Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice

Molecular Therapy

Volumn 19, Issue 7, 2011, Pages 1295-1303

  Yin, Haifang ^a,b   Saleh, Amer F ^c   Betts, Corinne ^a   Camelliti, Patrizia ^a   Seow, Yiqi ^a   Ashraf, Shirin ^a   Arzumanov, Andrey ^c   Hammond, Suzan ^a   Merritt, Thomas ^a   Gait, Michael J ^c   Wood, Matthew J A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DYSTROPHIN; MORPHOLINE DERIVATIVE; PEPTIDE NUCLEIC ACID; PHOSPHORODIAMIDATE MORPHOLINO; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DMD GENE; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DUCHENNE MUSCULAR DYSTROPHY; EXON SKIPPING; GENE; GENE MUTATION; GENETIC TRANSDUCTION; MOUSE; NONHUMAN; OPEN READING FRAME; PHENOTYPE; SINGLE DRUG DOSE; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALS; BLOTTING, WESTERN; EXONS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED MDX; MUSCULAR DYSTROPHY, DUCHENNE; MYOCARDIUM; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDES; TRANSDUCTION, GENETIC;

MUS;

EID: 79959995255     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.79     Document Type: Article

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