메뉴 건너뛰기




Volumn 5, Issue 2, 2011, Pages 126-135

Anti-IL-1 β therapies

Author keywords

Antibody; IL 1 ; IL 1 receptor antagonists; IL 1 trap; Inflammasome; Inflammatory disease

Indexed keywords

ADAPTOR PROTEIN; CANAKINUMAB; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CRYOPYRIN; CYT013 IL1BQB; CYTOKINE RECEPTOR ANTAGONIST; GEVOKIZUMAB; IMMUNOLOGIC AGENT; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT INTRACELLULAR ISOFORM; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT SECRETED ISOFORM; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA ANTIBODY; MEVALONATE KINASE; PATTERN RECOGNITION RECEPTOR; PLACEBO; PROTEIN; PROTEIN CARD8; PYRIN; RANIBIZUMAB; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; TALMAPIMOD; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; VALSARTAN;

EID: 79960023037     PISSN: 18722156     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221511796392024     Document Type: Article
Times cited : (22)

References (77)
  • 3
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010; 140: 821-32.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 4
    • 0036839577 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors: Implications for regulating inflammatory and immune responses
    • Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol 2002; 23: 509-12.
    • (2002) Trends Immunol , vol.23 , pp. 509-512
    • Beg, A.A.1
  • 5
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 2002; 296: 301-5.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 6
    • 66449088641 scopus 로고    scopus 로고
    • Pathogen recognition and inflammatory signaling in innate immune defenses
    • Mogensen TH. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev 2009; 22: 240-73.
    • (2009) Clin Microbiol Rev , vol.22 , pp. 240-273
    • Mogensen, T.H.1
  • 7
    • 79953061608 scopus 로고    scopus 로고
    • Human TLRs and IL-1Rs in host defense: Natural insights from evolutionary, epidemiological, and clinical genetics
    • Casanova JL, Abel L, Quintana-Murci L. Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics. Annu Rev Immunol 2011; 29: 447-91.
    • (2011) Annu Rev Immunol , vol.29 , pp. 447-491
    • Casanova, J.L.1    Abel, L.2    Quintana-Murci, L.3
  • 8
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama MM, Kikuchi T, Natsukawa N, et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004; 5: 730-7.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.M.1    Kikuchi, T.2    Natsukawa, N.3
  • 9
    • 35348932070 scopus 로고    scopus 로고
    • Intracellular NOD-like receptors in host defense and disease
    • Kanneganti TD, Lamkanfi M, Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity 2007; 27: 549-59.
    • (2007) Immunity , vol.27 , pp. 549-559
    • Kanneganti, T.D.1    Lamkanfi, M.2    Nunez, G.3
  • 10
    • 34547143110 scopus 로고    scopus 로고
    • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
    • Takaoka AZ, Wang MK, Choi H, et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007; 448: 501-5.
    • (2007) Nature , vol.448 , pp. 501-505
    • Takaoka, A.Z.1    Wang, M.K.2    Choi, H.3
  • 11
    • 63649133278 scopus 로고    scopus 로고
    • AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
    • Hornung VA, Ablasser M, Charrel-Dennis F, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009; 458: 514-8.
    • (2009) Nature , vol.458 , pp. 514-518
    • Hornung, V.A.1    Ablasser, M.2    Charrel-Dennis, F.3
  • 12
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira SS, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.S.1    Takeuchi, O.2
  • 13
    • 38149113537 scopus 로고    scopus 로고
    • NLR proteins: Integral members of innate immunity and mediators of inflammatory diseases
    • Wilmanski JM, Petnicki-Ocwieja T, Kobayashi KS. NLR proteins: integral members of innate immunity and mediators of inflammatory diseases. J Leukoc Biol 2008; 83: 13-30.
    • (2008) J Leukoc Biol , vol.83 , pp. 13-30
    • Wilmanski, J.M.1    Petnicki-Ocwieja, T.2    Kobayashi, K.S.3
  • 14
    • 35348932070 scopus 로고    scopus 로고
    • Intracellular NOD-like receptors in host defense and disease
    • Kanneganti TD, Lamkanfi M, Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity 2007; 27: 549-59.
    • (2007) Immunity , vol.27 , pp. 549-559
    • Kanneganti, T.D.1    Lamkanfi, M.2    Nunez, G.3
  • 17
    • 0036584144 scopus 로고    scopus 로고
    • NDPP1 is a novel CARD domain containing protein which can inhibit apoptosis and suppress NF-kappaB activation
    • Zhang H, Fu W. NDPP1 is a novel CARD domain containing protein which can inhibit apoptosis and suppress NF-kappaB activation. Int J Oncol 2002; 20: 1035-40.
    • (2002) Int J Oncol , vol.20 , pp. 1035-1040
    • Zhang, H.1    Fu, W.2
  • 18
    • 0035941220 scopus 로고    scopus 로고
    • CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NFkappa B activation pathways
    • Bouchier-Hayes L, Conroy H, Egan H, et al. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NFkappa B activation pathways. J Biol Chem 2001; 276: 44069-77.
    • (2001) J Biol Chem , vol.276 , pp. 44069-44077
    • Bouchier-Hayes, L.1    Conroy, H.2    Egan, H.3
  • 19
    • 0035943736 scopus 로고    scopus 로고
    • TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer
    • Pathan N, Marusawa H, Krajewska M, et al. TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. J Biol Chem 2001; 276: 32220-9.
    • (2001) J Biol Chem , vol.276 , pp. 32220-32229
    • Pathan, N.1    Marusawa, H.2    Krajewska, M.3
  • 20
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1b processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder
    • Agostini F, Martinon K, Burns EM, et al. NALP3 forms an IL-1b processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder. Immunity 2004; 20: 319-25.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, F.1    Martinon, K.2    Burns, E.M.3
  • 21
    • 0037134457 scopus 로고    scopus 로고
    • CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
    • Razmara M, Srinivasula SM, Wang L, et al. CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis. J Biol Chem 2002; 277: 13952-8.
    • (2002) J Biol Chem , vol.277 , pp. 13952-13958
    • Razmara, M.1    Srinivasula, S.M.2    Wang, L.3
  • 22
    • 77953733399 scopus 로고    scopus 로고
    • Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling
    • von Kampen O, Lipinski S, Till A, et al. Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling. J Biol Chem 2010; 285: 19921-6.
    • (2010) J Biol Chem , vol.285 , pp. 19921-19926
    • von Kampen, O.1    Lipinski, S.2    Till, A.3
  • 23
    • 0033528272 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn's disease
    • Schreiber S, Nikolaus S, Hampe J, et al. Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn's disease. Lancet 1999; 353: 459-61.
    • (1999) Lancet , vol.353 , pp. 459-461
    • Schreiber, S.1    Nikolaus, S.2    Hampe, J.3
  • 24
    • 79953228503 scopus 로고    scopus 로고
    • Association of Card8 with inflammatory bowel disease in Koreans
    • Yang SK, Kim H, Hong M, et al. Association of Card8 with inflammatory bowel disease in Koreans. J Hum Genet 2011; 56: 217-23.
    • (2011) J Hum Genet , vol.56 , pp. 217-223
    • Yang, S.K.1    Kim, H.2    Hong, M.3
  • 26
    • 43049177426 scopus 로고    scopus 로고
    • Deficiency of the NF-kappaB inhibitor caspase activating recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity
    • Fontalba A, Martinez-Taboada V, Gutierrez O, et al. Deficiency of the NF-kappaB inhibitor caspase activating recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity. J Immunol 2007; 179: 4867-73.
    • (2007) J Immunol , vol.179 , pp. 4867-4873
    • Fontalba, A.1    Martinez-Taboada, V.2    Gutierrez, O.3
  • 27
    • 66949174089 scopus 로고    scopus 로고
    • Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men
    • Schoultz I, Verma D, Halfvarsson J, et al. Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. Am J Gastroenterol 2009; 104(5): 1180-8.
    • (2009) Am J Gastroenterol , vol.104 , Issue.5 , pp. 1180-1188
    • Schoultz, I.1    Verma, D.2    Halfvarsson, J.3
  • 28
    • 77950304735 scopus 로고    scopus 로고
    • CARD8 p. C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis
    • Kastbom A, Johansson M, Verma D, Söderkvist P, Rantapää-Dahlqvist S. CARD8 p. C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis. Ann Rheum Dis 2010; 69: 723-6.
    • (2010) Ann Rheum Dis , vol.69 , pp. 723-726
    • Kastbom, A.1    Johansson, M.2    Verma, D.3    Söderkvist, P.4    Rantapää-Dahlqvist, S.5
  • 29
    • 54749096427 scopus 로고    scopus 로고
    • Deficiency of CARD8 is associated with increased Alzheimer's disease risk in women
    • Fontalba A, Gutiérrez O, Llorca J, Mateo IJ. Deficiency of CARD8 is associated with increased Alzheimer's disease risk in women. Dement Geriatr Cogn Disord 2008; 26: 247-50.
    • (2008) Dement Geriatr Cogn Disord , vol.26 , pp. 247-250
    • Fontalba, A.1    Gutiérrez, O.2    Llorca, J.3    Mateo, I.J.4
  • 30
    • 67650459139 scopus 로고    scopus 로고
    • Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk
    • Fontalba A, Gutiérrez O, Llorca J. Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk. J Neurol 2009; 256: 1184-6.
    • (2009) J Neurol , vol.256 , pp. 1184-1186
    • Fontalba, A.1    Gutiérrez, O.2    Llorca, J.3
  • 31
    • 34548653262 scopus 로고    scopus 로고
    • Recent progress in elucidating the structure, function and evolution of disease resistance genes in plants
    • Liu J, Liu X, Dai L, Wang G. Recent progress in elucidating the structure, function and evolution of disease resistance genes in plants. J Genet Genomics 2007; 34: 765-76.
    • (2007) J Genet Genomics , vol.34 , pp. 765-776
    • Liu, J.1    Liu, X.2    Dai, L.3    Wang, G.4
  • 32
    • 47249089097 scopus 로고    scopus 로고
    • IL-1, IL-18, and IL-33 families of cytokines
    • Arend WP, Palmer G, Gabay C. IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 2008; 223: 20-38.
    • (2008) Immunol Rev , vol.223 , pp. 20-38
    • Arend, W.P.1    Palmer, G.2    Gabay, C.3
  • 33
    • 0026710899 scopus 로고
    • The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci
    • Steinkasserer A, Spurr NK, Cox S, Jeggo P, Sim RB. The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci. Genomics 1992; 13: 654-7.
    • (1992) Genomics , vol.13 , pp. 654-657
    • Steinkasserer, A.1    Spurr, N.K.2    Cox, S.3    Jeggo, P.4    Sim, R.B.5
  • 34
    • 0027477308 scopus 로고
    • The human interleukin-1 receptor antagonist (IL1RN) gene is located in the chromosome 2q14 region
    • Patterson D, Jones C, Hart I, et al. The human interleukin-1 receptor antagonist (IL1RN) gene is located in the chromosome 2q14 region. Genomics 1993; 15: 173-6.
    • (1993) Genomics , vol.15 , pp. 173-176
    • Patterson, D.1    Jones, C.2    Hart, I.3
  • 35
    • 0028675659 scopus 로고
    • The interleukin-1 family: 10 years of discovery
    • Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J 1994; 8: 1314-25.
    • (1994) FASEB J , vol.8 , pp. 1314-1325
    • Dinarello, C.A.1
  • 37
    • 0035179970 scopus 로고    scopus 로고
    • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
    • Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001; 29: 301-5.
    • (2001) Nat Genet , vol.29 , pp. 301-305
    • Hoffman, H.M.1    Mueller, J.L.2    Broide, D.H.3    Wanderer, A.A.4    Kolodner, R.D.5
  • 38
    • 17844391059 scopus 로고    scopus 로고
    • Molecular and genetic characteristics of hereditary autoinflammatory diseases
    • Tunca M, Ozdogan H. Molecular and genetic characteristics of hereditary autoinflammatory diseases. Curr Drug Targets Inflamm Allergy 2005; 4: 77-80.
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 77-80
    • Tunca, M.1    Ozdogan, H.2
  • 39
    • 79959235786 scopus 로고    scopus 로고
    • Familial mediterranean fever-A review
    • Feb 23
    • Shohat M, Halpern GJ. Familial mediterranean fever-A review. Genet Med 2011 Feb 23.
    • (2011) Genet Med
    • Shohat, M.1    Halpern, G.J.2
  • 40
    • 0032854744 scopus 로고    scopus 로고
    • Identification and characterization of three novel missense mutations in mevalonate kinase cDNA causing mevalonic aciduria, a disorder of isoprene biosynthesis
    • Houten SM, Romeijn GJ, Koster J, et al. Identification and characterization of three novel missense mutations in mevalonate kinase cDNA causing mevalonic aciduria, a disorder of isoprene biosynthesis. Hum Mol Genet 1999; 8: 1523-8.
    • (1999) Hum Mol Genet , vol.8 , pp. 1523-1528
    • Houten, S.M.1    Romeijn, G.J.2    Koster, J.3
  • 41
    • 0032987982 scopus 로고    scopus 로고
    • Poll-The BT. Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome
    • Houten SM, Kuis W, Duran M, et al. Poll-The BT. Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome. Nat Genet 1999; 22: 175-7.
    • (1999) Nat Genet , vol.22 , pp. 175-177
    • Houten, S.M.1    Kuis, W.2    Duran, M.3
  • 42
    • 66649121678 scopus 로고    scopus 로고
    • An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
    • Aksentijevich I, Masters SL, Ferguson PJ, et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 2009; 360(23): 2426-37.
    • (2009) N Engl J Med , vol.360 , Issue.23 , pp. 2426-2437
    • Aksentijevich, I.1    Masters, S.L.2    Ferguson, P.J.3
  • 43
    • 77957688721 scopus 로고    scopus 로고
    • Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study
    • So A, De Meulemeester M, Pikhlak A, et al. Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study. Arthritis Rheum 2010; 62: 3064-76.
    • (2010) Arthritis Rheum , vol.62 , pp. 3064-3076
    • So, A.1    de Meulemeester, M.2    Pikhlak, A.3
  • 44
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • Zhou R, Tardivel A, Thorens B, et al. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2010; 11: 136-40.
    • (2010) Nat Immunol , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3
  • 45
    • 65649140025 scopus 로고    scopus 로고
    • Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
    • Gasse P, Riteau N, Charron S, et al. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med 2009, 179: 903-13.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 903-913
    • Gasse, P.1    Riteau, N.2    Charron, S.3
  • 46
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C, Petrilli V, Van Bruggen R, et al.: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008; 320: 674-7.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    van Bruggen, R.3
  • 47
    • 77955630849 scopus 로고    scopus 로고
    • Blocking IL-1beta to slow down progression of ALS?
    • van der Meer JW, Simon A. Blocking IL-1beta to slow down progression of ALS? Proc Natl Acad Sci USA 2010; 107: 12741-2.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 12741-12742
    • van der Meer, J.W.1    Simon, A.2
  • 48
    • 77955649302 scopus 로고    scopus 로고
    • Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis
    • Meissner F, Molawi K, Zychlinsky A. Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis. Proc Natl Acad Sci USA 2010; 107: 13046-50.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13046-13050
    • Meissner, F.1    Molawi, K.2    Zychlinsky, A.3
  • 49
    • 0035497740 scopus 로고    scopus 로고
    • Neutralization of interleukin-1beta in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling
    • Hwang MW, Matsumori A, Furukawa Y, et al. Neutralization of interleukin-1beta in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling. J Am Coll Cardiol 2001; 38: 1546-53.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1546-1553
    • Hwang, M.W.1    Matsumori, A.2    Furukawa, Y.3
  • 50
    • 0035159542 scopus 로고    scopus 로고
    • The role of inflammation in the anaemia of end-stage renal disease
    • Stenvinkel P. The role of inflammation in the anaemia of end-stage renal disease. Nephrol Dial Transplant 2001; 16: 36-40.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 36-40
    • Stenvinkel, P.1
  • 51
    • 70350780280 scopus 로고    scopus 로고
    • Dysfunctional inflammasome in Schnitzler's syndrome
    • Pizzirani C, Falzoni S, Govoni M, et al. Dysfunctional inflammasome in Schnitzler's syndrome. Rheumatology (Oxford) 2009; 48: 1304-8.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 1304-1308
    • Pizzirani, C.1    Falzoni, S.2    Govoni, M.3
  • 69
    • 76149128376 scopus 로고    scopus 로고
    • Periodic fever syndromes pediatrics in review
    • Goldsmith DP. Periodic fever syndromes pediatrics in review. Pediatrics Rev 2009; 30: e34-e41.
    • (2009) Pediatrics Rev , vol.30
    • Goldsmith, D.P.1
  • 70
    • 34247170807 scopus 로고    scopus 로고
    • Interleukin-1-receptor antagonist in type 2 diabetes mellitus
    • Larsen CM, Faulenbach M, Vaag A, et al. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 2007; 356: 1517-26.
    • (2007) N Engl J Med , vol.356 , pp. 1517-1526
    • Larsen, C.M.1    Faulenbach, M.2    Vaag, A.3
  • 71
    • 61449122079 scopus 로고    scopus 로고
    • Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1β-induced interleukin 6 production and the myeloma proliferative component
    • Lust JA, Lacy MQ, Zeldenrust SR, et al. Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1β-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin Proc 2009; 84: 114-22.
    • (2009) Mayo Clin Proc , vol.84 , pp. 114-122
    • Lust, J.A.1    Lacy, M.Q.2    Zeldenrust, S.R.3
  • 72
    • 77951665667 scopus 로고    scopus 로고
    • VCU-ART investigators. Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction
    • Abbate A, Kontos MC, Grizzard JD, et al. VCU-ART investigators. Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction. Am J Cardiol 2010; 105: 1371-7.
    • (2010) Am J Cardiol , vol.105 , pp. 1371-1377
    • Abbate, A.1    Kontos, M.C.2    Grizzard, J.D.3
  • 73
    • 62549104691 scopus 로고    scopus 로고
    • Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study
    • Chevalier X, Goupille P, Beaulieu AD, et al. Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2009; 61: 344-52.
    • (2009) Arthritis Rheum , vol.61 , pp. 344-352
    • Chevalier, X.1    Goupille, P.2    Beaulieu, A.D.3
  • 74
    • 49449094179 scopus 로고    scopus 로고
    • Efficacy and safety of rilonacept (interleukin-1 TRAP) in patients with cryopyrinassociated periodic syndromes: Results from two sequential placebocontrolled studies
    • Hoffman HM, Throne ML, Amar NJ, et al. Efficacy and safety of rilonacept (interleukin-1 TRAP) in patients with cryopyrinassociated periodic syndromes: results from two sequential placebocontrolled studies. Arthritis Rheum 2008, 58: 2443-52.
    • (2008) Arthritis Rheum , vol.58 , pp. 2443-2452
    • Hoffman, H.M.1    Throne, M.L.2    Amar, N.J.3
  • 75
    • 66649102432 scopus 로고    scopus 로고
    • Use of canakinumab in the cryopyrin-associated periodic syndrome
    • Canakinumab in CAPS study group
    • Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB, et al. Canakinumab in CAPS study group. Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med 2009; 360: 2416-25.
    • (2009) N Engl J Med , vol.360 , pp. 2416-2425
    • Lachmann, H.J.1    Kone-Paut, I.2    Kuemmerle-Deschner, J.B.3
  • 76
    • 34247574122 scopus 로고    scopus 로고
    • Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
    • Kummer JA, Broekhuizen R, Everett H, et al. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem 2007; 55(5): 443-52.
    • (2007) J Histochem Cytochem , vol.55 , Issue.5 , pp. 443-452
    • Kummer, J.A.1    Broekhuizen, R.2    Everett, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.