Developing next generation antimicrobials by intercepting AI-2 mediated quorum sensing

Enzyme and Microbial Technology

Volumn 49, Issue 2, 2011, Pages 113-123

  Roy, Varnika ^a,b   Adams, Bryn L ^a   Bentley, William E ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

AI 2; Cell cell communication; Pathogenicity; Quorum quenching; Quorum sensing; Quorum sensing inhibitors

Indexed keywords

AI-2; CELL-CELL COMMUNICATIONS; PATHOGENICITY; QUORUM QUENCHING; QUORUM-SENSING; QUORUM-SENSING INHIBITORS;

ANTIBIOTICS; BACTERIOLOGY; ENZYME INHIBITION; ESCHERICHIA COLI; HEALTH RISKS; PLANTS (BOTANY); SALMONELLA; SIGNAL GENERATORS;

SIGNAL TRANSDUCTION;

2 AMINO 4 (2,3 DIHYDROXY 3 N HYDROXYCARBAMOYL PROPYLMERCAPTO)BUTYRIC ACID; 2 AMINO 4 (2,3 DIHYDROXY 3 N HYDROXYCARBAMOYLPROPYLMERCAPTO)BUTYRIC ACID; 4 BROMO 5 (BROMOMETHYLENE) 3 BUTYL 2(5H) FURANONE; 4 BROMO 5 5 (BROMOMETHYLENE) 2 (5H) FURANONE; ANTIBIOTIC AGENT; FIMBROLIDE; N ACYLHOMOSERINE LACTONE; S RIBOSYLHOMOCYSTEINASE; UNCLASSIFIED DRUG;

BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM CULTURE; BINDING SITE; BIOFILM; BIOLOGICAL ACTIVITY; BIOLUMINESCENCE; BIOMASS; BIOSYNTHESIS; CELL COMMUNICATION; COMPETITIVE INHIBITION; CRYSTAL STRUCTURE; CYSTIC FIBROSIS; DNA SYNTHESIS; DRUG EFFICACY; ESCHERICHIA COLI; GASTROENTERITIS; HAEMOPHILUS INFLUENZAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROARRAY ANALYSIS; MORAXELLA CATARRHALIS; NONHUMAN; OPERON; PHENOTYPE; PORPHYROMONAS GINGIVALIS; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; REVIEW; SALMONELLA ENTERICA; SIGNAL TRANSDUCTION; STREPTOCOCCUS GORDONII; STREPTOCOCCUS MUTANS; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ANALYSIS; UPREGULATION; URINARY TRACT INFECTION; VIBRIO CHOLERAE; VIBRIO HARVEYI; VIBRIO PARAHAEMOLYTICUS;

ANTI-INFECTIVE AGENTS; BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; DRUG DISCOVERY; HOMOSERINE; HUMANS; LACTONES; QUORUM SENSING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; VIBRIO CHOLERAE;

EID: 79959914661     PISSN: 01410229     EISSN: 18790909     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2011.06.001     Document Type: Review

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