Possible involvement of β-endorphin in a loss of the coordinated balance of μ-opioid receptors trafficking processes by fentanyl

Synapse

Volumn 65, Issue 9, 2011, Pages 962-966

  Imai, Satoshi ^a   Sudo, Yuka ^b   Nakamura, Atsushi ^a   Ozeki, Ayumi ^a   Asato, Megumi ^a   Hojo, Minoru ^c   Devi, Lakshmi A ^d   Kuzumaki, Naoko ^a   Suzuki, Tsutomu ^a   Uezono, Yasuhito ^b,c   Narita, Minoru ^a  

^a HOSHI UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Fentanyl; Internalization recycling pathway; Opioids; Receptor trafficking

Indexed keywords

BETA ENDORPHIN; COMPLEMENTARY DNA; FENTANYL; MU OPIATE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA SEQUENCE; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; INTERNALIZATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANALGESICS, OPIOID; ANIMALS; BETA-ENDORPHIN; CELL LINE, TRANSFORMED; CRICETINAE; FENTANYL; MICROSCOPY, CONFOCAL; OXYCODONE; PROTEIN TRANSPORT; RECEPTORS, OPIOID, MU;

EID: 79959929492     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20930     Document Type: Article

References (13)

1. Claing A, Laporte SA, Caron MG, Lefkowitz RJ. 2002. Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Prog Neurobiol 66: 61-79.
2. Corbani M, Gonindard C, Meunier JC. 2004. Ligand-regulated internalization of the opioid receptor-like 1: A confocal study. Endocrinology 145: 2876-2885.
3. Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG. 2004. Desensitization of G protein-coupled receptors and neuronal functions. Annu Rev Neurosci 27: 107-144.
4. Haberstock-Debic H, Kim KA, Yu YJ, von Zastrow M. 2005. Morphine promotes rapid, arrestin-dependent endocytosis of μ-opioid receptors in striatal neurons. J Neurosci 25: 7847-7857.
5. Imai S, Narita M, Hashimoto S, Nakamura A, Miyoshi K, Nozaki H, Hareyama N, Takagi T, Suzuki M, Suzuki T. 2006. Differences in tolerance to anti-hyperalgesic effects between chronic treatment with morphine and fentanyl under a state of pain. Nihon Shinkei Seishin Yakurigaku Zasshi 26: 183-192.
6. Koch T, Widera A, Bartzsch K, Schulz S, Brandenburg LO, Wundrack N, Beyer A, Grecksch G, Hollt V. 2005. Receptor endocytosis counteracts the development of opioid tolerance. Mol Pharmacol 67: 280-287.
7. Minnis JG, Patierno S, Kohlmeier SE, Brecha NC, Tonini M, Sternini C. 2003. Ligand-induced mu opioid receptor endocytosis and recycling in enteric neurons. Neuroscience 119: 33-42.
8. Nagai T, Ibata K, Park ES, Kubota M, Mikoshiba K, Miyawaki A. 2002. A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat Biotechnol 20: 87-90.
9. Niikura K, Narita M, Nakamura A, Okutsu D, Ozeki A, Kurahashi K, Kobayashi Y, Suzuki M, Suzuki T. 2008. Direct evidence for the involvement of endogenous β-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state. Neurosci Lett 435: 257-262.
10. Niikura K, Narita M, Butelman ER, Kreek MJ, Suzuki T. 2010. Neuropathic and chronic pain stimuli downregulate central μ-opioid and dopaminergic transmission. Trends Pharmacol Sci 31: 299-305.
11. Schulz S, Mayer D, Pfeiffer M, Stumm R, Koch T, Hollt V. 2004. Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375. EMBO J 23: 3282-3289.
12. Smalheiser NR, Lugli G. 2009. microRNA regulation of synaptic plasticity. Neuromolecular Med 11: 133-140.
13. Zubieta JK, Smith YR, Bueller JA, Xu Y, Kilbourn MR, Jewett DM, Meyer CR, Koeppe RA, Stohler CS. 2001. Regional μ opioid receptor regulation of sensory and affective dimensions of pain. Science 293: 311-315.