Heat shock protein 90 mediates anti-apoptotic effect of diazoxide by preventing the cleavage of Bid in hypothermic preservation rat hearts

Journal of Heart and Lung Transplantation

Volumn 30, Issue 8, 2011, Pages 928-934

  Yang, Fan ^a   Chen, Wen Liang ^a   Zheng, Ming Zhi ^a   Yu, Guo Wei ^b   Xu, He Jing ^c   Shen, Yue Liang ^a   Chen, Ying Ying ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; Bid; heart preservation; heat shock protein 90; mitochondrial ATP sensitive potassium channel

Indexed keywords

DIAZOXIDE; HEAT SHOCK PROTEIN 90; PROTEIN BID; TANESPIMYCIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; DRUG EFFECT; DRUG MECHANISM; HEART; HEART FUNCTION; HEART MUSCLE REPERFUSION; HEART VENTRICLE PRESSURE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; COLD TEMPERATURE; CONNEXIN 43; DIAZOXIDE; DISACCHARIDES; ELECTROLYTES; GLUTAMATES; GLUTATHIONE; HEART TRANSPLANTATION; HISTIDINE; HSP90 HEAT-SHOCK PROTEINS; MALE; MANNITOL; MITOCHONDRIA, HEART; MODELS, ANIMAL; MYOCARDIUM; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 79959970967     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2011.04.001     Document Type: Article

References (30)

1. Z.K. Yan, Z.B. Hu, X.H. Pan, Y.Y. Chen, X.M. Zhang, and Y.L. Shen Diazoxide supplemented Celsior solution improves hypothermic heart preservation effect in rat through activation of mitochondrial ATP-sensitive potassium channel Pharm Biol 47 2009 1060 1066
2. D. Lanneau, A. de Thonel, S. Maurel, C. Didelot, and C. Garrido Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27 Prion 1 2007 53 60
3. E.L. Holmuhamedov, S. Jovanovic, P.P. Dzeja, A. Jovanovic, and A. Terzic Mitochondrial ATP-sensitive K+ channels modulate cardiac mitochondrial function Am J Physiol 275 1998 H1567 H1576
4. M. Hicks, A. Hing, L. Gao, J. Ryan, and P.S. Macdonald Organ preservation Methods Mol Biol 333 2006 331 374
5. M.A. Deja, M. Malinowski, and K.S. Golba Diazoxide protects myocardial mitochondria, metabolism, and function during cardiac surgery: a double-blind randomized feasibility study of diazoxide-supplemented cardioplegia J Thorac Cardiovasc Surg 137 2009 997 1004 e1-2
6. J. Huang, K. Nakamura, and Y. Ito Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rats Circulation 112 2005 76 83 (Pubitemid 40962572)
7. M. Ichinose, H. Yonemochi, T. Sato, and T. Saikawa Diazoxide triggers cardioprotection against apoptosis induced by oxidative stress Am J Physiol Heart Circ Physiol 284 2003 H2235 H2241
8. E. Takashi, Y. Wang, and M. Ashraf Activation of mitochondrial K(ATP) channel elicits late preconditioning against myocardial infarction via protein kinase C signaling pathway Circ Res 85 1999 1146 1153 (Pubitemid 30430619)
9. A.V. Kuznetsov, S. Schneeberger, and R. Seiler Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion Am J Physiol Heart Circ Physiol 286 2004 H1633 H1641
10. N.R. Brady, A. Hamacher-Brady, and R.A. Gottlieb Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors Biochim Biophys Acta 1757 2006 667 678 (Pubitemid 43993858)
11. L.P. Billen, A. Shamas-Din, and D.W. Andrews Bid: a Bax-like BH3 protein Oncogene 27 suppl 1 2008 S93 S104
12. H. Li, H. Zhu, C.J. Xu, and J. Yuan Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 94 1998 491 501 (Pubitemid 28391865)
13. A. Gross, X.M. Yin, and K. Wang Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death J Biol Chem 274 1999 1156 1163
14. S.D. Lee, W.W. Kuo, and D.T. Bau The coexistence of nocturnal sustained hypoxia and obesity additively increases cardiac apoptosis J Appl Physiol 104 2008 1144 1153
15. S.B. Haudek, G.E. Taffet, M.D. Schneider, and D.L. Mann TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways J Clin Invest 117 2007 2692 2701 (Pubitemid 47494369)
16. H.M. Zhang, B. Yanagawa, and P. Cheung Nip21 gene expression reduces coxsackievirus B3 replication by promoting apoptotic cell death via a mitochondria-dependent pathway Circ Res 90 2002 1251 1258 (Pubitemid 34787406)
17. X. Yi, X.M. Yin, and Z. Dong Inhibition of Bid-induced apoptosis by Bcl-2 tBid insertion, Bax translocation, and Bax/Bak oligomerization suppressed J Biol Chem 278 2003 16992 16999 (Pubitemid 36799574)
18. U. Laufs Beyond lipid-lowering: effects of statins on endothelial nitric oxide Eur J Clin Pharmacol 58 2003 719 731 (Pubitemid 36399228)
19. A. Rodriguez-Sinovas, K. Boengler, and A. Cabestrero Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection Circ Res 99 2006 93 101 (Pubitemid 44297060)
20. C.C. Gray, M. Amrani, and M.H. Yacoub Heat stress proteins and myocardial protection: experimental model or potential clinical tool? Int J Biochem Cell Biol 31 1999 559 573 (Pubitemid 29219402)
21. E. Schmitt, M. Gehrmann, M. Brunet, G. Multhoff, and C. Garrido Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy J Leukoc Biol 81 2007 15 27 (Pubitemid 46021247)
22. C. Zhao, and E. Wang Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts Cell Signal 16 2004 313 321 (Pubitemid 37542406)
23. G.V. Georgakis, Y. Li, and A. Younes The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9 Br J Haematol 135 2006 68 71 (Pubitemid 44337664)
24. K. Boengler, G. Dodoni, and A. Rodriguez-Sinovas Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning Cardiovasc Res 67 2005 234 244 (Pubitemid 40943616)
25. M.A. Beardslee, D.L. Lerner, and P.N. Tadros Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia Circ Res 87 2000 656 662
26. A.F. Bruce, S. Rothery, E. Dupont, and N.J. Severs Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1 Cardiovasc Res 77 2008 757 765 (Pubitemid 351301863)
27. S. Dhein, L. Polontchouk, A. Salameh, and J.A. Haefliger Pharmacological modulation and differential regulation of the cardiac gap junction proteins connexin 43 and connexin 40 Biol Cell 94 2002 409 422 (Pubitemid 36113693)
28. F.R. Heinzel, Y. Luo, and X. Li Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice Circ Res 97 2005 583 586 (Pubitemid 41361749)
29. J.H. Lin, J. Yang, and S. Liu Connexin mediates gap junction-independent resistance to cellular injury J Neurosci 23 2003 430 441 (Pubitemid 36139542)
30. F. Goubaeva, M. Mikami, S. Giardina, B. Ding, J. Abe, and J. Yang Cardiac mitochondrial connexin 43 regulates apoptosis Biochem Biophys Res Commun 352 2007 97 103 (Pubitemid 44821099)