Phase I and pharmacokinetic study of IV vinflunine in combination with gemcitabine for treatment of advanced non-small cell lung cancer in chemonaive patients

Journal of Thoracic Oncology

Volumn 6, Issue 7, 2011, Pages 1247-1253

  Tournoux Facon, Caroline ^a   Senellart, Hélène ^b   Lemarie, Etienne ^c   Tourani, Jean Marc ^a   Favrel, Stéphanie ^d   Pouget, Jean Christophe ^d   Pinel, Marie Claire ^d   Bennouna, Jaafar ^a  

^a POITIERS UNIVERSITY HOSPITAL   (France)

^b CENTRE RENÉ GAUDUCHEAU   (France)

^c UNIVERSITY HOSPITAL OF TOURS   (France)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Gemcitabine; Lung cancer; Pharmacokinetics; Phase I; Vinflunine

Indexed keywords

GEMCITABINE; VINFLUNINE;

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; AGED; ALOPECIA; ANEMIA; ANOREXIA; AREA UNDER THE CURVE; ARTICLE; ASTHENIA; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER PATIENT; CANCER SURVIVAL; CLINICAL ARTICLE; CONSTIPATION; CONTROLLED STUDY; DIARRHEA; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG WITHDRAWAL; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; HUMAN; HYPERTENSION; JAW PAIN; LARGE CELL CARCINOMA; LEUKOPENIA; LUNG ADENOCARCINOMA; LUNG INFECTION; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MALE; MAXIMUM TOLERATED DOSE; MOTOR NEUROPATHY; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; MYALGIA; NAUSEA; NEUTROPENIA; OPEN STUDY; OVERALL SURVIVAL; PERIPHERAL NEUROPATHY; PHASE 1 CLINICAL TRIAL; PHLEBITIS; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RECOMMENDED DRUG DOSE; SENSORY NEUROPATHY; STOMATITIS; SYNCOPE; THROMBOCYTOPENIA; TREATMENT RESPONSE; VOMITING;

EID: 79959862952     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e31821b0f3b     Document Type: Article

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