRER INSTITUTE   (Switzerland)

^d UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Intensity modulated proton therapy; Normal tissue complication probability; Pelvic lymph nodes; Prostate; Tomotherapy

Indexed keywords

NORMAL TISSUE COMPLICATION PROBABILITIES; PELVIC LYMPH NODES; PROSTATE; PROTON THERAPY; TOMOTHERAPY;

BODY FLUIDS; DISEASES; DOSIMETERS; DOSIMETRY; OPTIMIZATION; PROBABILITY; PROTON BEAMS; PROTONS; TISSUE;

PATIENT TREATMENT;

ADULT; ARTICLE; BLADDER INJURY; BONE INJURY; CANCER RADIOTHERAPY; CANCER RISK; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DOSIMETRY; GASTROINTESTINAL TOXICITY; HUMAN; INTENSITY MODULATED PROTON THERAPY; INTENSITY MODULATED RADIATION THERAPY; INTESTINE INJURY; MALE; PELVIS LYMPH NODE; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RADIATION INJURY; RECTUM HEMORRHAGE; RECTUM INJURY; TOMOTHERAPY; TREATMENT PLANNING;

DOSE FRACTIONATION; HUMANS; LYMPH NODES; LYMPHATIC IRRADIATION; MALE; ORGANS AT RISK; PELVIS; PENIS; PHOTONS; PROSTATE; PROSTATIC NEOPLASMS; PROTONS; RADIATION INJURIES; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED; RECTUM; RELATIVE BIOLOGICAL EFFECTIVENESS; SEMINAL VESICLES;

EID: 79960088753     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.10.005     Document Type: Article

References (31)

1. C.A. Lawton, M. DeSilvio, and M. Roach An update of the phase III trial comparing whole pelvic to prostate only radiotherapy and neoadjuvant to adjuvant total androgen suppression: Updated analysis of RTOG 94-13, with emphasis on unexpected hormone/radiation interactions Int J Radiat Oncol Biol Phys 69 2007 646 655 (Pubitemid 47418390)
2. P. Pommier, S. Chabaud, and J.L. Lagrange Is there a role for pelvic irradiation in localized prostate adenocarcinoma? Preliminary results of GETUG-01 J Clin Oncol 25 2007 5366 5373 (Pubitemid 350232211)
3. P.L. Nguyen, and A.V. D'Amico Targeting pelvic lymph nodes in men with intermediate- and high-risk prostate cancer despite two negative randomized trials J Clin Oncol 26 2008 2055 2056
4. G. Rodrigues, S. Yartsev, and J. Chen A comparison of prostate IMRT and helical tomotherapy class solutions Radiother Oncol 80 2006 374 377 (Pubitemid 44419428)
5. J.D. Slater, C.J. Rossi, and L.T. Yonemoto Proton therapy for prostate cancer: The initial Loma Linda University experience Int J Radiat Oncol Biol Phys 59 2004 348 352 (Pubitemid 38622585)
6. A. Trofimov, P.L. Nguyen, and J.J. Coen Radiotherapy treatment of early-stage prostate cancer with IMRT and protons: A treatment planning comparison Int J Radiat Oncol Biol Phys 69 2007 444 453 (Pubitemid 47380086)
7. U. Schneider, A. Lomax, and P. Pemler The impact of IMRT and proton radiotherapy on secondary cancer incidence Strahlenther Onkol 182 2006 647 652 (Pubitemid 44657651)
8. J.F. Fowler The radiobiology of prostate cancer including new aspects of fractionatedradiotherapy Acta Oncol 44 2005 265 276 (Pubitemid 40904130)
9. C. Fiorino, G. Fellin, and T. Rancati Clinical and dosimetric predictors of late rectal syndrome after 3D-CRT for localized prostate cancer: Preliminary results of a multicenter prospective study Int J Radiat Oncol Biol Phys 70 2008 1130 1137 (Pubitemid 351296107)
10. T.R. Mackie History of tomotherapy Phys Med Biol 51 2006 R427 R453
11. M. Soukup, M. Fippel, and M. Alber A pencil beam algorithm for intensity modulated proton therapy derived from Monte Carlo simulations Phys Med Biol 50 2005 5089 5104 (Pubitemid 41503992)
12. J.T. Lyman Complication probabilities as assessed from dose-volume histograms Radiat Res 104 1985 13 19
13. Q. Wu, R. Mohan, and A. Niemierko Optimization of intensity-modulated radiotherapy plans based on the equivalent uniform dose Int J Radiat Oncol Biol Phys 52 2002 224 235 (Pubitemid 34041575)
14. Gianolini, S, Henggeler D. www.vodca.ch. Accessed February 2009.
15. B. Sanchez-Nieto, and A.E. Nahum BIOPLAN: Software for the biological evaluation of radiotherapy treatment plans Med Dosim 25 2000 71 76 (Pubitemid 30336646)
16. C. Fiorino, S. Gianolini, and A.E. Nahum A cylindrical model of the rectum: Comparing dose-volume, dose-surface and dose-wall histograms in the radiotherapy of prostate cancer Phys Med Biol 48 2003 2603 2616 (Pubitemid 37069370)
17. S.T.H. Peeters, M.S. Hoogeman, and W.D. Heemsbergen Rectal bleeding, fecal incontinence, and high stool frequency after conformal radiotherapy for prostate cancer: Normal tissue complication probability modeling Int J Radiat Oncol Biol Phys 66 2006 11 19 (Pubitemid 44175644)
18. S.L. Tucker, L. Dong, and W.R. Bosch Fit of a generalized Lyman normal-tissue complication probability (NTCP) model to grade >2 late rectal toxicity data from patient treated on protocol RTOG 94-06 Int J Radiat Oncol Biol Phys 69 2007 S8
19. M. Sohn, D. Yan, and J. Liang Incidence of late rectal bleeding in high-dose conformal radiotherapy of prostate cancer using equivalent uniform dose-based and dose-volume-based normal tissue complication probability models Int J Radiat Oncol Biol Phys 67 2007 1066 1073
20. T. Rancati, C. Fiorino, and V. Vavassori Late rectal bleeding after conformal radiotherapy for prostate cancer: NTCP modeling Radiother Oncol 88 2008 S332 S333
21. M. Roach, M. DeSilvio, and R. Valicenti Whole-pelvis, "mini-pelvis," or prostate-only external beam radiotherapy after neoadjuvant and concurrent hormonal therapy in patients treated in the Radiation Therapy Oncology Group 9413 trial Int J Radiat Oncol Biol Phys 66 2006 647 653 (Pubitemid 44436716)
22. J.B. Ashman, M.J. Zelefsky, and M.S. Hunt Whole pelvic radiotherapy for prostate cancer using 3D conformal and intensity-modulated radiotherapy Int J Radiat Oncol Biol Phys 63 2005 765 771 (Pubitemid 41400064)
23. C. Cozzarini, C. Fiorino, and N. Di Muzio Significant reduction of acute toxicity following pelvic irradiation with helical tomotherapy in patients with localized prostate cancer Radiother Oncol 84 2007 164 170 (Pubitemid 47299141)
24. C. Fiorino, R. Valdagni, and T. Rancati Dose-volume effects for normal tissues in external radiotherapy: Pelvis Radiother Oncol 93 2009 153 167
25. A.N. Solan, J.A. Cesaretti, and N.N. Stone There is no correlation between erectile dysfunction and dose to penile bulb and neurovascular bundles following real-time low-dose-rate prostate brachytherapy Int J Radiat Oncol Biol Phys 73 2009 1468 1474
26. M.W. Brown, J.P. Brooks, and P.S. Albert An analysis of erectile function after intensity modulated radiation therapy for localized prostate carcinoma Prostate Cancer Prostatic Dis 10 2007 189 193 (Pubitemid 46881671)
27. J.D. Fontenot, A.K. Lee, and W.D. Newhauser Risk of secondary malignant neoplasms from proton therapy and intensity-modulated x-ray therapy for early-stage prostate cancer Int J Radiat Oncol Biol Phys 74 2009 616 622
28. M. Tubiana Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review Radiother Oncol 91 2009 4 15
29. A.J. Lomax Intensity modulated proton therapy and its sensitivity to treatment uncertainties 1: The potential effects of calculational uncertainties Phys Med Biol 53 2008 1027 1042 (Pubitemid 351238121)
30. P. Andreo On the clinical spatial resolution achievable with protons and heavier charged particle radiotherapy beams Phys Med Biol 54 2009 N205 N215
31. J. Unkelbach, T. Bortfeld, and B.C. Martin Reducing the sensitivity of IMPT treatment plans to setup errors and range uncertainties via probabilistic treatment planning Med Phys 36 2009 149 163