Development of a method for the determination of glycine in human cerebrospinal fluid using pre-column derivatization and LC-MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 2, 2011, Pages 315-323

  Wilson, Sarah F ^a   James, Christopher A ^a   Zhu, Xiaochun ^a   Davis, Mike T ^a   Rose, Mark J ^a  

^a AMGEN INC   (United States)

Author keywords

Biomarker; Cerebrospinal fluid; Glycine; LC MS MS; PITC

Indexed keywords

GLYCINE; PHENYL ISOTHIOCYANATE;

AMINO ACID ANALYSIS; ARTICLE; CALIBRATION; CEREBROSPINAL FLUID; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DERIVATIZATION; HUMAN; LIMIT OF QUANTITATION; PRIORITY JOURNAL; QUALITY CONTROL; REVERSED PHASE LIQUID CHROMATOGRAPHY; ROOM TEMPERATURE; STANDARD; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY;

BIOLOGICAL MARKERS; CALIBRATION; CHROMATOGRAPHY, LIQUID; COLD TEMPERATURE; FREEZING; GLYCINE; HUMANS; ISOTHIOCYANATES; MOLECULAR STRUCTURE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 79960033252     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.05.009     Document Type: Article

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