메뉴 건너뛰기




Volumn 4, Issue 1, 2011, Pages

Thrombospondin 1 in hypoxia-conditioned media blocks the growth of human microvascular endothelial cells and is increased in systemic sclerosis tissues

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN BINDING PROTEIN; RECOMBINANT PROTEIN; RECOMBINANT THROMBOSPONDIN 1; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79959984675     PISSN: None     EISSN: 17551536     Source Type: Journal    
DOI: 10.1186/1755-1536-4-13     Document Type: Article
Times cited : (16)

References (34)
  • 1
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: a prototypic multisystem fibrotic disorder
    • 10.1172/JCI31139, 1804347, 17332883
    • Varga J, Abraham D. Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 2007, 117:557-567. 10.1172/JCI31139, 1804347, 17332883.
    • (2007) J Clin Invest , vol.117 , pp. 557-567
    • Varga, J.1    Abraham, D.2
  • 2
    • 0018749284 scopus 로고
    • Endothelial injury in scleroderma
    • 10.1084/jem.149.6.1326, 2184886, 312896
    • Kahaleh MB, Sherer GK, LeRoy EC. Endothelial injury in scleroderma. J Exp Med 1979, 149:1326-1335. 10.1084/jem.149.6.1326, 2184886, 312896.
    • (1979) J Exp Med , vol.149 , pp. 1326-1335
    • Kahaleh, M.B.1    Sherer, G.K.2    LeRoy, E.C.3
  • 3
    • 0030031147 scopus 로고    scopus 로고
    • IgG antiendothelial cell autoantibodies from scleroderma patients induce leukocyte adhesion to human vascular endothelial cells in vitro: induction of adhesion molecule expression and involvement of endothelium-derived cytokines
    • 10.1172/JCI118377, 507068, 8550821
    • Carvalho D, Savage CO, Black CM, Pearson JD. IgG antiendothelial cell autoantibodies from scleroderma patients induce leukocyte adhesion to human vascular endothelial cells in vitro: induction of adhesion molecule expression and involvement of endothelium-derived cytokines. J Clin Invest 1996, 97:111-119. 10.1172/JCI118377, 507068, 8550821.
    • (1996) J Clin Invest , vol.97 , pp. 111-119
    • Carvalho, D.1    Savage, C.O.2    Black, C.M.3    Pearson, J.D.4
  • 4
    • 0033758304 scopus 로고    scopus 로고
    • Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95
    • 10.1002/1529-0131(200011)43:11<2550::AID-ANR24>3.0.CO;2-H, 11083280
    • Sgonc R, Gruschwitz MS, Boeck G, Sepp N, Gruber J, Wick G. Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95. Arthritis Rheum 2000, 43:2550-2562. 10.1002/1529-0131(200011)43:11<2550::AID-ANR24>3.0.CO;2-H, 11083280.
    • (2000) Arthritis Rheum , vol.43 , pp. 2550-2562
    • Sgonc, R.1    Gruschwitz, M.S.2    Boeck, G.3    Sepp, N.4    Gruber, J.5    Wick, G.6
  • 5
    • 0141676369 scopus 로고    scopus 로고
    • In vivo analysis of the apoptosis-inducing effect of anti-endothelial cell antibodies in systemic sclerosis by the chorioallantoic membrane assay
    • 10.1002/art.11179, 13130480
    • Worda M, Sgonc R, Dietrich H, Niederegger H, Sundick RS, Gershwin ME, Wick G. In vivo analysis of the apoptosis-inducing effect of anti-endothelial cell antibodies in systemic sclerosis by the chorioallantoic membrane assay. Arthritis Rheum 2003, 48:2605-2614. 10.1002/art.11179, 13130480.
    • (2003) Arthritis Rheum , vol.48 , pp. 2605-2614
    • Worda, M.1    Sgonc, R.2    Dietrich, H.3    Niederegger, H.4    Sundick, R.S.5    Gershwin, M.E.6    Wick, G.7
  • 6
    • 33745877171 scopus 로고    scopus 로고
    • Induction of apoptosis and fibrillin 1 expression in human dermal endothelial cells by scleroderma sera containing anti-endothelial cell antibodies
    • 10.1002/art.21952, 16802364
    • Ahmed SS, Tan FK, Arnett FC, Jin L, Geng YJ. Induction of apoptosis and fibrillin 1 expression in human dermal endothelial cells by scleroderma sera containing anti-endothelial cell antibodies. Arthritis Rheum 2006, 54:2250-2262. 10.1002/art.21952, 16802364.
    • (2006) Arthritis Rheum , vol.54 , pp. 2250-2262
    • Ahmed, S.S.1    Tan, F.K.2    Arnett, F.C.3    Jin, L.4    Geng, Y.J.5
  • 7
    • 0029946665 scopus 로고    scopus 로고
    • Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma
    • 10.1002/art.1780390711, 8670323
    • Stein CM, Tanner SB, Awad JA, Roberts LJ, Morrow JD. Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. Arthritis Rheum 1996, 39:1146-1150. 10.1002/art.1780390711, 8670323.
    • (1996) Arthritis Rheum , vol.39 , pp. 1146-1150
    • Stein, C.M.1    Tanner, S.B.2    Awad, J.A.3    Roberts, L.J.4    Morrow, J.D.5
  • 8
    • 33745620189 scopus 로고    scopus 로고
    • Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis
    • Ogawa F, Shimizu K, Muroi E, Hara T, Hasegawa M, Takehara K, Sato S. Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis. Rheumatology (Oxford) 2006, 45:815-818.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 815-818
    • Ogawa, F.1    Shimizu, K.2    Muroi, E.3    Hara, T.4    Hasegawa, M.5    Takehara, K.6    Sato, S.7
  • 9
    • 33646789483 scopus 로고    scopus 로고
    • Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine
    • Dooley A, Gao B, Bradley N, Abraham DJ, Black CM, Jacobs M, Bruckdorfer KR. Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine. Rheumatology (Oxford) 2006, 45:676-684.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 676-684
    • Dooley, A.1    Gao, B.2    Bradley, N.3    Abraham, D.J.4    Black, C.M.5    Jacobs, M.6    Bruckdorfer, K.R.7
  • 10
    • 84892072210 scopus 로고    scopus 로고
    • Vascular disease in scleroderma
    • Berlin: Springer, Abraham A, Handler C, Dashwood M, Coghlan JG
    • Nuttall A, Derrett-Smith E, Stratton R. Vascular disease in scleroderma. Advances in Vascular Medicine 2010, 315-334. Berlin: Springer, Abraham A, Handler C, Dashwood M, Coghlan JG.
    • (2010) Advances in Vascular Medicine , pp. 315-334
    • Nuttall, A.1    Derrett-Smith, E.2    Stratton, R.3
  • 12
    • 30744438818 scopus 로고    scopus 로고
    • The differential expression of VEGF, VEGFR-2 and GLUT-1 proteins in disease subtypes of systemic sclerosis
    • 10.1016/j.humpath.2005.10.007, 16426919
    • Davies CA, Jeziorska M, Freemont AJ, Herrick AL. The differential expression of VEGF, VEGFR-2 and GLUT-1 proteins in disease subtypes of systemic sclerosis. Hum Pathol 2006, 37:190-197. 10.1016/j.humpath.2005.10.007, 16426919.
    • (2006) Hum Pathol , vol.37 , pp. 190-197
    • Davies, C.A.1    Jeziorska, M.2    Freemont, A.J.3    Herrick, A.L.4
  • 13
    • 65649133084 scopus 로고    scopus 로고
    • Abnormalities in the regulators of angiogenesis in patients with scleroderma
    • 10.3899/jrheum.080516, 19228661
    • Hummers LK, Hall A, Wigley FM, Simons M. Abnormalities in the regulators of angiogenesis in patients with scleroderma. J Rheumatol 2009, 36:576-582. 10.3899/jrheum.080516, 19228661.
    • (2009) J Rheumatol , vol.36 , pp. 576-582
    • Hummers, L.K.1    Hall, A.2    Wigley, F.M.3    Simons, M.4
  • 14
    • 0033850755 scopus 로고    scopus 로고
    • Increased concentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis
    • 10.1002/1529-0131(200004)43:4<889::AID-ANR21>3.0.CO;2-5, 10765935
    • Hebbar M, Peyrat JP, Hornez L, Hatron PY, Hachulla E, Devulder B. Increased concentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis. Arthritis Rheum 2000, 43:889-893. 10.1002/1529-0131(200004)43:4<889::AID-ANR21>3.0.CO;2-5, 10765935.
    • (2000) Arthritis Rheum , vol.43 , pp. 889-893
    • Hebbar, M.1    Peyrat, J.P.2    Hornez, L.3    Hatron, P.Y.4    Hachulla, E.5    Devulder, B.6
  • 15
    • 0036897408 scopus 로고    scopus 로고
    • Increased circulating concentrations of the counteradhesive proteins SPARC and thrombospondin-1 in systemic sclerosis (scleroderma): relationship to platelet and endothelial cell activation
    • Macko RF, Gelber AC, Young BA, Lowitt MH, White B, Wigley FM, Goldblum SE. Increased circulating concentrations of the counteradhesive proteins SPARC and thrombospondin-1 in systemic sclerosis (scleroderma): relationship to platelet and endothelial cell activation. J Rheumatol 2002, 29:2565-2570.
    • (2002) J Rheumatol , vol.29 , pp. 2565-2570
    • Macko, R.F.1    Gelber, A.C.2    Young, B.A.3    Lowitt, M.H.4    White, B.5    Wigley, F.M.6    Goldblum, S.E.7
  • 17
    • 0026677532 scopus 로고
    • THMEC-1: establishment of an immortalized human microvascular endothelial cell line
    • 10.1111/1523-1747.ep12613748, 1361507
    • Ades EW, Candal FJ, Swerlick RA, George VG, Summers S, Bosse DC, Lawley TJ. THMEC-1: establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol 1992, 99:683-690. 10.1111/1523-1747.ep12613748, 1361507.
    • (1992) J Invest Dermatol , vol.99 , pp. 683-690
    • Ades, E.W.1    Candal, F.J.2    Swerlick, R.A.3    George, V.G.4    Summers, S.5    Bosse, D.C.6    Lawley, T.J.7
  • 18
    • 0018253429 scopus 로고
    • Isolation and characterization of a high molecular weight glycoprotein from human blood platelets
    • Lawler JW, Slayter HS, Coligan JE. Isolation and characterization of a high molecular weight glycoprotein from human blood platelets. J Biol Chem 1978, 253:8609-8616.
    • (1978) J Biol Chem , vol.253 , pp. 8609-8616
    • Lawler, J.W.1    Slayter, H.S.2    Coligan, J.E.3
  • 19
    • 0026452515 scopus 로고
    • Thrombospondins: structure and regulation of expression
    • Bornstein P. Thrombospondins: structure and regulation of expression. FASEB J 1992, 6:3290-3299.
    • (1992) FASEB J , vol.6 , pp. 3290-3299
    • Bornstein, P.1
  • 20
    • 77955978745 scopus 로고    scopus 로고
    • The evolution of thrombospondins and their ligand-binding activities
    • 10.1093/molbev/msq107, 20427418
    • Bentley AA, Adams JC. The evolution of thrombospondins and their ligand-binding activities. Mol Biol Evol 2010, 27:2187-2197. 10.1093/molbev/msq107, 20427418.
    • (2010) Mol Biol Evol , vol.27 , pp. 2187-2197
    • Bentley, A.A.1    Adams, J.C.2
  • 21
    • 0021332342 scopus 로고
    • Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen
    • 10.1083/jcb.98.2.646, 2113082, 6693501
    • Mumby SM, Raugi GJ, Bornstein P. Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen. J Cell Biol 1984, 98:646-652. 10.1083/jcb.98.2.646, 2113082, 6693501.
    • (1984) J Cell Biol , vol.98 , pp. 646-652
    • Mumby, S.M.1    Raugi, G.J.2    Bornstein, P.3
  • 22
    • 0020366972 scopus 로고
    • Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen
    • 10.1016/0092-8674(82)90425-1, 7159924
    • Lahav J, Schwartz MA, Hynes RO. Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell 1982, 31:253-262. 10.1016/0092-8674(82)90425-1, 7159924.
    • (1982) Cell , vol.31 , pp. 253-262
    • Lahav, J.1    Schwartz, M.A.2    Hynes, R.O.3
  • 23
    • 0020313151 scopus 로고
    • Synthesis and secretion of thrombospondin by cultured human endothelial cells
    • 10.1083/jcb.93.2.343, 2112841, 7096442
    • Mosher DF, Doyle MJ, Jaffe EA. Synthesis and secretion of thrombospondin by cultured human endothelial cells. J Cell Biol 1982, 93:343-348. 10.1083/jcb.93.2.343, 2112841, 7096442.
    • (1982) J Cell Biol , vol.93 , pp. 343-348
    • Mosher, D.F.1    Doyle, M.J.2    Jaffe, E.A.3
  • 24
    • 0023157005 scopus 로고
    • Human keratinocytes synthesize and secrete the extracellular matrix protein, thrombospondin
    • 10.1111/1523-1747.ep12525350, 3543145
    • Wikner NE, Dixit VM, Frazier WA, Clark RA. Human keratinocytes synthesize and secrete the extracellular matrix protein, thrombospondin. J Invest Dermatol 1987, 88:207-211. 10.1111/1523-1747.ep12525350, 3543145.
    • (1987) J Invest Dermatol , vol.88 , pp. 207-211
    • Wikner, N.E.1    Dixit, V.M.2    Frazier, W.A.3    Clark, R.A.4
  • 25
    • 0026453281 scopus 로고
    • Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
    • 10.1172/JCI116019, 443198, 1383273
    • Savill J, Hogg N, Ren Y, Haslett C. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest 1992, 90:1513-1522. 10.1172/JCI116019, 443198, 1383273.
    • (1992) J Clin Invest , vol.90 , pp. 1513-1522
    • Savill, J.1    Hogg, N.2    Ren, Y.3    Haslett, C.4
  • 26
    • 0036731861 scopus 로고    scopus 로고
    • The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice
    • 10.1016/S0002-9440(10)64243-5, 1867266, 12213711
    • Agah A, Kyriakides TR, Lawler J, Bornstein P. The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. Am J Pathol 2002, 161:831-839. 10.1016/S0002-9440(10)64243-5, 1867266, 12213711.
    • (2002) Am J Pathol , vol.161 , pp. 831-839
    • Agah, A.1    Kyriakides, T.R.2    Lawler, J.3    Bornstein, P.4
  • 28
    • 0343091300 scopus 로고    scopus 로고
    • Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway
    • 10.1159/000025733, 10859480
    • Nör JE, Mitra RS, Sutorik MM, Mooney DJ, Castle VP, Polverini PJ. Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway. J Vasc Res 2000, 37:209-218. 10.1159/000025733, 10859480.
    • (2000) J Vasc Res , vol.37 , pp. 209-218
    • Nör, J.E.1    Mitra, R.S.2    Sutorik, M.M.3    Mooney, D.J.4    Castle, V.P.5    Polverini, P.J.6
  • 29
    • 0032387693 scopus 로고    scopus 로고
    • Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells
    • 10.1016/S0022-2143(98)90131-7, 9851743
    • Phelan MW, Forman LW, Perrine SP, Faller DV. Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells. J Lab Clin Med 1998, 132:519-529. 10.1016/S0022-2143(98)90131-7, 9851743.
    • (1998) J Lab Clin Med , vol.132 , pp. 519-529
    • Phelan, M.W.1    Forman, L.W.2    Perrine, S.P.3    Faller, D.V.4
  • 30
    • 70349658097 scopus 로고    scopus 로고
    • Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level
    • 10.1096/fj.09-131649, 2747678, 19528255
    • Zhang X, Kazerounian S, Duquette M, Perruzzi C, Nagy JA, Dvorak HF, Parangi S, Lawler J. Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level. FASEB J 2009, 23:3368-3376. 10.1096/fj.09-131649, 2747678, 19528255.
    • (2009) FASEB J , vol.23 , pp. 3368-3376
    • Zhang, X.1    Kazerounian, S.2    Duquette, M.3    Perruzzi, C.4    Nagy, J.A.5    Dvorak, H.F.6    Parangi, S.7    Lawler, J.8
  • 31
    • 75749095228 scopus 로고    scopus 로고
    • A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis
    • 3018285, 20112379
    • Farina G, Lafyatis D, Lemaire R, Lafyatis R. A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis. Arthritis Rheum 2010, 62:580-588. 3018285, 20112379.
    • (2010) Arthritis Rheum , vol.62 , pp. 580-588
    • Farina, G.1    Lafyatis, D.2    Lemaire, R.3    Lafyatis, R.4
  • 33
    • 17844395977 scopus 로고    scopus 로고
    • Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-β signaling in cultured scleroderma fibroblasts
    • 10.1016/S0002-9440(10)62362-0, 1606399, 15855645
    • Mimura Y, Ihn H, Jinnin M, Asano Y, Yamane K, Tamaki K. Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-β signaling in cultured scleroderma fibroblasts. Am J Pathol 2005, 166:1451-1463. 10.1016/S0002-9440(10)62362-0, 1606399, 15855645.
    • (2005) Am J Pathol , vol.166 , pp. 1451-1463
    • Mimura, Y.1    Ihn, H.2    Jinnin, M.3    Asano, Y.4    Yamane, K.5    Tamaki, K.6
  • 34
    • 27644494309 scopus 로고    scopus 로고
    • Critical overexpression of thrombospondin 1 in chronic leg ischaemia
    • 10.1002/path.1833, 16110458
    • Favier J, Germain S, Emmerich J, Corvol P, Gasc JM. Critical overexpression of thrombospondin 1 in chronic leg ischaemia. J Pathol 2005, 207:358-366. 10.1002/path.1833, 16110458.
    • (2005) J Pathol , vol.207 , pp. 358-366
    • Favier, J.1    Germain, S.2    Emmerich, J.3    Corvol, P.4    Gasc, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.