Cytolethal distending toxin: A conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages

Microbiology

Volumn 157, Issue 7, 2011, Pages 1521-1875

  Jinadasa, Rasika N ^a   Bloom, Stephen E ^a   Weiss, Robert S ^a   Duhamel, Gerald E ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLETHAL DISTENDING TOXIN; CYTOLETHAL DISTENDING TOXIN B; DEOXYRIBONUCLEASE I; DOUBLE STRANDED DNA; NUCLEASE; PHOSPHATASE; PROTEIN P53; UNCLASSIFIED DRUG; BACTERIAL TOXIN; MUTAGENIC AGENT; PHOSPHODIESTERASE;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; APOPTOSIS; BACTERIAL GENE; CAMPYLOBACTER JEJUNI; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL DEATH; CELL LINEAGE; DOUBLE STRANDED DNA BREAK; ESCHERICHIA COLI; HAEMOPHILUS DUCREYI; HUMAN; MAMMAL CELL; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SHIGELLA DYSENTERIAE; CELL CYCLE; CELL LINE; CHEMISTRY; DNA REPAIR; GENETICS; GRAM NEGATIVE BACTERIUM; METABOLISM; PATHOGENICITY;

BACTERIA (MICROORGANISMS); MAMMALIA; NEGIBACTERIA;

APOPTOSIS; BACTERIAL TOXINS; CELL CYCLE; CELL LINE; DEOXYRIBONUCLEASE I; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; GRAM-NEGATIVE BACTERIA; MUTAGENS; PHOSPHORIC DIESTER HYDROLASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79959945829     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.049536-0     Document Type: Review

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