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Volumn 2, Issue SPEC. ISS.2, 2010, Pages 64-70

TRPA1 as an analgesic target

Author keywords

AITC; Analgesic; AP18; Asthma; Formalin; Hc 030031; Inflammation; Neurogenic; Pain; TRP channel; TRPA1

Indexed keywords

A 967079; AMG 9090; AMILORIDE; ANALGESIC AGENT; ANALGESIC, ANTIINFLAMMATORY, ANTIRHEUMATIC AND ANTIGOUT AGENTS; AP 18; CAMPHOR; CHEM 5861528; GENTAMICIN; HC 030031; MENTHOL; PROTEIN INHIBITOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1 ANTAGONIST; UNCLASSIFIED DRUG;

EID: 79959995356     PISSN: None     EISSN: 18773818     Source Type: Journal    
DOI: 10.2174/1877381801002030064     Document Type: Review
Times cited : (14)

References (73)
  • 1
    • 0030777012 scopus 로고    scopus 로고
    • The capsaicin receptor: A heat-activated ion channel in the pain pathway
    • Caterina, M.J.; Schumacher, M.A.; Tominaga, M.; Rosen, T.A.; Levine, J.D.; Julius, D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 1997, 389(6653), 816-824.
    • (1997) Nature , vol.389 , Issue.6653 , pp. 816-824
    • Caterina, M.J.1    Schumacher, M.A.2    Tominaga, M.3    Rosen, T.A.4    Levine, J.D.5    Julius, D.6
  • 4
    • 0017335111 scopus 로고
    • Drosophila mutant with a transducer defect
    • Minke, B. Drosophila mutant with a transducer defect. Biophys. Struct. Mech., 1977, 3(1), 59-64.
    • (1977) Biophys. Struct. Mech , vol.3 , Issue.1 , pp. 59-64
    • Minke, B.1
  • 5
    • 0347504835 scopus 로고    scopus 로고
    • TRP channels as cellular sensors
    • Clapham, D.E. TRP channels as cellular sensors. Nature, 2003, 426(6966), 517-524.
    • (2003) Nature , vol.426 , Issue.6966 , pp. 517-524
    • Clapham, D.E.1
  • 6
    • 0033548702 scopus 로고    scopus 로고
    • An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts
    • Jaquemar, D.; Schenker, T.; Trueb, B. An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J. Biol. Chem., 1999, 274(11), 7325-7333.
    • (1999) J. Biol. Chem , vol.274 , Issue.11 , pp. 7325-7333
    • Jaquemar, D.1    Schenker, T.2    Trueb, B.3
  • 7
    • 26444582875 scopus 로고    scopus 로고
    • Drosophila TRP channels
    • Montell, C. Drosophila TRP channels. Pflugers Arch, 2005, 451(1), 19-28.
    • (2005) Pflugers Arch , vol.451 , Issue.1 , pp. 19-28
    • Montell, C.1
  • 9
    • 17644426325 scopus 로고    scopus 로고
    • Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing
    • Nagata, K.; Duggan, A.; Kumar, G.; Garcia-Anoveros, J. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J. Neurosci., 2005, 25(16), 4052-4061.
    • (2005) J. Neurosci , vol.25 , Issue.16 , pp. 4052-4061
    • Nagata, K.1    Duggan, A.2    Kumar, G.3    Garcia-Anoveros, J.4
  • 11
    • 59449105378 scopus 로고    scopus 로고
    • TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus
    • Yu, S.; Ouyang, A. TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus. Am. J. Physiol. Gastrointest. Liver Physiol., 2009, 296(2), G255-265.
    • (2009) Am. J. Physiol. Gastrointest. Liver Physiol , vol.296 , Issue.2
    • Yu, S.1    Ouyang, A.2
  • 12
    • 33847796216 scopus 로고    scopus 로고
    • Emergence of functional sensory subtypes as defined by transient receptor potential channel expression
    • Hjerling-Leffler, J.; Alqatari, M.; Ernfors, P.; Koltzenburg, M. Emergence of functional sensory subtypes as defined by transient receptor potential channel expression. J. Neurosci., 2007, 27(10), 2435-2443.
    • (2007) J. Neurosci , vol.27 , Issue.10 , pp. 2435-2443
    • Hjerling-Leffler, J.1    Alqatari, M.2    Ernfors, P.3    Koltzenburg, M.4
  • 13
    • 65549123596 scopus 로고    scopus 로고
    • TRPA1 modulates mechanotransduction in cutaneous sensory neurons
    • Kwan, K.Y.; Glazer, J.M.; Corey, D.P.; Rice, F.L.; Stucky, C.L. TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J. Neurosci., 2009, 29(15), 4808-4819.
    • (2009) J. Neurosci , vol.29 , Issue.15 , pp. 4808-4819
    • Kwan, K.Y.1    Glazer, J.M.2    Corey, D.P.3    Rice, F.L.4    Stucky, C.L.5
  • 14
    • 70349743888 scopus 로고    scopus 로고
    • An ice-cold TR(i)P to skin biology: The role of TRPA1 in human epidermal keratinocytes
    • Biro, T.; Kovacs, L. An ice-cold TR(i)P to skin biology: the role of TRPA1 in human epidermal keratinocytes. J. Invest. Dermatol., 2009, 129(9), 2096-2099.
    • (2009) J. Invest. Dermatol , vol.129 , Issue.9 , pp. 2096-2099
    • Biro, T.1    Kovacs, L.2
  • 16
    • 34249693460 scopus 로고    scopus 로고
    • Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury
    • Frederick, J.; Buck, M.E.; Matson, D.J.; Cortright, D.N. Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury. Biochem. Biophys. Res. Commun., 2007, 358(4), 1058-1064.
    • (2007) Biochem. Biophys. Res. Commun , vol.358 , Issue.4 , pp. 1058-1064
    • Frederick, J.1    Buck, M.E.2    Matson, D.J.3    Cortright, D.N.4
  • 17
    • 45849101211 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis
    • Yang, J.; Li, Y.; Zuo, X.; Zhen, Y.; Yu, Y.; Gao, L. Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis. Neurosci. Lett., 2008, 440(3), 237-241.
    • (2008) Neurosci. Lett , vol.440 , Issue.3 , pp. 237-241
    • Yang, J.1    Li, Y.2    Zuo, X.3    Zhen, Y.4    Yu, Y.5    Gao, L.6
  • 18
    • 70350212466 scopus 로고    scopus 로고
    • The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain
    • Caspani, O.; Zurborg, S.; Labuz, D.; Heppenstall, P.A. The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain. PLoS One, 2009, 4(10), e7383.
    • (2009) PLoS One , vol.4 , Issue.10
    • Caspani, O.1    Zurborg, S.2    Labuz, D.3    Heppenstall, P.A.4
  • 19
    • 67349114814 scopus 로고    scopus 로고
    • Differential regulation of TRP channels in a rat model of neuropathic pain
    • Staaf, S.; Oerther, S.; Lucas, G.; Mattsson, J.P.; Ernfors, P. Differential regulation of TRP channels in a rat model of neuropathic pain. Pain, 2009, 144(1-2), 187-199.
    • (2009) Pain , vol.144 , Issue.1-2 , pp. 187-199
    • Staaf, S.1    Oerther, S.2    Lucas, G.3    Mattsson, J.P.4    Ernfors, P.5
  • 20
    • 70449864498 scopus 로고    scopus 로고
    • Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
    • Schmidt, M.; Dubin, A.E.; Petrus, M.J.; Earley, T J.; Patapoutian, A. Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane. Neuron, 2009, 64(64), 498-509.
    • (2009) Neuron , vol.64 , Issue.64 , pp. 498-509
    • Schmidt, M.1    Dubin, A.E.2    Petrus, M.J.3    Earley, T.J.4    Patapoutian, A.5
  • 21
    • 25644433563 scopus 로고    scopus 로고
    • Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism
    • Xu, H.; Blair, N.T.; Clapham, D.E. Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J. Neurosci., 2005, 25(39), 8924-8937.
    • (2005) J. Neurosci , vol.25 , Issue.39 , pp. 8924-8937
    • Xu, H.1    Blair, N.T.2    Clapham, D.E.3
  • 22
    • 34548610605 scopus 로고    scopus 로고
    • Bimodal action of menthol on the transient receptor potential channel TRPA1
    • Karashima, Y.; Damann, N.; Prenen, J.; Talavera, K.; Segal, A.; Voets, T.; Nilius, B. Bimodal action of menthol on the transient receptor potential channel TRPA1. J. Neurosci., 2007, 27(37), 9874-9884.
    • (2007) J. Neurosci , vol.27 , Issue.37 , pp. 9874-9884
    • Karashima, Y.1    Damann, N.2    Prenen, J.3    Talavera, K.4    Segal, A.5    Voets, T.6    Nilius, B.7
  • 25
    • 67650085850 scopus 로고    scopus 로고
    • Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channel in diabetic animals
    • Wei, H.; Hamalainen, M.M.; Saarnilehto, M.; Koivisto, A.; Pertovaara, A. Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channel in diabetic animals. Anesthesiology, 2009, 111(1), 147-154.
    • (2009) Anesthesiology , vol.111 , Issue.1 , pp. 147-154
    • Wei, H.1    Hamalainen, M.M.2    Saarnilehto, M.3    Koivisto, A.4    Pertovaara, A.5
  • 27
    • 38949149310 scopus 로고    scopus 로고
    • Species-specific pharmacology of Trichloro (sulfanyl) ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists
    • Klionsky, L.; Tamir, R.; Gao, B.; Wang, W.; Immke, D.C.; Nishimura, N.; Gavva, N.R. Species-specific pharmacology of Trichloro (sulfanyl) ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists. Mol. Pain, 2007, 3, 39.
    • (2007) Mol. Pain , vol.3 , pp. 39
    • Klionsky, L.1    Tamir, R.2    Gao, B.3    Wang, W.4    Immke, D.C.5    Nishimura, N.6    Gavva, N.R.7
  • 30
    • 33646061333 scopus 로고    scopus 로고
    • TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction
    • Kwan, K.Y.; Allchorne, A.J.; Vollrath, M.A.; Christensen, A.P.; Zhang, D.S.; Woolf, C.J.; Corey, D.P. TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction. Neuron, 2006, 50, 277-289.
    • (2006) Neuron , vol.50 , pp. 277-289
    • Kwan, K.Y.1    Allchorne, A.J.2    Vollrath, M.A.3    Christensen, A.P.4    Zhang, D.S.5    Woolf, C.J.6    Corey, D.P.7
  • 32
    • 77149125545 scopus 로고    scopus 로고
    • A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea
    • Asai, Y.; Holt, J.R.; Geleoc, G.S. A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea. J. Assoc. Res. Otolaryngol., 2010, 11(1), 27-37.
    • (2010) J. Assoc. Res. Otolaryngol , vol.11 , Issue.1 , pp. 27-37
    • Asai, Y.1    Holt, J.R.2    Geleoc, G.S.3
  • 36
  • 37
    • 33846692923 scopus 로고    scopus 로고
    • Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
    • Macpherson, L.J.; Dubin, A.E.; Evans, M.J.; Marr, F.; Schultz, P.G.; Cravatt, B.F.; Patapoutian, A. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature, 2007, 445(7127), 541-545.
    • (2007) Nature , vol.445 , Issue.7127 , pp. 541-545
    • Macpherson, L.J.1    Dubin, A.E.2    Evans, M.J.3    Marr, F.4    Schultz, P.G.5    Cravatt, B.F.6    Patapoutian, A.7
  • 38
    • 56449110894 scopus 로고    scopus 로고
    • HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity
    • Eid, S.R.; Crown, E.D.; Moore, E.L.; Liang, H.A.; Choong, K.C.; Dima, S.; Henze, D.A.; Kane, S.A.; Urban, M.O. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol. Pain, 2008, 4, 48.
    • (2008) Mol. Pain , vol.4 , pp. 48
    • Eid, S.R.1    Crown, E.D.2    Moore, E.L.3    Liang, H.A.4    Choong, K.C.5    Dima, S.6    Henze, D.A.7    Kane, S.A.8    Urban, M.O.9
  • 42
    • 65349163523 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases
    • Bessac, B.F.; Sivula, M.; von Hehn, C.A.; Caceres, A.I.; Escalera, J.; Jordt, S.E. Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases. FASEB J., 2009, 23(4), 1102-1114.
    • (2009) FASEB J , vol.23 , Issue.4 , pp. 1102-1114
    • Bessac, B.F.1    Sivula, M.2    von Hehn, C.A.3    Caceres, A.I.4    Escalera, J.5    Jordt, S.E.6
  • 43
    • 65649141656 scopus 로고    scopus 로고
    • Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors
    • Kerstein, P.C.; del Camino, D.; Moran, M.M.; Stucky, C.L. Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors. Mol. Pain, 2009, 5, 19.
    • (2009) Mol. Pain , vol.5 , pp. 19
    • Kerstein, P.C.1    del Camino, D.2    Moran, M.M.3    Stucky, C.L.4
  • 45
    • 76749102378 scopus 로고    scopus 로고
    • Multiple Cation Channels Mediate Increases in Intracellular Calcium Induced by the Volatile Irritant, Trans-2-Pentenal in Rat Trigeminal Neurons
    • Inoue, T.; Bryant, B.P. Multiple Cation Channels Mediate Increases in Intracellular Calcium Induced by the Volatile Irritant, Trans-2-Pentenal in Rat Trigeminal Neurons. Cell Mol. Neurobiol., 2010, 30(1), 35-41.
    • (2010) Cell Mol. Neurobiol , vol.30 , Issue.1 , pp. 35-41
    • Inoue, T.1    Bryant, B.P.2
  • 46
    • 48949120476 scopus 로고    scopus 로고
    • Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal
    • Taylor-Clark, T.E.; McAlexander, M.A.; Nassenstein, C.; Sheardown, S.A.; Wilson, S.; Thornton, J.; Carr, M.J.; Undem, B.J. Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal. J. Physiol., 2008, 586(14), 3447-3459.
    • (2008) J. Physiol , vol.586 , Issue.14 , pp. 3447-3459
    • Taylor-Clark, T.E.1    McAlexander, M.A.2    Nassenstein, C.3    Sheardown, S.A.4    Wilson, S.5    Thornton, J.6    Carr, M.J.7    Undem, B.J.8
  • 48
    • 38549092780 scopus 로고    scopus 로고
    • Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1)
    • Taylor-Clark, T.E.; Undem, B.J.; Macglashan, D.W. Jr.; Ghatta, S.; Carr, M.J.; McAlexander, M.A. Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1). Mol. Pharmacol., 2008, 73(2), 274-281.
    • (2008) Mol. Pharmacol , vol.73 , Issue.2 , pp. 274-281
    • Taylor-Clark, T.E.1    Undem, B.J.2    Macglashan Jr., D.W.3    Ghatta, S.4    Carr, M.J.5    McAlexander, M.A.6
  • 51
    • 70449587066 scopus 로고    scopus 로고
    • TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice
    • Miyamoto, T.; Dubin, A.E.; Petrus, M.J.; Patapoutian, A. TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. PLoS One, 2009, 4(10), e7596.
    • (2009) PLoS One , vol.4 , Issue.10
    • Miyamoto, T.1    Dubin, A.E.2    Petrus, M.J.3    Patapoutian, A.4
  • 55
    • 34250379970 scopus 로고    scopus 로고
    • Transient receptor potential channel A1 is directly gated by calcium ions
    • Doerner, J.F.; Gisselmann, G.; Hatt, H.; Wetzel, C.H. Transient receptor potential channel A1 is directly gated by calcium ions. J. Biol. Chem., 2007, 282(18), 13180-13189.
    • (2007) J. Biol. Chem , vol.282 , Issue.18 , pp. 13180-13189
    • Doerner, J.F.1    Gisselmann, G.2    Hatt, H.3    Wetzel, C.H.4
  • 56
    • 57749107691 scopus 로고    scopus 로고
    • The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions
    • Wang, Y.Y.; Chang, R.B.; Waters, H.N.; McKemy, D.D.; Liman, E.R. The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions. J. Biol. Chem., 2008, 283(47), 32691-32703.
    • (2008) J. Biol. Chem , vol.283 , Issue.47 , pp. 32691-32703
    • Wang, Y.Y.1    Chang, R.B.2    Waters, H.N.3    McKemy, D.D.4    Liman, E.R.5
  • 63
    • 0030561917 scopus 로고    scopus 로고
    • Anti-inflammatory and antinociceptive effect of different somatostatin-analogs
    • Helyes, Z.; Pinter, E.; Szolcsanyi, J.; Horvath, J. Anti-inflammatory and antinociceptive effect of different somatostatin-analogs. Neurobiology (Bp), 1996, 4(1-2), 115-117.
    • (1996) Neurobiology (Bp) , vol.4 , Issue.1-2 , pp. 115-117
    • Helyes, Z.1    Pinter, E.2    Szolcsanyi, J.3    Horvath, J.4
  • 64
    • 67649482336 scopus 로고    scopus 로고
    • Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia
    • Ro, J.Y.; Lee, J.S.; Zhang, Y. Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain, 2009, 144(3), 270-277.
    • (2009) Pain , vol.144 , Issue.3 , pp. 270-277
    • Ro, J.Y.1    Lee, J.S.2    Zhang, Y.3
  • 66
    • 57749111494 scopus 로고    scopus 로고
    • Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control
    • Bessac, B.F.; Jordt, S.E. Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. Physiology (Bethesda), 2008, 23, 360-370.
    • (2008) Physiology (Bethesda) , vol.23 , pp. 360-370
    • Bessac, B.F.1    Jordt, S.E.2
  • 70
    • 66249101637 scopus 로고    scopus 로고
    • Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+
    • Andersson, D.A.; Gentry, C.; Moss, S.; Bevan, S. Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+. Proc. Natl. Acad. Sci. USA, 2009, 106(20), 8374-8379.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.20 , pp. 8374-8379
    • Andersson, D.A.1    Gentry, C.2    Moss, S.3    Bevan, S.4


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