Growth Hormone for Intestinal Adaptation in Patients With Short Bowel Syndrome: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Current Therapeutic Research - Clinical and Experimental

Volumn 72, Issue 3, 2011, Pages 109-119

  Guo, Ming Xiao ^a   Li, You Sheng ^a   Fan, Lei ^a   Li, Jie Shou ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Growth hormone; Meta analysis; Randomized controlled trial; Short bowel syndrome; Systematic review

Indexed keywords

GLUTAMINE; GROWTH HORMONE; NITROGEN; PLACEBO; SOMATOMEDIN C;

ARTHRALGIA; ARTICLE; BODY WEIGHT; CRYPT CELL; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ENERGY ABSORPTION; ENTEROPATHY; FOLLOW UP; GASTROINTESTINAL SYMPTOM; GYNECOMASTIA; HUMAN; HYPERPLASIA; HYPERTROPHY; INTESTINE ABSORPTION; INTESTINE ADAPTATION; INTESTINE HYPERPLASIA; INTESTINE HYPERTROPHY; LEAN BODY WEIGHT; LIPID ABSORPTION; LOW DRUG DOSE; META ANALYSIS; MORTALITY; MYALGIA; NIGHTMARE; OUTCOME ASSESSMENT; PERIPHERAL EDEMA; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SHORT BOWEL SYNDROME; SYSTEMATIC REVIEW; TREATMENT DURATION;

EID: 79959900599     PISSN: 0011393X     EISSN: 18790313     Source Type: Journal    
DOI: 10.1016/j.curtheres.2011.04.002     Document Type: Article

References (23)

1. O'Keefe S.J., Buchman A.L., Fishbein T.M., et al. Short bowel syndrome and intestinal failure: consensus definitions and overview. Clin Gastroenterol Hepatol 2006, 4:6-10.
2. Sondheimer J.M., Asturias E., Cadnapaphornchai M. Infection and cholestasis in neonates with intestinal resection and long-term parenteral nutrition. J Pediatr Gastroenterol Nutr 1998, 27:131-137.
3. Burstyne M., Jensen G.L. Abnormal liver functions as a result of total parenteral nutrition in a patient with short-bowel syndrome. Nutrition 2000, 16:1090-1092.
4. Terra R.M., Plopper C., Waitzberg D.L., et al. Remaining small bowel length: association with catheter sepsis in patients receiving home total parenteral nutrition: evidence of bacterial translocation. World J Surg 2000, 24:1537-1541.
5. Candusso M., Faraguna D., Sperli D., Dodaro N. Outcome and quality of life in paediatric home parenteral nutrition. Curr Opin Clin Nutr Metab Care 2002, 5:309-314.
6. Byrne T.A., Morrissey T.B., Nattakom T.V., et al. Growth hormone, glutamine, and a modified diet enhance nutrient absorption in patients with severe short-bowel syndrome. JPEN J Parenter Enteral Nutrition 1995, 19:296-302.
7. Scolapio J.S., Camilleri M., Fleming C.R., et al. Effect of growth hormone, glutamine, and diet on adaptation in short-bowel syndrome: a randomized, controlled study. Gastroenterology 1997, 113:1074-1081.
8. Seguy D., Vahedi K., Kapel N., et al. Low-dose growth hormone in adult home parenteral nutrition-dependent short bowel syndrome patients: a positive study. Gastroenterology 2003, 124:293-302.
9. Byrne T.A., Wilmore D.W., Iyer K., et al. Growth hormone, glutamine, and an optimal diet reduces parenteral nutrition in patients with short bowel syndrome: a prospective, randomized, placebo-controlled, double-blind clinical trial. Ann Surg 2005, 242:655-661.
10. Ellegard L., Bosaeus I., Nordgren S., Bengtsson B.A. Low-dose recombinant human growth hormone increases body weight and lean body mass in patients with short bowel syndrome. Ann Surg 1997, 225:88-96.
11. Scolapio J.S. Effect of growth hormone, glutamine, and diet on body composition in short bowel syndrome: a randomized, controlled study. JPEN J Parenter Enteral Nutr 1999, 23:309-313.
12. Szkudlarek J., Jeppesen P.B., Mortensen P.B. Effect of high dose growth hormone with glutamine and no change in diet on intestinal absorption in short bowel patients: a randomised, double blind, crossover, placebo controlled study. Gut 2000, 47:199-205.
13. Jeppesen P.B., Szkudlarek J., Høy C.E., Mortensen P.B. Effect of high-dose growth hormone and glutamine on body composition, urine creatinine excretion, fatty acid absorption, and essential fatty acids status in short bowel patients: a randomized, double-blind, crossover, placebo-controlled study. Scand J Gastroenterol 2001, 36:48-54.
14. Ulshen M.H., Dowling R.H., Fuller C.R., et al. Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone. Gastroenterology 1993, 104:973-980.
15. Park J.H., Vanderhoof J.A. Growth hormone did not enhance mucosal hyperplasia after small-bowel resection. Scand J Gastroenterol 1996, 31:349-354.
16. Lemmey A.B., Martin A.A., Read L.C., et al. IGF-1 and the truncated analogue des-(1-3) IGF-1 enhance growth in rats after gut resection. Am J Physiol 1991, 260:E213-E219.
17. Inoue Y., Copeland E.M., Souba W.W. Growth hormone enhances amino acid uptake by the human small intestine. Ann Surg 1994, 219:715-724.
18. Challacombe D.N., Wheeler E.E. The trophic action of human growth hormone on human duodenal mucosa cultured in vitro. J Pediatr Gastroenterol Nutr 1995, 21:50-53.
19. Jiang X., Zhu W., Li N., et al. Effects of continuous enteral L-arginine in a rat model of the short bowel syndrome. Asia Pac J Clin Nutr 2007, 16:554-560.
20. van der Hulst R.R., van Kreel B.K., von Meyenfeldt M.F., et al. Glutamine and the preservation of gut integrity. Lancet 1993, 341:1363-1365.
21. Rhoads J.M., Argenzio R.A., Chen W., et al. L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases. Am J Physiol 1997, 272:G943-G953.
22. Lobie P.E., Breipohl W., Waters M.J. Growth hormone receptor expression in the rat gastrointestinal tract. Endocrinology 1990, 126:299-306.
23. Zhou Y., Wu X.T., Yang G., et al. Clinical evidence of growth hormone, glutamine and a modified diet for short bowel syndrome: meta-analysis of clinical trials. Asia Pac J Clin Nutr 2005, 14:98-102.