Effects of ageing and endurance exercise training on alpha-actinin isoforms in rat plantaris muscle

Acta Physiologica

Volumn 202, Issue 4, 2011, Pages 683-690

  Ogura, Y ^a,b   Naito, H ^b   Kakigi, R ^b   Ichinoseki Sekine, N ^b   Kurosaka, M ^b,c   Yoshihara, T ^b   Akema, T ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c TOKAI UNIVERSITY   (Japan)

Author keywords

Aerobic capacity; Muscle fibre type; Myosin heavy chain; Running training

Indexed keywords

ALPHA ACTININ; ALPHA ACTININ 2; ALPHA ACTININ 3; CITRATE SYNTHASE; LACTATE DEHYDROGENASE; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN I; MYOSIN HEAVY CHAIN IIB; UNCLASSIFIED DRUG;

ADAPTATION; AEROBIC CAPACITY; AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDURANCE TRAINING; ENZYME ACTIVITY; EXERCISE INTENSITY; MALE; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; RAT; SITTING; TREADMILL EXERCISE;

ACTININ; ADAPTATION, PHYSIOLOGICAL; AGING; ANIMALS; MALE; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SLOW-TWITCH; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; PROTEIN ISOFORMS; RATS; RATS, INBRED F344;

EID: 79959908124     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2011.02284.x     Document Type: Article

References (25)

1. Bergmeyer, H.U., Bernt, E. & Hess, B. 1965. Lactic dehydrogenase. Methods in Enzymatic Analysis. Academic Press, New York.
2. Blanchard, A., Ohanian, V. & Critchley, D. 1989. The structure and function of alpha-actinin. J Muscle Res Cell Motil 10, 280-289.
3. Blough, E.R. & Linderman, J.K. 2000. Lack of skeletal muscle hypertrophy in very aged male Fischer 344 x Brown Norway rats. J Appl Physiol 88, 1265-1270.
4. Chan, Y., Tong, H.Q., Beggs, A.H. & Kunkel, L.M. 1998. Human skeletal muscle-specific alpha-actinin-2 and -3 isoforms form homodimers and heterodimers in vitro and in vivo. Biochem Biophys Res Commun 248, 134-139.
5. Chopard, A., Pons, F. & Marini, J.F. 2001. Cytoskeletal protein contents before and after hindlimb suspension in a fast and slow rat skeletal muscle. Am J Physiol Regul Integr Comp Physiol 280, R323-R330.
6. Chopard, A., Arrighi, N., Carnino, A. & Marini, J.F. 2005. Changes in dysferlin, proteins from dystrophin glycoprotein complex, costameres, and cytoskeleton in human soleus and vastus lateralis muscles after a long-term bedrest with or without exercise. FASEB J 19, 1722-1724.
7. Fitts, R.H., Troup, J.P., Witzmann, F.A. & Holloszy, J.O. 1984. The effect of ageing and exercise on skeletal muscle function. Mech Ageing Dev 27, 161-172.
8. Holloszy, J.O., Chen, M., Cartee, G.D. & Young, J.C. 1991. Skeletal muscle atrophy in old rats: differential changes in the three fibre types. Mech Ageing Dev 60, 199-213.
9. Klitgaard, H., Brunet, A., Maton, B., Lamaziere, C., Lesty, C. & Monod, H. 1989. Morphological and biochemical changes in old rat muscles: effect of increased use. J Appl Physiol 67, 1409-1417.
10. Luther, P.K. & Squire, J.M. 2002. Muscle Z-band ultrastructure: titin Z-repeats and Z-band periodicities do not match. J Mol Biol 319, 1157-1164.
11. MacArthur, D.G. & North, K.N. 2004. A gene for speed? The evolution and function of alpha-actinin-3. Bioessays 26, 786-795.
12. MacArthur, D.G. & North, K.N. 2007. ACTN3: a genetic influence on muscle function and athletic performance. Exerc Sport Sci Rev 35, 30-34.
13. MacArthur, D.G., Seto, J.T., Raftery, J.M., Quinlan, K.G., Huttley, G.A., Hook, J.W., Lemckert, F.A., Kee, A.J., Edwards, M.R., Berman, Y., Hardeman, E.C., Gunning, P.W., Easteal, S., Yang, N. & North, K.N. 2007. Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans. Nat Genet 39, 1261-1265.
14. MacArthur, D.G., Seto, J.T., Chan, S., Quinlan, K.G., Raftery, J.M., Turner, N., Nicholson, M.D., Kee, A.J., Hardeman, E.C., Gunning, P.W., Cooney, G.J., Head, S.I., Yang, N. & North, K.N. 2008. An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance. Hum Mol Genet 17, 1076-1086.
15. Mills, M., Yang, N., Weinberger, R., Vander Woude, D.L., Beggs, A.H., Easteal, S. & North, K. 2001. Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet 10, 1335-1346.
16. North, K.N. & Beggs, A.H. 1996. Deficiency of a skeletal muscle isoform of alpha-actinin (alpha-actinin-3) in merosin-positive congenital muscular dystrophy. Neuromuscul Disord 6, 229-235.
17. Ogura, Y., Naito, H., Kakigi, R., Ichinoseki-Sekine, N., Kurosaka, M. & Katamoto, S. 2008. Alpha-actinin-3 levels increase concomitantly with fast fibres in rat soleus muscle. Biochem Biophys Res Commun 372, 584-588.
18. Ogura, Y., Naito, H., Kakigi, R., Akema, T., Sugiura, T., Katamoto, S. & Aoki, J. 2009. Different adaptations of alpha-actinin isoforms to exercise training in rat skeletal muscles. Acta Physiol (Oxf) 196, 341-349.
19. Radak, Z., Naito, H., Kaneko, T., Tahara, S., Nakamoto, H., Takahashi, R., Cardozo-Pelaez, F. & Goto, S. 2002. Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflugers Arch 445, 273-278.
20. Roth, S.M., Walsh, S., Liu, D., Metter, E.J., Ferrucci, L. & Hurley, B.F. 2008. The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. Eur J Hum Genet 16, 391-394.
21. Srere, P. 1969. Citrate synthase. Meth Enzymol 13, 3-11.
22. Sugiura, T. & Murakami, N. 1990. Separation of myosin heavy chain isoforms in rat skeletal muscles by gradient sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biomed Res 11, 87-91.
23. Takekura, H. & Yoshioka, T. 1987. Determination of metabolic profiles on single muscle fibres of different types. J Muscle Res Cell Motil 8, 342-348.
24. Taylor, K.N., Taylor D.W. & Schachat, F. 2000. Isoform of alpha-actinin from cardiac, smooth, and skeletal muscle form polar arrays of actinin filaments. J Cell Biol 149, 635-645.
25. Vincent, B., De Bock, K., Ramaekers, M., Van den Eede, E., Van Leemputte, M., Hespel, P. & Thomis, M.A. 2007. ACTN3 (R577X) genotype is associated with fibre type distribution. Physiol Genomics 32, 58-63.