Antisense oligonucleotide therapy for TTR amyloidosis

Amyloid

Volumn 18, Issue SUPPL. 1, 2011, Pages 60-

  Benson, M D ^a,b   Pandey, S ^c   Witchell, D ^c   Jazayeri, A ^c   Siwkowski, A ^c   Monia, B ^c   Kluve Beckerman, B ^a  

^a INDIANA UNIVERSITY   (United States)

^b RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PREALBUMIN; AMYLOID; CONGO RED; GUANIDINE; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; PARAFFIN; XYLENE; 2 CHLORODEOXYADENOSINE TRIPHOSPHATE; BORTEZOMIB; BRAIN NATRIURETIC PEPTIDE; CLADRIBINE; CORTICOSTEROID;

AMYLOIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTISENSE THERAPY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; LIVER FUNCTION TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; AGED; AMINO ACID SEQUENCE; BONE MARROW BIOPSY; CASE REPORT; CENTRAL NERVOUS SYSTEM; COGNITIVE DEFECT; FEMALE; HUMAN; HUMAN TISSUE; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; LATERAL BRAIN VENTRICLE; LEFT HEMISPHERE; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN ELECTROPHORESIS; SEQUENCE ANALYSIS; STEREOTACTIC BIOPSY; TREMOR; BLOOD SMEAR; BRONCHIOLITIS OBLITERANS; CANCER CHEMOTHERAPY; CANCER SURGERY; CONGESTIVE HEART FAILURE; CORTICOSTEROID THERAPY; DRUG MEGADOSE; ECCHYMOSIS; HAIRY CELL LEUKEMIA; HISTOPATHOLOGY; LYMPHADENOPATHY; MACROGLOSSIA; MALE; MULTIPLE CYCLE TREATMENT; MULTIPLE MYELOMA; PNEUMONIA; SPLENECTOMY; TREATMENT RESPONSE; WEIGHT REDUCTION;

EID: 79960024416     PISSN: 13506129     EISSN: 17442818     Source Type: Journal    
DOI: 10.3109/13506129.2011.574354     Document Type: Article

References (2)

1. Benson MD, Kluve-Beckerman B, Zeldenrust SR, Siesky AM, Bodenmiller DM, Showalter AD, Sloop KW. Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides. Muscle Nerve 2006;33:609-618.
2. Liepnieks JJ, Benson MD. Progression of cardiac amyloid deposition in hereditary transthyretin amyloidosis patients after liver transplantation. Amyloid 2007;14:277-282. (Pubitemid 350035574)